Zachary Most, M.D.

Zachary Most, M.D.

  • Pediatrics - Infectious Disease
  • Pediatric infectious disease
  • Respiratory viral infections


Zachary M. Most, M.D., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center. He specializes in pediatric infectious disease.

Dr. Most earned his medical degree at the University of Miami and completed a residency in pediatrics at UT Southwestern and Children's Health Dallas. He received advanced training in pediatric infectious disease through a fellowship at UT Southwestern.

Certified in pediatrics and pediatric infectious disease by the American Board of Pediatrics, Dr. Most joined the UT Southwestern faculty in 2021.

Dr. Most is the Associate Medical Director of Infection Prevention and Control at Children’s Health Dallas and serves on the COVID-19 Modeling Group and the Optum Database Research Group at UT Southwestern. He is a member of the American Academy of Pediatrics, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society for Healthcare Epidemiology of America.

Dr. Most has authored research articles, case reports, and reviews and delivered numerous invited lectures. His clinical interests include transmission dynamics of respiratory viral infections in health care settings and respiratory virus surveillance in the community and health care settings.

Education & Training
  • Other Post Graduate Training - London School of Hygiene and Tropical Medicine (2019-2021)
  • Fellowship - UT Southwestern/Children's Medical Center (2018-2021), Pediatric Infectious Diseases
  • Residency - UT Southwestern/Children's Medical Center (2015-2018), Pediatrics
  • Medical School - University of Miami School of Medicine (2011-2015)
Professional Associations & Affiliations
  • American Academy of Pediatrics
  • Infectious Diseases Society of America
  • Pediatric Infectious Diseases Society
  • Society for Healthcare Epidemiology of America
Honors & Awards
  • IDWeek 2020 Trainee Award, Infectious Diseases Society of America
  • IDWeek 2018 Trainee Award, Infectious Diseases Society of America
  • Excellence in Scholarship for Research, UT Southwestern
  • Alpha Omega Alpha Honor Medical Society
  • Research Distinction, University of Miami Miller School of Medicine
Books & Publications
  • Health care-associated respiratory viral infections: epidemiology and transmission dynamics
  • The impact of nonpharmaceutical interventions on community respiratory virus transmission
  • COVID-19 in children: risk factors for infection and for severe disease

Clinical Focus

  • Pediatric infectious disease
  • Respiratory viral infections
  • Hospital epidemiology

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