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Publications
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Cardiac function surveillance practices and outcomes in patients with HER2-positive breast cancer treated with trastuzumab: a retrospective cohort study across a safety-net and tertiary care setting
Huang L, Manthena P, Su M, Chandra A, Sadeghi N Cardio-Oncology 2025 Dec 11 -
Global Longitudinal Strain: A Potential Noninvasive Tool for Early Detection of Radiation-Induced Cardiac Dysfunction in Patients With Lung Cancer Receiving Thoracic Radiation Therapy
Montalvo SK, Lue B, Kakadiaris E, Ahn C, Zhang-Velten E, Aliru M, Lu W, Westover KD, Iyengar P, Timmerman RD, Zaha VG, Vallabhaneni S, Zhang K, Chandra A, Alluri PG International Journal of Radiation Oncology Biology Physics 2025 Sep 123 221-227 -
Reduced Right Ventricular Size and Function in Adolescents and Adults Born Preterm
Blair ZW, Chandra A, Barton GP, Solano NS, Berry JD, Goss KN Journal of the American Society of Echocardiography 2025 Jul 38 615-623 -
Prevalence and Predictors of Subclinical Cardiomyopathy in Patients With Type 2 Diabetes in a Health System
Nagori A, Segar MW, Keshvani N, Patel L, Patel KV, Chandra A, Willett DW, Pandey A Journal of Diabetes Science and Technology 2025 May 19 699-704 -
Reframing the role of glucagon-like peptide 1 receptor agonists in cardiovascular medicine
Inciardi RM, Chandra A, Pandey A, Metra M ESC Heart Failure 2025 Apr 12 923-926 -
Immune Checkpoint Inhibitor Myocarditis and Left Ventricular Systolic Dysfunction
Author Collaboration II, Chen YC, Dolladille C, Rao A, Palaskas NL, Deswal A, Lehmann L, Cautela J, Courand PY, Hayek S, Zhu H, Cheng RK, Alexandre J, Baldassarre LA, Roubille F, Laufer-Perl M, Asnani A, Ederhy S, Tamura Y, Francis S, Gaughan EM, Johnson DB, Flint DL, Rainer PP, Bailly G, Ewer SM, Aras MA, Arangalage D, Cariou E, Florido R, Peretto G, Itzhaki Ben Zadok O, Akhter N, Narezkina A, Levenson JE, Liu Y, Crusz SM, Issa N, Piriou N, Leong D, Sandhu S, Turker I, Moliner P, Obeid M, Heinzerling L, Chang WT, Stewart A, Venkatesh V, Chandra A, Zhang KW, Zaha VG JACC: CardioOncology 2025 Apr 7 234-248 -
m-Health Based Cardiac Rehabilitation Program for Management of Older Patients With HFpEF: A Pilot RCT
Subramanian V, Betts T, Segar MW, Patel L, Keshvani N, Chandra A, Pandey A JACC: Heart Failure 2025 Apr 13 653-656 -
The RIGHT Way of Assessing Structural Changes Rather Than What Is LEFT Over?
Lee AY, Chandra A JACC: Asia 2024 Dec 4 938-939 -
Cardiac mechanics and the risk of atrial fibrillation in a community-based cohort of older adults
Inciardi RM, Wang W, Alonso A, Soliman EZ, Selvaraj S, Gonçalves A, Zhang MJ, Chandra A, Prasad NG, Skali H, Shah AM, Solomon SD, Chen LY European heart journal cardiovascular Imaging 2024 Dec 25 1686-1694 -
Clinical Correlates and Prognostic Impact of Cognitive Dysfunction in Patients with Heart Failure and Preserved Ejection Fraction: Insights from PARAGON-HF
Shen L, Dewan P, Ferreira JP, Cunningham JW, Jhund PS, Anand IS, Chandra A, Chiang LM, Claggett B, Desai AS, Gong J, Lam CS, Lefkowitz MP, Maggioni AP, Martinez F, Packer M, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, Solomon SD, McMurray JJ Circulation 2024 Dec 150 1913-1927 -
Fusobacterium necrophorum endocarditis with intracranial abscesses: A case report and review of the literature
Wong E, Robinson C, Upadhyaya P, Chandra A, Prokesch BC, Kang M Journal of Cardiology Cases 2024 Sep 30 75-78 -
Smaller Left Ventricular Size But Preserved Function in Adolescents and Adults Born Preterm
Barton GP, Chandra A, Sanchez-Solano N, Berry JD, Goss KN Journal of the American Heart Association 2024 Sep 13 -
Effect of Sacubitril/Valsartan on Cognitive Function in Patients With Heart Failure With Preserved Ejection Fraction: A Prespecified Analysis of PARAGON-HF
Dewan P, Shen L, Ferreira JP, Jhund PS, Anand IS, Chandra A, Chiang LM, Claggett B, Desai AS, Gong J, Lam CS, Lefkowitz MP, Maggioni AP, Martinez F, Packer M, Redfield MM, Rouleau JL, van Veldhuisen DJ, Zannad F, Zile MR, Solomon SD, McMurray JJ Circulation 2024 Jul 150 272-282 -
Temporal trends and racial/ethnic- and sex-differences in LDL cholesterol control among US adults with self-reported atherosclerotic cardiovascular disease
Nguyen DQ, Keshvani N, Chandra A, Alebna PL, Dixon DL, Shapiro MD, Michos ED, Sperling LS, Pandey A, Mehta A American Journal of Preventive Cardiology 2024 Jun 18 -
Association of Beta-Blocker Use With Exercise Capacity in Participants With Heart Failure With Preserved Ejection Fraction: A Post Hoc Analysis of the RELAX Trial
Patel L, Segar MW, Keshvani N, Subramanian V, Pandey A, Chandra A American Journal of Cardiology 2024 Apr 216 48-53 -
Association of diabetes-specific heart failure risk score with presence of subclinical cardiomyopathy among individuals with diabetes: A prospective study
Chunawala ZS, Keshvani N, Segar MW, Patel KV, Usman MS, Subramanian V, Raygor V, Chandra A, Khan MS, Pandey A European Journal of Heart Failure 2024 Mar 26 699-701 -
Cardiac Abnormalities in Hispanic/Latina Women with Prior de Novo Hypertensive Disorders of Pregnancy
Quesada O, Kulandavelu S, Vladutiu CJ, Defranco E, Minissian MB, Makarem N, Bello NA, Wong MS, Pabón MA, Chandra AA, Avilés-Santa L, Rodríguez CJ, Bairey Merz CN, Sofer T, Hurwitz BE, Talavera GA, Claggett BL, Solomon SD, Cheng S Hypertension 2024 Feb 81 255-263 -
Association of global longitudinal strain by feature tracking cardiac magnetic resonance imaging with adverse outcomes among community-dwelling adults without cardiovascular disease: The Dallas Heart Study
Subramanian V, Keshvani N, Segar MW, Kondamudi NJ, Chandra A, Maddineni B, Matulevicius SA, Michos ED, Lima JA, Berry JD, Pandey A European Journal of Heart Failure 2024 Feb 26 208-215 -
Novel Size-Based High-Density Lipoprotein Subspecies and Incident Vascular Events
Deets A, Joshi PH, Chandra A, Singh K, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RP, Gruppen EG, Connelly MA, Ayers C, Navar AM, Pandey A, Wilkins JT, Rohatgi A Journal of the American Heart Association 2023 Nov 12 -
Association of Dapagliflozin vs Placebo with Individual Kansas City Cardiomyopathy Questionnaire Components in Patients with Heart Failure with Mildly Reduced or Preserved Ejection Fraction: A Secondary Analysis of the DELIVER Trial
Peikert A, Chandra A, Kosiborod MN, Claggett BL, Desai AS, Jhund PS, Lam CS, Inzucchi SE, Martinez FA, De Boer RA, Hernandez AF, Shah SJ, Janssens SP, Bělohlávek J, Borleffs CJ, Dobreanu D, Langkilde AM, Bengtsson O, Petersson M, McMurray JJ, Solomon SD, Vaduganathan M JAMA Cardiology 2023 Jul 8 684-690 -
Impact of the Insoluble Gas Concentration on Measured Stroke Volume at Rest and Submaximal Exercise Using the Innocor Device
Reynolds E, Curry K, Barton G, Chandra A, Crandall CG, Berry JD Medicine and science in sports and exercise 2023 Mar 55 601-606 -
Identification and quantification of congestion in heart failure: a work in progress
Inciardi RM, Pellicori P, Chandra A European Journal of Heart Failure 2023 Jan 25 61-62 -
The Relationship of Alcohol Consumption and HDL Metabolism in the Multiethnic Dallas Heart Study
Badia RR, Pradhan RV, Ayers CR, Chandra A, Rohatgi A Journal of Clinical Lipidology 2023 Jan 17 124-130 -
Health-related quality of life outcomes in PARAGON-HF
Chandra A, Polanczyk CA, Claggett BL, Vaduganathan M, Packer M, Lefkowitz MP, Rouleau JL, Liu J, Shi VC, Schwende H, Zile MR, Desai AS, Pfeffer MA, McMurray JJ, Solomon SD, Lewis EF European Journal of Heart Failure 2022 Dec 24 2264-2274 -
Impact of Vitamin D3 Versus Placebo on Cardiac Structure and Function: A Randomized Clinical Trial
Chandra A, Picard MH, Huang S, Gupta DK, Agusala K, Buring JE, Lee IM, Cook NR, Manson JE, Thadhani RI, Wang TJ Journal of the American Heart Association 2022 Nov 11 -
Cardiovascular disease and chimeric antigen receptor cellular therapy
Rao A, Stewart A, Eljalby M, Ramakrishnan P, Anderson LD, Awan FT, Chandra A, Vallabhaneni S, Zhang K, Zaha VG Frontiers in Cardiovascular Medicine 2022 Sep 9 -
Gender Differences in Diagnosis, Prevention, and Treatment of Cardiotoxicity in Cardio-Oncology
Simek S, Lue B, Rao A, Ravipati G, Vallabhaneni S, Zhang K, Zaha VG, Chandra A Journal of Clinical Medicine 2022 Sep 11 -
Supranormal Left Ventricular Ejection Fraction, Stroke Volume, and Cardiovascular Risk: Findings From Population-Based Cohort Studies
Shah S, Segar MW, Kondamudi N, Ayers C, Chandra A, Matulevicius S, Agusala K, Peshock R, Abbara S, Michos ED, Drazner MH, Lima JA, Longstreth WT, Pandey A JACC: Heart Failure 2022 Aug 10 583-594 -
Epicardial adipose tissue in heart failure: risk factor or mediator?
Inciardi RM, Chandra A European Journal of Heart Failure 2022 Aug 24 1357-1358 -
Cardio-oncology imaging tools at the translational interface
Yaros K, Eksi B, Chandra A, Agusala K, Lehmann LH, Zaha VG Journal of Molecular and Cellular Cardiology 2022 Jul 168 24-32 -
Left Atrial Remodeling and Stroke in Patients With Sinus Rhythm and Normal Ejection Fraction: ARIC-NCS
Bianco F, De Caterina R, Chandra A, Aquila I, Claggett B, Johansen MC, Gonçalves A, Norby FL, Cogswell R, Soliman EZ, Gottesman R, Mosley T, Alonso A, Shah A, Solomon SD, Chen LY Journal of the American Heart Association 2022 May 11 -
Race- and Gender-Based Differences in Cardiac Structure and Function and Risk of Heart Failure
Chandra A, Skali H, Claggett B, Solomon SD, Rossi JS, Russell SD, Matsushita K, Kitzman DW, Konety SH, Mosley TH, Chang PP, Shah AM Journal of the American College of Cardiology 2022 Feb 79 355-368 -
Association of Myocardial Blood Flow Reserve with Adverse Left Ventricular Remodeling in Patients with Aortic Stenosis: The Microvascular Disease in Aortic Stenosis (MIDAS) Study
Zhou W, Sun YP, Divakaran S, Bajaj NS, Gupta A, Chandra A, Morgan V, Barrett L, Martell L, Bibbo CF, Hainer J, Lewis EF, Taqueti VR, Dorbala S, Blankstein R, Slomka P, Shah PB, Kaneko T, Adler DS, O'Gara P, Di Carli MF JAMA Cardiology 2022 Jan 7 93-99 -
Editorial commentary: Long COVID-19: A tangled web of lungs, heart, mind, and gender
Inciardi RM, Chandra A Trends in Cardiovascular Medicine 2022 Jan 32 18-19 -
Regional adiposity, cardiorespiratory fitness, and left ventricular strain: an analysis from the Dallas Heart Study
Kondamudi N, Thangada N, Patel KV, Ayers C, Chandra A, Berry JD, Neeland IJ, Pandey A Journal of Cardiovascular Magnetic Resonance 2021 Dec 23 -
Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis
Segar MW, Jaeger BC, Patel KV, Nambi V, Ndumele CE, Correa A, Butler J, Chandra A, Ayers C, Rao S, Lewis AA, Raffield LM, Rodriguez CJ, Michos ED, Ballantyne CM, Hall ME, Mentz RJ, De Lemos JA, Pandey A Circulation 2021 Jun 143 2370-2383 -
Differences in clinical characteristics and outcome of de novo heart failure compared to acutely decompensated chronic heart failure–systematic review and meta-analysis
Pranata R, Tondas AE, Yonas E, Vania R, Yamin M, Chandra A, Siswanto BB Acta Cardiologica 2021 76 410-420 -
Electronic health records⇓based cardio-oncology registry for care gap identification and pragmatic research: Procedure and observational study
Chandra A, Philips ST, Pandey A, Basit M, Kannan V, Sara EJ, Das SR, Lee SJ, Haley B, Willett DW, Zaha VG JMIR Cardio 2021 Jan 5 -
Effect of Doxorubicin on Myocardial Bicarbonate Production from Pyruvate Dehydrogenase in Women with Breast Cancer
Park JM, Reed GD, Liticker J, Putnam WC, Chandra A, Yaros K, Afzal A, MacNamara JP, Raza J, Hall RG, Baxter J, Derner K, Pena S, Kallem RR, Subramaniyan I, Edpuganti V, Harrison CE, Muthukumar A, Lewis C, Reddy S, Unni N, Klemow D, Syed S, Li H, Cole S, Froehlich T, Ayers C, De Lemos J, Malloy CR, Haley BB, Zaha VG Circulation research 2020 Dec 127 1568-1570 -
Associations Between Depressive Symptoms and HFpEF-Related Outcomes
Chandra A, Alcala MA, Claggett B, Desai AS, Fang JC, Heitner JF, Liu J, Pitt B, Solomon SD, Pfeffer MA, Lewis EF JACC: Heart Failure 2020 Dec 8 1009-1020 -
Using Simulation to Assess Cardiology Fellow Performance of Transthoracic Echocardiography: Lessons for Training in the COVID-19 Pandemic
Singh K, Chandra A, Lonergan K, Bhatt A Journal of the American Society of Echocardiography 2020 Nov 33 1421-1423 -
Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis
Singh K, Chandra A, Sperry T, Joshi PH, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RP, Gruppen EG, Connelly MA, Ayers CR, Rohatgi A Circulation 2020 Aug 142 657-669 -
Hypertensive coronary microvascular dysfunction: A subclinical marker of end organ damage and heart failure
Zhou W, Brown JM, Bajaj NS, Chandra A, Divakaran S, Weber B, Bibbo CF, Hainer J, Taqueti VR, Dorbala S, Blankstein R, Adler D, O'Gara P, Di Carli MF European heart journal 2020 Jul 41 2366-2375 -
Reply: Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction
Chandra A, Vaduganathan M, Lewis EF, Claggett B, McMurray JJ, Solomon SD JACC: Heart Failure 2020 Mar 8 245-246 -
Left atrial structure and function and the risk of death or heart failure in atrial fibrillation
Author Collaboration ob, Inciardi RM, Giugliano RP, Claggett B, Gupta DK, Chandra A, Ruff CT, Antman EM, Mercuri MF, Grosso MA, Braunwald E, Solomon SD European Journal of Heart Failure 2019 Dec 21 1571-1579 -
Longitudinal Associations between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study
Wang SY, Tan AS, Claggett B, Chandra A, Khatana SA, Lutsey PL, Kucharska-Newton A, Koton S, Solomon SD, Kawachi I JAMA Cardiology 2019 Dec 4 1203-1212 -
Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial
Author Collaboration PI, Chandra A, Vaduganathan M, Lewis EF, Claggett BL, Rizkala AR, Wang W, Lefkowitz MP, Shi VC, Anand IS, Ge J, Lam CS, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJ, Solomon SD JACC: Heart Failure 2019 Oct 7 862-874 -
The association of retinal vessel calibres with heart failure and long-term alterations in cardiac structure and function: the Atherosclerosis Risk in Communities (ARIC) Study
Chandra A, Seidelmann SB, Claggett BL, Klein BE, Klein R, Shah AM, Solomon SD European Journal of Heart Failure 2019 Oct 21 1207-1215 -
Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy
Vaduganathan M, Hirji SA, Qamar A, Bajaj N, Gupta A, Zaha VG, Chandra A, Haykowsky M, Ky B, Moslehi J, Nohria A, Butler J, Pandey A JACC: CardioOncology 2019 Sep 1 54-65 -
Temporal Changes in Body Fat Distribution and Hypertension
Chandra A, Ayers CR, Neeland IJ Journal of the American College of Cardiology 2019 Jul 73 3357-3359 -
Bleeding Risk in Patients with Cirrhosis Undergoing Transesophageal Echocardiography: 6-Year Experience from Parkland Health and Hospital System
Chandra A, Chen TC, Tang Z, Matulevicius SA, Das SR, Agrawal D Journal of the American Society of Echocardiography 2019 May 32 678-680 -
Intraventricular flow patterns during right ventricular apical pacing
Bianco F, Cicchitti V, Bucciarelli V, Chandra A, Di Girolamo E, Pedrizzetti G, Tonti G, Romano S, De Caterina R, Gallina S Open Heart 2019 May 6 -
Effects of sacubitril/valsartan on physical and social activity limitations in patients with heart failure, A secondary analysis of the PARADIGM-HF trial
Chandra A, Lewis EF, Claggett BL, Desai AS, Packer M, Zile MR, Swedberg K, Rouleau JL, Shi VC, Lefkowitz MP, Katova T, McMurray JJ, Solomon SD JAMA Cardiology 2018 Jun 3 498-505 -
Regional fat distribution and blood pressure level and variability
Yano Y, Vongpatanasin W, Ayers C, Turer AT, Chandra A, Carnethon MR, Greenland P, de Lemos JA, Neeland IJ Hypertension 2016 Sep 68 576-583 -
Relation of Black Race Between High Density Lipoprotein Cholesterol Content, High Density Lipoprotein Particles and Coronary Events (from the Dallas Heart Study)
Chandra A, Neeland IJ, Das SR, Khera A, Turer AT, Ayers CR, McGuire DK, Rohatgi AK American Journal of Cardiology 2015 Apr 115 890-894 -
Reply: Does body adiposity better predict obesity-associated cardiometabolic risk than body mass index?
Chandra A, Turer AT Journal of the American College of Cardiology 2015 Feb 65 633 -
The role of advanced lipid testing in the prediction of cardiovascular disease
Chandra A, Rohatgi A Current atherosclerosis reports 2014 Mar 16 -
The relationship of body mass and fat distribution with incident hypertension: Observations from the dallas heart study
Chandra A, Neeland IJ, Berry JD, Ayers CR, Rohatgi AK, Das SR, Khera A, McGuire DK, de Lemos JA, Turer AT Journal of the American College of Cardiology 2014 64 997-1002 -
Regionally selective atrophy after traumatic axonal injury
Warner MA, Youn TS, Davis T, Chandra A, Marquez De La Plata C, Moore C, Harper C, Madden CJ, Spence J, McColl R, Devous M, King RD, Diaz-Arrastia R Archives of neurology 2010 Nov 67 1336-1344
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Cardiac function surveillance practices and outcomes in patients with HER2-positive breast cancer treated with trastuzumab: a retrospective cohort study across a safety-net and tertiary care setting
Alvin Chandra, M.D.
- Internal Medicine - Cardiology
- Cardio-Oncology
- Advanced Heart Failure with Preserved Ejection Fraction
New Patient Appointment Accepting Virtual Visits or 214-645-8000
Biography
Alvin Chandra, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center.
Dr. Chandra received his initial medical training at UT Southwestern, where he earned his medical degree, performed an internal medicine residency, and completed a general cardiology fellowship. During residency, he was awarded the Best Research Article by an Internal Medicine Resident at UT Southwestern. He then received advanced training in cardio-oncology through an additional fellowship at Dana-Farber Cancer Institute, followed by a research fellowship in cardiovascular imaging at Brigham and Women’s Hospital and Harvard Medical School.
Certified by the American Board of Internal Medicine, he returned to UT Southwestern, joining the faculty in 2019.
Dr. Chandra is a cardiologist and echocardiographer whose clinical and research interests focus on heart failure with preserved ejection fraction (HFpEF), cardiovascular imaging, and cardio-oncology. He serves as Director of the Cardiometabolic Research Unit Echo Core Laboratory and Director of the Cancer Center Echo Lab, where he oversees echocardiographic imaging for clinical programs and research studies, including the Dallas Heart Study. He also serves as the site principal investigator for several clinical trials. In 2022, he received the Ware Family Clinical Research Award at UT Southwestern.
Dr. Chandra is a Fellow of the American College of Cardiology. He has served as a reviewer for several journals, including Circulation, European Heart Journal, and Journal of the American College of Cardiology. He is Co-Chair of the Cardio-Oncology Section of the Texas Chapter of the American College of Cardiology and serves as an assistant editor for JACC: CardioOncology. Dr. Chandra has authored more than 60 peer-reviewed publications.
Personal Note
His interests outside of cardiology include spending time with his family, pickleball, the Texas Longhorns, and fantasy football.
Education & Training
- Medical School - UT Southwestern Medical School (2008-2012)
- Residency - UT Southwestern Medical Center (2012-2015), Internal Medicine
- Fellowship - UT Southwestern Medical Center (2015-2017), Cardiology
- Fellowship - Brigham and Women's Hospital (2017-2019), Cardiac Imaging
Books & Publications
Clinical Focus
- Cardio-Oncology
- Advanced Heart Failure with Preserved Ejection Fraction
Cardio-Oncology Clinic
at Cancer Care Outpatient Building 6202 Harry Hines Blvd., 7th FloorDallas, Texas 75235 (214) 645-4673 Directions to Cardio-Oncology Clinic at Cancer Care Outpatient Building, Dallas Parking Info for Cardio-Oncology Clinic
New Patient Appointment Accepting Virtual Visits or 214-645-8000