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Antonia Chen, M.D.

  • Dr. Charles F. Gregory Distinguished Chair in Orthopaedic Surgery
  • Orthopaedic Surgery
  • Total Knee Replacement
  • Total Hip Replacement

Appointment New Patient Appointment or 214-645-3300

Appointment New Patient Appointment or 214-645-3300

Biography

Antonia F. Chen, M.D., M.B.A., is a Professor and Chair of the Department of Orthopaedic Surgery at UT Southwestern Medical Center. She specializes in primary and revision total knee and hip replacement surgeries and partial knee replacements, as well as total joint replacement infection management. She holds the Dr. Charles F. Gregory Distinguished Chair in Orthopaedic Surgery.

Dr. Chen earned her medical degree at Rutgers’ Robert Wood Johnson Medical School in New Brunswick, New Jersey. She also earned a master’s in business administration at Rutgers Business School. She then completed a residency in orthopaedic surgery at the University of Pittsburgh and received advanced training through an adult reconstruction fellowship at the Rothman Institute in Philadelphia.

Certified by the American Board of Orthopaedic Surgery, she joined the UT Southwestern faculty in 2024. She previously served as an Associate Professor at Harvard Medical School and was Chief of Arthroplasty and Joint Reconstruction and Director of Research for the Arthroplasty Service at Brigham and Women's Hospital in Boston.

Dr. Chen holds significant editorial roles with several academic journals. She sits on the editorial boards of the Journal of Arthroplasty, the Journal of Bone and Joint Infection, and the Journal of Orthopaedic Research; is a Deputy Editor for the Journal of Bone and Joint Surgery; and is an Associate Editor for Arthroplasty Today. She also holds leadership positions in national organizations such as the American Academy of Orthopaedic Surgeons and the American Association of Hip and Knee Surgeons, for which she is currently second Vice President. She also serves on UT Southwestern’s ASC Strategy Steering Committee.

She has served as a principal investigator (PI) on several grants, including studies examining the role of vitamin D in joint arthroplasty outcomes and the use of decision-making aids to reduce racial disparities in joint replacement surgeries. She also served as Site PI for a large multicenter trial comparing venous thromboembolism prevention strategies after hip and knee replacements, supported by the Agency for Healthcare Research and Quality.

Dr. Chen has authored several books, including Management of Orthopaedic Infections: A Practical Guide, The Little Ortho Book: The Bare Bones of Orthopedics, and Quick Reference Dictionary for Orthopedics, and she has contributed chapters to more than 50 other books. She has delivered scores of invited lectures and published more than 400 peer-reviewed articles related to her areas of expertise.

The recipient of numerous awards, she earned the Nancy J. Tarbell Dean's Leadership Award for an Emerging Leader in Women's Careers in 2024. The award is given by the Joint Committee on the Status of Women at Harvard Medical School and Harvard School of Dental Medicine.

Personal Note

When she’s not at work, Dr. Chen enjoys spending time with her family, dog, and friends; riding her Peloton; hiking; and road biking.

Professional Associations & Affiliations
  • American Academy of Orthopaedic Surgeons
  • American Association of Hip and Knee Surgeons
  • American Orthopaedic Association
  • The Association of Bone and Joint Surgeons
  • European Knee Associates
  • European Society of Sports Traumatology, Knee Surgery and Arthroscopy
  • Musculoskeletal Infection Society
  • Orthopaedic Research Society
  • Ruth Jackson Orthopaedic Society
  • The Hip Society
  • The Knee Society
Honors & Awards
  • Dr. Charles F. Gregory Distinguished Chair in Orthopaedic Surgery 2024, UT Southwestern
  • Nancy J. Tarbell Dean's Leadership Award for an Emerging Leader in Women's Careers 2024, Joint Committee on the Status of Women at Harvard Medical School and Harvard School of Dental Medicine
  • Michael A. Bell Family Distinguished Chair in Healthcare Innovation 2024, Brigham and Women’s Hospital
  • Mentor Award 2024, Brigham and Women’s Hospital
  • Top 1% of Orthopedic Research All-Stars for 2024 2024, Avant-Garde Health
  • Highly Ranked Scholar 2024, ScholarGPS
  • Exceptional Women in Medicine Award 2021-2024, Castle Connolly
  • Top Doctor Award 2021-2024, Boston Magazine
  • Women Empowerment Award 2023, American Association of Hip and Knee Surgeons
  • Presidential Fellows Program 2023, Brigham and Women’s Hospital
  • Outstanding Mentor Award 2023, Massachusetts General Hospital/Brigham and Women’s Hospital
  • Research Highlights 2023, Springer Nature
  • Poster Award – Primary Hip 2022, American Association of Hip and Knee Surgeons
  • Honoree 2022, Helio Honors
  • She-For-She Award – Nominee 2022, Ruth Jackson Orthopaedic Society
  • Excellence in Student Mentoring Award 2021, Harvard Medical School Scholarly Engagement
  • Poster Award – Non-arthroplasty and Miscellaneous 2021, American Association of Hip and Knee Surgeons
  • Resident Research Award 2021, Brigham and Women’s Hospital
  • Best Poster Award in Practice Management 2021, American Academy of Orthopaedic Surgeons
  • Harris Award 2021, Orthopaedic Research Society
  • Golden Award of the 1st Academic Paper Contest for Better Arthroplasty 2021, Arthroplasty Society in Asia
  • Poster Award – Infection 2020, American Association of Hip and Knee Surgeons
  • Poster Award – Primary Hip 2020, American Association of Hip and Knee Surgeons
  • John N. Insall Knee Traveling Fellowship 2019
  • Current Concepts in Joint Replacement/Orthopaedic Research Education Foundation Award, 2018, 2019
  • The Otto Aufranc Award 2019, Hip Society Meeting
  • American-British-Canadian Traveling Fellowship 2019, American Orthopaedic Association
  • Partners in Excellence Teamwork Award 2019, Brigham and Women’s Hospital
  • Nesson Award for Collaboration 2019, Brigham and Women’s Hospital
  • Elite Reviewer Status 2019, Journal of Bone and Joint Surgery
  • Top Peer Reviewer 2019, Publons Global Peer Review Awards
Books & Publications
  • Books
    • The PCL-sparing total knee arthroplasty in The Cruciate Ligaments in Total Knee Arthroplasty
      Franco JR, Chen AF (2024)
    • Anterolateral approach in Revision Hip Arthroplasty
      Kobyashi A, Chen AF (2024)
    • Aseptic loosening in Revision Hip Arthroplasty
      Martinez R, Chen AF (2024)
    • Direct lateral in Revision Hip Arthroplasty
      Lim PL, Chen AF, Melnic CM (2024)
    • Reducing opioid use in orthopaedic surgery in Instructional Course Lectures. Vol 74.
      Horneff JG, Abboud JA, Chen AF, Ilyas A (2024), Rosemont, IL, Wolters Kluwer Health
    • Revision total hip arthroplasty due to limb length discrepancy in Revision Hip Arthroplasty
      Morcos MM, Farid AR, Chen AF, Shah VM (2024)
    • Irrigants and irrigation in Musculoskeletal Infection 2
      Rubenstein W, Chen AF (2023), Rosemont, IL, Wolters Kluwer Health
    • Assessment of functional motion of the pelvis and femur in Special Considerations for Orthopedic and Spine Surgeons Treating Hip-Spine Syndrome
      Vajapey SP, Chen AF (2023), Cambridge Scholars Publishing
    • Multi-modal pain control and ERAS/rapid recovery protocols for DAA in The Direct Anterior Approach to Hip Reconstruction (2nd ed.)
      Roy AE, Chen AF, Shah VM (2023), Wolters Kluwer, Inc.
    • Antibiotics and cement in Complications in Orthopaedic Surgery: Adult Reconstruction
      Lee E, Chen AF (2022), United Kingdom, Elsevier Publishing
    • Infection risk in Evaluation and Management of Hip and Knee Arthritis in Women
      Lu L, Chen AF (2022), Philadelphia, PA, Elsevier Publishing
    • Cardiopulmonary disease and arthroplasty in Optimized Patient Care in the Perioperative Management of Hip and Knee Arthroplasty
      Lamanna D, Chen AF (2022)
    • Hip osteoarthritis in Taking Care of You: The Empowered Woman’s Guide to Health
      Liu C, Chen AF (2022), United States, Mayo Clinic Press
    • Cooled radiofrequency ablation as a treatment for knee osteoarthritis in Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics
      Chen AF, Moorhead EJ (2022), United Kingdom, Elsevier Publishing
    • Knee replacement: Clinical perspectives in Joint Replacement Technology
      Blaha JD, Chen AF (2021), Elsevier
    • Modifiable risk factor optimization prior to total joint replacement in Instructional Course Lectures
      Egan C, Chen AF (2021), Wolters Kluwer
    • Evidence-based quality and outcomes assessment in pediatric orthopaedics in Orthopaedic Knowledge Update Pediatrics 6
      Chen AF, Roberts KC, Shea KG, Mehlman CT, Quinn RH, Beckmann JT (2021), Wolters Kluwer
    • Management of Orthopaedic Infections: A Practical Guide (1st ed.)
      Chen AF (2021), Thieme
    • Surgical site infection risk reduction in Quality Improvement and Patient Safety in Orthopedic Surgery
      Antonelli B, Chen AF (2022), United States, Springer Nature
    • Clinical practice guidelines and appropriate use criteria to guide care in Quality Improvement and Patient Safety in Orthopedic Surgery
      Brown GA, Chen AF (2022), United States, Springer Nature
    • Mini-open approach to the hip in Hip Arthroscopy and Hip Joint Preservation Surgery (2nd ed.)
      Yacovelli S, Chen AF, O’Toole P, Minori J, Parvizi J (2022), USA, Springer
    • Antibiotic-loaded bone cement in Essentials of Cemented Knee Arthroplasty
      Hosseinzadeh S, Gorman H, Chen AF (2021), India, Springer Nature
    • Orthopedic surgery in Current Diagnosis and Treatment Surgery (15th ed.)
      Chen AF (2020), United States, McGraw Hill
    • Statistical Reasoning for Surgeons
      Maltenfort MG, Restrepo C, Chen AF (2020), Taylor & Francis Ltd.
    • Antimicrobial materials in arthroplasty in Racing for the Surface
      Shaner J, Hickok N, Chen AF (2020), Switzerland, Springer Publishing
    • Infection prophylaxis in TKA in Basics in Primary Knee Arthroplasty
      Eizember SC, Kazarian ER, Chen AF (2019), USA, Springer Publishing
    • How to avoid typical complications after total knee arthroplasty in Basics in Primary Knee Arthroplasty
      Fraser JF, Chen AF (2019), USA, Springer Publishing
    • Acetabular dysplasia in The Adult Hip – Master Case Series and Techniques
      Kenanidis E, Kakoulidis P, Tsiridis E, Atilla B, Bicanic G, Sulje Z, Delimar D, Bondarenko S, Filippenko V, et al. (2018), Switzerland, Springer International Publishing
    • Proximal femoral dysplasia in The Adult Hip – Master Case Series and Techniques
      Kenanidis E, Kakoulidis P, Tsiridis E, Dundon J, Vigdorchik J, Chen AF, Rothman RH (2018), Switzerland, Springer International Publishing
    • Greater wound and renal complications in gout patients undergoing total joint arthroplasty in Wounds: Background, Principles, and Recent Research and Clinical Techniques
      Shields MV, Chen AF (2017)
    • Biofilm-related infections: Orthopaedic considerations and implications in World Clinics
      Hickok NJ, Shapiro IM, Chen AF, Parvizi J, Harwood M (2017), USA
    • New potential biomarkers for musculoskeletal disease: Extracellular vesicle (exosomes) analysis in World Clinics
      Shapiro IM, Chen AF, Freeman T, Hickok N (2017), USA
    • Degenerative knee pathology in Grauer Orthopaedic Knowledge Update (OKU) 12
      Chen AF, Parvizi J (2016), USA, American Academy of Orthopaedic Surgeons (AAOS)
    • Orthopedic implant use and infection in Comprehensive Biomaterials (2nd ed.)
      Antoci V, Chen AF, Parvizi J (2016), USA, Elsevier Publishing
    • The Little Ortho Book: The Bare Bones of Orthopedics. Chinese edition.
      Chen AF (2016), Ho-Chi Publishing Co.
    • Special perioperative management: Orthopedic surgery in Patient Blood Management: Multidisciplinary Approaches to Optimizing Care (2nd ed.)
      Chen AF, Klatt BA (2016), USA, American Association of Blood Banks
    • The incidence and socioeconomic impact of periprosthetic joint infection: United States perspective in Periprosthetic Joint Infections: Changing Paradigms
      Gutowski C, Chen AF, Parvizi J (2016), USA, Springer
    • Who is at risk for PJI? in Periprosthetic Joint Infections: Changing Paradigms
      Tan TL, Kheir MM, Chen AF (2016), USA, Springer
    • Preoperative antibiotics in Rothman Arthroplasty Algorithm Book
      Chen AF, Parvizi J (2016), USA, Jaypee Publishers
    • Postoperative fluid management in Rothman Arthroplasty Algorithm Book
      Wu MH, Chen AF, Parvizi J (2016), USA, Jaypee Publishers
    • Optimization of renal failure in Rothman Arthroplasty Algorithm Book
      Tan TL, Filippone EJ, Chen AF (2016), USA, Jaypee Publishers
    • Oxygen desaturation management in Rothman Arthroplasty Algorithm Book
      Viola JR, Chen AF, Hozack WJ (2016), USA, Jaypee Publishers
    • Management of acute infection – knee in Rothman Arthroplasty Algorithm Book
      Küçükdurmaz F, Chen AF, Parvizi J (2016), USA, Jaypee Publishers
    • TKA associated infections – Treatment strategies in Total Knee Arthroplasty – A Comprehensive Guide
      Manrique J, Gomez MM, Chen AF, Parvizi J (2016), USA, Springer
    • Anatomy – Cartilage in Advances in Hip Arthroscopy
      Ulici V, Chen AF, Cheng A, Tuan RS (2016), USA, Springer
    • Results of arthroplasty in post-traumatic arthritis in Post-Traumatic Arthritis: Pathogenesis, Diagnosis, and Management
      Chen AF, Parvizi J (2015), USA, Springer
    • Surgical technique: Mini-open approach in Hip Arthroscopy and Hip Joint Preservation Surgery
      Chen AF, O’Toole P, Minori J, Parvizi J (2015), USA, Springer
    • Surgical technique: Mini-open acetabular rim trimming and labral refixation/femoral osteochondroplasty in Hip Arthroscopy and Hip Joint Preservation Surgery
      O’Toole P, Chen AF, Minori J, Parvizi J (2015), USA, Springer
    • Prevention of infection in The Hip: Preservation, Replacement, and Revision
      Chen AF (2015), USA, Data Trace Publishing Company
    • Micro-grooved surface topography does not influence fretting corrosion of tapers in THA: Classification and retrieval analysis in Modularity and Tapers in Total Joint Replacement Devices
      Arnholt C, Underwood R, MacDonald DW, Higgs G, Chen AF, Klein G, Hamlin B, Lee G, Mont M, Cates H, Malkani A, Kraay M, Rimnac C, Kurtz SM (2015)
    • Is taper fretting corrosion a threat to the clinical performance of large-diameter hips with HXLPE bearings? in Modularity and Tapers in Total Joint Replacement Devices
      Kurtz SM, MacDonald DW, Gilbert JL, Mont MA, Klein G, Chen AF, Kraay M, Hamlin B, Rimnac CM (2015)
    • Arthritis in Orthopaedic Knowledge Update (OKU) 11
      Klatt BA, Chen AF, Tuan RS (2014), USA, American Academy of Orthopaedic Surgeons
    • Above knee amputation in Periprosthetic Joint Infection
      Chen AF, Fedorka CJ, Klatt BA (2014), USA, SLACK Incorporated
    • The Little Ortho Book: The Bare Bones of Orthopedics
      Chen AF (2014), New Jersey, SLACK Inc.
    • Position and orientation of the stem in Primary Total Hip Replacement
      Chen AF, Tischler EH, Austin MS (2013), Italy, Minerva Medica
    • Orthopaedic fellowship application process in How to Get Into Orthopedic Residency in the US
      Chen AF (2013), USA, Jaypee Brothers Medical Publishers
    • TKA in patients with organ transplantation in Knee Reconstruction, Replacement and Revision
      Klatt BA, Chen AF (2012), USA, Data Trace Publishing Company
    • Preoperative clinical evaluation in Knee Reconstruction, Replacement and Revision
      Farber NJ, Chen AF, Klatt BA (2012), USA, Data Trace Publishing Company
    • Cervical whiplash in Decision Making in Spine Care (2nd ed.)
      Braly BA, Chen AF, Woods B, Syed IY, Lee JY (2012), USA, Thieme Medical Publishers
    • Quick Reference Dictionary for Orthopedics
      Chen AF (2012), New Jersey, SLACK Incorporated
    • Hip arthroscopy in Master Techniques in Orthopaedic Surgery: Sports Medicine
      Wright V and Chen AF (2010), USA, Lippincott Williams & Wilkins
    • ACL injuries and treatment in The Knee: A Comprehensive Review
      Chen AF, Schreiber VM, van Eck CF, Fu FH (2010), Singapore, World Scientific Publishing Co.
Research
  • Patient optimization prior to joint replacement
  • Patient outcomes after joint replacement
  • Periprosthetic joint infection
  • Arthrofibrosis (joint stiffness)

Clinical Focus

  • Total Knee Replacement
  • Total Hip Replacement
  • Partial Knee Replacement
  • Robotic Joint Replacement
  • Total Joint Replacement Infection

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Appointment New Patient Appointment or 214-645-3300