- American Academy of Pediatrics
- Infectious Diseases Society of America
- Pediatric Infectious Diseases Society
- Society for Healthcare Epidemiology of America
Zachary Most, M.D.
- Pediatrics - Infectious Disease
- Pediatric infectious disease
- Respiratory viral infections
Biography
Zachary M. Most, M.D., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center. He specializes in pediatric infectious disease.
Dr. Most earned his medical degree at the University of Miami and completed a residency in pediatrics at UT Southwestern and Children's Health Dallas. He received advanced training in pediatric infectious disease through a fellowship at UT Southwestern.
Certified in pediatrics and pediatric infectious disease by the American Board of Pediatrics, Dr. Most joined the UT Southwestern faculty in 2021.
Dr. Most is the Associate Medical Director of Infection Prevention and Control at Children’s Health Dallas and serves on the COVID-19 Modeling Group and the Optum Database Research Group at UT Southwestern. He is a member of the American Academy of Pediatrics, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society for Healthcare Epidemiology of America.
Dr. Most has authored research articles, case reports, and reviews and delivered numerous invited lectures. His clinical interests include transmission dynamics of respiratory viral infections in health care settings and respiratory virus surveillance in the community and health care settings.
Education & Training
- Other Post Graduate Training - London School of Hygiene and Tropical Medicine (2019-2021)
- Fellowship - UT Southwestern/Children's Medical Center (2018-2021), Pediatric Infectious Diseases
- Residency - UT Southwestern/Children's Medical Center (2015-2018), Pediatrics
- Medical School - University of Miami School of Medicine (2011-2015)
Professional Associations & Affiliations
Honors & Awards
- D Magazine Best Doctor 2024-2025
- IDWeek 2020 Trainee Award, Infectious Diseases Society of America
- IDWeek 2018 Trainee Award, Infectious Diseases Society of America
- Excellence in Scholarship for Research, UT Southwestern
- Alpha Omega Alpha Honor Medical Society
- Research Distinction, University of Miami Miller School of Medicine
Books & Publications
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Publications
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Factors Affecting Maternal Respiratory Syncytial Virus Vaccination and the Impact on Infant Hospitalization During the 2023-2024 Season in Dallas, Texas
Bailey NA, Most ZM Public Health Reports 2026 -
Potential for misclassification of community-acquired respiratory virus infections as healthcare-associated respiratory virus infections at a pediatric healthcare system
Most ZM, Perl TM, Sebert M Infection Control and Hospital Epidemiology 2026 -
Multiyear environmental surveillance in a pediatric teaching hospital: association between airborne mold spores and invasive mold infections
Phillips B, Most ZM, Connors B, Jackson P, Sebert ME Infection Control and Hospital Epidemiology 2025 Nov 46 1119-1126 -
Does serial procalcitonin monitoring predict clinical outcomes in children with sepsis? A diagnostic stewardship study
Rubbab B, Davila S, Moreland J, Firmani S, Most Z Antimicrobial Stewardship and Healthcare Epidemiology 2025 Jun 5 -
Preoperative Antibiotic Compliance and Colorectal Surgical Site Infection in Children
Templeton LR, Most ZM, Bradd MV, Kluger S, Reisch JS, Hansen EN, Pandya SR Journal of Surgical Research 2025 May 309 1-7 -
Birds of a feather? Mis- and dis-information on the social media platform X related to avian influenza
Cooper LN, Diaz MI, Hanna JJ, Most ZM, Lehmann CU, Medford RJ Antimicrobial Stewardship and Healthcare Epidemiology 2025 Jan 5 -
Socioeconomic Disparities and the Prevalence of Antimicrobial Resistance
Cooper LN, Beauchamp AM, Ingle TA, Diaz MI, Wakene AD, Katterpalli C, Keller T, Walker C, Blumberg S, Kanjilal S, Chen JH, Radunsky AP, Most ZM, Hanna JJ, Perl TM, Lehmann CU, Medford RJ Clinical Infectious Diseases 2024 Dec 79 1346-1353 -
Respiratory virus infections in symptomatic and asymptomatic children upon hospital admission: new insights
Most ZM, Perl TM, Sebert M Antimicrobial Stewardship and Healthcare Epidemiology 2024 Oct 4 -
Mortality in hospitalized SARS-CoV-2 patients with contemporaneous bacterial and fungal infections
Hanna JJ, Most ZM, Cooper LN, Wakene AD, Radunsky AP, Lehmann CU, Perl TM, Medford RJ Antimicrobial Stewardship and Healthcare Epidemiology 2024 Sep 4 -
Risk factors for healthcare-associated candidemia in adults hospitalized with SARS-CoV-2 infection
Most ZM, Hanna JJ, Radunsky AP, Cooper LN, Lehmann CU, Perl TM, Medford RJ Antimicrobial Stewardship and Healthcare Epidemiology 2024 May 4 -
Discontinuation of Contact Precautions for Methicillin-resistant Staphylococcus aureus in a Pediatric Healthcare System
Most ZM, Phillips B, Sebert ME Journal of the Pediatric Infectious Diseases Society 2024 Feb 13 123-128 -
Healthcare-associated respiratory viral infections after discontinuing universal masking
Most ZM, Phillips B, Sebert ME Infection Control and Hospital Epidemiology 2024 Feb 45 247-249 -
Gastrointestinal Manifestations Are Associated with Severe COVID-19 in Children
Akkoyun EB, Ashraf B, Hanners N, Kahn J, Most Z Healthcare (Switzerland) 2024 Jan 12 -
Impact of anakinra use on clinical outcomes in children with moderate or severe multisystem inflammatory syndrome in children: a propensity score matched retrospective cohort study
Akkoyun EB, Most Z, Katragadda H, Yu A, Nassi L, Oakman N, Ginsburg S, Maamari M Pediatric Rheumatology 2023 Dec 21 -
Risk Factors for SARS-CoV-2 Infection and Severe Outcomes Among People With Human Immunodeficiency Virus: Cohort Study
Hanna JJ, Geresu LB, Diaz MI, Ho M, Casazza JA, Pickering MA, Lanier HD, Radunsky AP, Cooper LN, Saleh SN, Bedimo RJ, Most ZM, Perl TM, Lehmann CU, Turer RW, Chow JY, Medford RJ Open Forum Infectious Diseases 2023 Aug 10 -
Incidence and Risk Factors for Severe Outcomes in Pediatric Patients With COVID-19
Ho M, Most ZM, Perl TM, Diaz MI, Casazza JA, Saleh S, Pickering M, Radunsky AP, Hanna JJ, Thakur B, Lehmann CU, Medford RJ, Turer RW Hospital Pediatrics 2023 May 13 450-458 -
Analyzing an Emerging Pandemic on Twitter: Monkeypox
Cooper LN, Radunsky AP, Hanna JJ, Most ZM, Perl TM, Lehmann CU, Medford R Open Forum Infectious Diseases 2023 Apr 10 -
Preschool-Aged Household Contacts as a Risk Factor for Viral Respiratory Infections in Healthcare Personnel
Most ZM, Nyquist AC, Radonovich LJ, Rodriguez-Barradas MC, Price CS, Simberkoff MS, Bessesen MT, Cummings DA, Rattigan SM, Warren-Gash C, Gaydos CA, Gibert CL, Gorse GJ, Perl TM Open Forum Infectious Diseases 2023 Feb 10 -
Contrasting definitions and incidence of healthcare-associated respiratory viral infections in a pediatric hospital
Most ZM, Jackson P, Sebert M, Perl TM Infection Control and Hospital Epidemiology 2023 Jan 44 55-61 -
A Silver Lining? Fewer Non–Severe Acute Respiratory Syndrome Coronavirus 2 Respiratory Viruses During the Coronavirus Disease 2019 Pandemic
Most ZM, Holcomb M, Jamieson AR, Perl TM Journal of Infectious Diseases 2021 Nov 224 1751-1755 -
Missed Opportunity Encounters for Early Diagnosis of HIV Infection in Adolescents
Most ZM, Warraich GJ, James L, Costello K, Dietz S, Lamb GS, Evans AS Pediatric Infectious Disease Journal 2021 Mar 40 E106-E110 -
Striking Similarities of Multisystem Inflammatory Syndrome in Children and a Myocarditis-Like Syndrome in Adults Overlapping Manifestations of COVID-19
Most ZM, Hendren N, Drazner MH, Perl TM Circulation 2021 Jan 143 4-6 -
Disseminated nannizziopsis infection in an adolescent with a STAT1 mutation
Most ZM, Lieu T, Filkins L, Nicolaides R, Rakheja D, Gelfand A, Kahn J Open Forum Infectious Diseases 2020 Sep 7 -
Beyond personal protective equipment: Adjunctive methods for control of healthcare-associated respiratory viral infections
Most ZM Current Opinion in Infectious Diseases 2020 Aug 33 312-318 -
Transarterial embolization of Intractable nasal and oropharyngeal hemorrhage using liquid embolic agents
Hayes SB, Johnson JN, Most Z, Elhammady MS, Yavagal D, Aziz-Sultan MA Journal of NeuroInterventional Surgery 2015 Jul 7 537-541
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Factors Affecting Maternal Respiratory Syncytial Virus Vaccination and the Impact on Infant Hospitalization During the 2023-2024 Season in Dallas, Texas
Research
- Health care-associated respiratory viral infections: epidemiology and transmission dynamics
- The impact of nonpharmaceutical interventions on community respiratory virus transmission
- COVID-19 in children: risk factors for infection and for severe disease
Clinical Focus
- Pediatric infectious disease
- Respiratory viral infections
- Hospital epidemiology
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas