Adrienne Shannon, M.D.

Surgery - Surgical Oncology
Melanoma
Non-Melanoma Skin Cancers

Biography

Adrienne Shannon, M.D., is an Assistant Professor in the Department of Surgery at UT Southwestern Medical Center. She specializes in cutaneous surgical oncology and soft tissue tumors.

Dr. Shannon earned her medical degree at Georgetown University School of Medicine. She completed a residency in general surgery within the University of Pennsylvania Health System and received advanced training through a complex general surgical oncology fellowship at the Moffitt Cancer Center in Tampa, Florida.

Certified by the American Board of Surgery in general surgery, she joined the UT Southwestern faculty in 2025.

Dr. Shannon has delivered national and international presentations, contributed to the book Practical Manual for Dermatologic and Surgical Melanoma Management, and published more than 50 academic articles related to her areas of expertise.

She is a member of the American College of Surgeons and its Surgical Outcomes Club, and the Society of Surgical Oncology.

Personal Note

When she’s not at work, Dr. Shannon enjoys spending time with her family, including her three children. She also enjoys photography and travel.

Education & Training

Medical School - Georgetown University School of Medicine (2012-2016)
Residency - University of Pennsylvania Health System (2016-2023), General Surgery
Fellowship - Moffitt Cancer Center & Research Institute (2023-2025), Surgical Oncology

Professional Associations & Affiliations

American College of Surgeons
Society of Surgical Oncology
American College of Surgeons Surgical Outcomes Club
Society for Melanoma Research
International Neoadjuvant Melanoma Consortium

Honors & Awards

Dale Han MD Memorial Scholarship Award 2022, Society of Surgical Oncology and the Sentinel Node Oncology Foundation
Travel Award 2020, Advanced Cancer Therapies and the Appendix Cancer Pseudomyxoma Peritonei Research Foundation

Books & Publications

Books
- Regional nodal staging: clinically node negative in Practical Manual for Dermatologic and Surgical Melanoma Management
  Song Y, Bruce AN, Tieniber AD, Xu X, Karakousis GC. (2020), Cham, Switzerland, Springer
Publications
- Analysis of the Incidence of Lymph Node Metastases in High-Risk Early Stage (T1) Esophageal Adenocarcinomas: A Single-Institution Experience.
  Shannon AB, Mohammed MA, Lauwers GY, Pena LR, Mok SR, Sinnamon AJ, Araujo CR, Pimiento JM, Journal of surgical oncology 2025 Jul
- Regional Therapies for Melanoma and Merkel Cell Carcinoma.
  Shannon AB, Zager JS, The Surgical clinics of North America 2025 Jun 105 3 591-613
- In Brief.
  Dugan MM, Shannon AB, DePalo DK, Tsai KY, Farma JM, Gonzalez RJ, Zager JS, Current problems in surgery 2025 Feb 63 101564
- Current management of nonmelanoma skin cancers.
  Dugan MM, Shannon AB, DePalo DK, Tsai KY, Farma JM, Gonzalez RJ, Zager JS, Current problems in surgery 2025 Jan 62 101565
- ASO Author Reflections: Neoadjuvant Immunotherapy in DNA Mismatch Repair Protein-Deficient Gastroesophageal Cancers.
  Shannon AB, Sinnamon AJ, Annals of surgical oncology 2024 Dec 31 13 8680-8681
- Clinical and Pathologic Response to Neoadjuvant Immunotherapy in DNA Mismatch Repair Protein-Deficient Gastroesophageal Cancers.
  Shannon AB, Mehta R, Mok SR, Lauwers GY, Baldonado JJAR, Fontaine J, Pimiento JM, Sinnamon AJ, Annals of surgical oncology 2024 Dec 31 13 8616-8626
- Clinical Characteristics and Special Considerations in the Management of Rare Melanoma Subtypes.
  Shannon AB, Zager JS, Perez MC, Cancers 2024 Jun 16 13
- Intralesional and Infusional Updates for Metastatic Melanoma.
  Dugan MM, Shannon AB, DePalo DK, Perez MC, Zager JS, Cancers 2024 May 16 11
- The impact of the COVID-19 pandemic on new diagnoses of melanoma: A response to additional multi-institution and international reports.
  Shannon AB, Karakousis GC, Journal of the American Academy of Dermatology 2023 Nov 89 5 e221-e222
- Sentinel lymph node biopsy in patients with T1a cutaneous malignant melanoma: A multicenter cohort study.
  Shannon AB, Sharon CE, Straker RJ, Carr MJ, Sinnamon AJ, Bogatch K, Thaler A, Kelly N, Vetto JT, Fowler G, DePalo D, Sondak VK, Miura JT, Faries MB, Bartlett EK, Zager JS, Karakousis GC, Journal of the American Academy of Dermatology 2023 Jan 88 1 52-59
- Patterns of recurrence and prognosis in pathologic stage I and II Merkel cell carcinoma: A multicenter, retrospective cohort analysis.
  Tieniber AD, Shannon AB, Carr MJ, Sun J, Landa K, Baecher KM, Lynch K, Bartels HG, Panchaud R, Lowe MC, Slingluff CL, Jameson MJ, Tsai KY, Faries MB, Beasley GM, Sondak VK, Karakousis GC, Zager JS, Miura JT, Journal of the American Academy of Dermatology 2023 Jan 88 1 251-253
- Impact of the affordable care act's medicaid expansion on presentation stage and perioperative outcomes of colorectal cancer.
  Sharon CE, Song Y, Straker RJ, Kelly N, Shannon AB, Kelz RR, Mahmoud NN, Saur NM, Miura JT, Karakousis GC, Journal of surgical oncology 2022 Dec 126 8 1471-1480
- An Internally Validated Prognostic Risk-Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma.
  Shannon AB, Straker RJ, Carr MJ, Sun J, Landa K, Baecher K, Lynch K, Bartels HG, Panchaud R, Keele LJ, Lowe MC, Slingluff CL, Jameson MJ, Tsai KY, Faries MB, Beasley GM, Sondak VK, Karakousis GC, Zager JS, Miura JT, Annals of surgical oncology 2022 Oct 29 11 7033-7044
- Local recurrence in patients undergoing wide excision and sentinel lymph node biopsy for cutaneous malignant melanoma: A single-center, retrospective cohort analysis.
  Straker RJ, Kelly N, Sharon CE, Shannon AB, Xu X, Elder DE, Chu EY, Miura JT, Karakousis GC, Journal of the American Academy of Dermatology 2022 Jul 87 1 247-250
- Acral lentiginous melanoma in the era of immune checkpoint blockade and targeted therapy: A National Cancer Database analysis.
  Straker RJ, Thaler AS, Shannon AB, Miura JT, Chu EY, Karakousis GC, Ming ME, Journal of the American Academy of Dermatology 2022 Jul 87 1 169-172
- Predictive risk-score model for selection of patients with high-risk stage II colon cancer for adjuvant systemic therapy.
  Straker RJ, Heo DHJ, Shannon AB, Fraker DL, Shanmugan S, Schneider CJ, Mahmoud NN, Miura JT, Karakousis GC, Surgery 2022 Jun 171 6 1473-1479
- Implications of Lymph Node Evaluation in Crohn's Patients with Small-Bowel Adenocarcinoma.
  Straker RJ, Shannon AB, Roses RR, Fraker DL, Mahmoud NN, Miura JT, Karakousis GC, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2022 Jun 26 6 1311-1313
- Are Volume Pledge Standards Worth the Travel Burden for Major Abdominal Cancer Operations?
  Song Y, Shannon AB, Concors SJ, Roses RE, Fraker DL, DeMatteo RP, Kelz RR, Karakousis GC, Annals of surgery 2022 Jun 275 6 e743-e751
- Validated Risk-Score Model Predicting Lymph Node Metastases in Patients with Non-Functional Gastroenteropancreatic Neuroendocrine Tumors.
  Shannon AB, Straker RJ, Fraker DL, Miura JT, Karakousis GC, Journal of the American College of Surgeons 2022 May 234 5 900-909
- Pathologic Factors Associated with Low Risk of Lymph Node Metastasis in Nonmucinous Adenocarcinoma of the Appendix.
  Straker RJ, Grinberg SZ, Sharon CE, Shannon AB, Fraker DL, Shanmugan S, Miura JT, Karakousis GC, Annals of surgical oncology 2022 Apr 29 4 2334-2343
- The impact of hospital volume on racial disparities in resected rectal cancer.
  Shannon AB, Straker RJ, Keele L, Kelz RR, Fraker DL, Roses RE, Miura JT, Karakousis GC, Journal of surgical oncology 2022 Mar 125 3 465-474
- Neoadjuvant radiation for cutaneous and soft tissue angiosarcoma.
  Sharon CE, Straker RJ, Shannon AB, Shabason JE, Zhang PJL, Fraker DL, Miura JT, Karakousis GC, Journal of surgical oncology 2022 Mar 125 3 509-515
- ASO Author Reflections: Number of Examined Lymph Nodes in Gastric Cancer Resection Following Neoadjuvant Chemotherapy.
  Shannon AB, Karakousis GC, Annals of surgical oncology 2022 Feb 29 2 1254-1255
- Current management of melanoma patients with nodal metastases.
  Han D, van Akkooi ACJ, Straker RJ, Shannon AB, Karakousis GC, Wang L, Kim KB, Reintgen D, Clinical & experimental metastasis 2022 Feb 39 1 181-199
- Surgical resection of gastric gastrointestinal stromal tumors (GIST) in octogenarians.
  Shannon AB, Song Y, Fraker DL, Roses RE, DeMatteo RP, Miura JT, Karakousis GC, American journal of surgery 2022 Feb 223 2 325-330
- Lymph Node Evaluation after Neoadjuvant Chemotherapy for Patients with Gastric Cancer.
  Shannon AB, Straker RJ, Keele L, Fraker DL, Roses RE, Miura JT, Karakousis GC, Annals of surgical oncology 2022 Feb 29 2 1242-1253
- Optimizing Detection of Lymphatic Invasion in Primary Cutaneous Melanoma With the Use of D2-40 and a Paired Melanocytic Marker.
  Straker RJ, Taylor LA, Neuwirth MG, Sinnamon AJ, Shannon AB, Abbott J, Miura JT, Chu EY, Xu X, Karakousis GC, The American Journal of dermatopathology 2022 Jan 44 1 21-27
- Predictors of False Negative Sentinel Lymph Node Biopsy in Clinically Localized Merkel Cell Carcinoma.
  Straker RJ, Carr MJ, Sinnamon AJ, Shannon AB, Sun J, Landa K, Baecher KM, Wood C, Lynch K, Bartels HG, Panchaud R, Lowe MC, Slingluff CL, Jameson MJ, Tsai K, Faries MB, Beasley GM, Sondak V, Karakousis GC, Zager JS, Miura JT, Annals of surgical oncology 2021 Nov 28 12 6995-7003
- Preoperative Biopsy in Patients with Retroperitoneal Sarcoma: Usage and Outcomes in a National Cohort.
  Straker RJ, Song Y, Shannon AB, Marcinak CT, Miura JT, Fraker DL, Karakousis GC, Annals of surgical oncology 2021 Oct 28 11 6868-6879
- Patient characteristics, outcomes, and trends in extremity sarcoma management by surgeon specialty.
  Shannon AB, Straker RJ, Song Y, Kelz RR, Miura JT, Karakousis GC, Surgery 2021 Oct 170 4 1168-1174
- Response to a letter to the editor regarding "limitations of using the National Cancer Database to examine the effect of policy change on stage at presentation at the population-level".
  Straker RJ, Song Y, Shannon AB, Chu EY, Miura JT, Ming ME, Karakousis GC, Journal of the American Academy of Dermatology 2021 Sep 85 3 e197-e198
- Age and Mitogenicity are Important Predictors of Sentinel Lymph Node Metastasis in T1a Melanoma.
  Shannon AB, Wood C, Straker RJ, Miura JT, Ming ME, Elenitsas R, Karakousis GC, Annals of surgical oncology 2021 Sep 28 9 4777-4779
- What is the patient experience of surgical care during the coronavirus disease 2019 (COVID-19) pandemic? A mixed-methods study at a single institution.
  Shannon AB, Roberson JL, Clapp JT, Vaughan C, Kleid M, Song Y, Miura JT, Dempsey DT, DeMatteo RP, Fleisher LA, Karakousis GC, Surgery 2021 Aug 170 2 550-557
- Ninety-day mortality after total gastrectomy for gastric cancer.
  Shannon AB, Straker RJ, Fraker DL, Roses RE, Miura JT, Karakousis GC, Surgery 2021 Aug 170 2 603-609
- Adjuvant Radiation Therapy for Clinical Stage III Melanoma in the Modern Therapeutic Era.
  Straker RJ, Song Y, Sun J, Shannon AB, Cohen LS, Muradova E, Daou H, Krause K, Li S, Frederick DT, Rhodin KE, Brizel DM, Boland GM, Beasley GM, Wuthrick EJ, Sondak VK, Zager JS, Lin A, Lukens JN, Karakousis GC, Annals of surgical oncology 2021 Jul 28 7 3512-3521
- Association of the Affordable Care Act's Medicaid expansion with the diagnosis and treatment of clinically localized melanoma: A National Cancer Database study.
  Straker RJ, Song Y, Shannon AB, Chu EY, Miura JT, Ming ME, Karakousis GC, Journal of the American Academy of Dermatology 2021 Jun 84 6 1628-1635
- Preoperative Transfusion for Anemia in Patients Undergoing Abdominal Surgery for Malignancy.
  Shannon AB, Song Y, Davis Rivera LB, Roses RE, Fraker DL, Kelz RR, Miura JT, Karakousis GC, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2021 Jun 25 6 1534-1544
- Modified Metabolic Syndrome Predicts Worse Outcomes in Obese Patients Undergoing Inguinal Hernia Repair.
  Shannon AB, Kelz RR, Williams NN, Karakousis GC, Dumon KR, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2021 Jun 25 6 1565-1568
- Impact of COVID-19 Restrictions on Demographics and Outcomes of Patients Undergoing Medically Necessary Non-Emergent Surgeries During the Pandemic.
  Shannon AB, Roberson JL, Keele L, Bharani T, Song Y, Miura JT, Kelz RR, Dempsey DT, Fleisher LA, DeMatteo RP, Karakousis GC, World journal of surgery 2021 Apr 45 4 946-954
- The impact of the COVID-19 pandemic on the presentation status of newly diagnosed melanoma: A single institution experience.
  Shannon AB, Sharon CE, Straker RJ, Miura JT, Ming ME, Chu EY, Karakousis GC, Journal of the American Academy of Dermatology 2021 Apr 84 4 1096-1098
- Do microscopic surgical margins matter for primary gastric gastrointestinal stromal tumor?
  Shannon AB, Song Y, Fraker DL, Roses RE, DeMatteo RP, Miura JT, Karakousis GC, Surgery 2021 Feb 169 2 419-425
- National trends in the presentation of surgically resected appendiceal adenocarcinoma over a decade.
  Shannon AB, Song Y, Roses RE, Fraker DL, Miura JT, Karakousis GC, Journal of surgical oncology 2021 Feb 123 2 606-613
- Patterns of Metastasis in Merkel Cell Carcinoma.
  Song Y, Azari FS, Tang R, Shannon AB, Miura JT, Fraker DL, Karakousis GC, Annals of surgical oncology 2021 Jan 28 1 519-529
- Does multicenter care impact the outcomes of surgical patients with gastrointestinal malignancies requiring complex multimodality therapy?
  Shannon AB, Mo J, Song Y, Paulson EC, Roses RE, Fraker DL, Kelz RR, Miura JT, Karakousis GC, Journal of surgical oncology 2020 Sep 122 4 729-738
- Predictors of lymph node metastases in patients with mucinous appendiceal adenocarcinoma.
  Shannon AB, Goldberg D, Song Y, Paulson EC, Roses RE, Fraker DL, Kelz RR, Miura J, Karakousis GC, Journal of surgical oncology 2020 Sep 122 3 399-406
- Sentinel lymph node positivity and overall survival in immunosuppressed patients with Merkel cell carcinoma: a national cohort study.
  Song Y, Zheng C, Shannon AB, Fraker DL, Miura JT, Karakousis GC, The British journal of dermatology 2020 Sep 183 3 569-571
- National trends in ventral hernia repairs for patients with intra-abdominal metastases.
  Song Y, Shannon AB, Roses RE, Fraker DL, Kelz RR, Karakousis GC, Surgery 2020 Sep 168 3 509-517
- Age and Melanocytic Lesions.
  Shannon AB, Song Y, Xu X, Karakousis GC, Surgical oncology clinics of North America 2020 Jul 29 3 369-386
- Can We Coach Resilience? An Evaluation of Professional Resilience Coaching as a Well-Being Initiative for Surgical Interns.
  Song Y, Swendiman RA, Shannon AB, Torres-Landa S, Khan FN, Williams NN, Dumon KR, Brooks AD, DeMatteo RP, Aarons CB, Journal of surgical education 2020 77 6 1481-1489

Research

Understanding the cancer metastatic niche
Novel therapies for melanoma and non-melanoma skin cancers
Prediction of treatment response following immunotherapy

Clinical Focus

Melanoma
Non-Melanoma Skin Cancers
Soft Tissue Tumors

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