- Medical School - Northwestern University Feinberg School of Medicine (2001-2005)
- Internship - University of Michigan Health System (2005-2006), General Surgery
- Postdoctoral Fellowship - Stanford University (2009-2011), Pediatrics & Medical Genetics
- Residency - University of Michigan Health System (2006-2013), Plastic & Reconstructive Surgery
- Other Post Graduate Training - Massachusetts General Hospital
- Fellowship - Massachusetts General Hospital (2013-2014), Surgical Critical Care
Benjamin Levi, M.D.
- Dr. Lee Hudson-Robert R. Penn Chair in Surgery
- Surgery - Burn, Trauma, Acute and Critical Care Surgery
- Burn Reconstructive Surgery
- Scar Reconstructive Surgery
Benjamin Levi, M.D., is an Associate Professor in the Department of Surgery at UT Southwestern Medical Center. He holds the Dr. Lee Hudson-Robert R. Penn Chair in Surgery and Plastic and Reconstructive Surgery and serves as Division Chief of Burn, Trauma, Acute and Critical Care Surgery. He specializes in acute and reconstructive burn surgery and scar reconstructive surgery.
Dr. Levi earned his medical degree at the Northwestern University Feinberg School of Medicine. He completed a residency in plastic and reconstructive surgery at the University of Michigan Hospital. He received advanced training through a research fellowship in pediatric regenerative medicine at Stanford University and a clinical fellowship in surgical critical care and burn surgery at Massachusetts General Hospital and Shriners Hospitals for Children – Boston.
Certified by the American Board of Plastic Surgery and the American Board of Surgery, Dr. Levi joined the UT Southwestern faculty in 2020. Previously, he was Director of the Burn/Wound and Regenerative Medicine Laboratory and Associate Director of Burn Surgery Service at the University of Michigan.
Dr. Levi’s research interests, which are funded by the National Institutes of Health, the American College of Surgeons, and the Department of Defense, include stem cell biology, heterotopic ossification, muscle fibrosis, tissue regeneration, wound healing and repair, and burn reconstruction outcomes.
He is the author of more than 100 scholarly articles, including high-impact papers in Science Translational Medicine, Proceedings of the National Academy of Sciences, and Nature Communications, as well as chapters in a number of textbooks, including Greenfield’s Surgery, Total Burn Care, Grabb and Smith’s Plastic Surgery, and Trauma. He has delivered presentations worldwide, held numerous invited professorships, and serves as a permanent editor and ad hoc editor for journals in his area of research.
Dr. Levi co-chairs the Reconstructive Special Interest Group of the American Burn Association. He is also a member of the American College of Surgeons, the American Council of Academic Plastic Surgeons, the American Society for Bone and Mineral Research, the American Society of Plastic Surgeons, the Association for Academic Surgery, the Reed O. Dingman Society, and the Plastic Surgery Research Council.
- American Burn Association
- American College of Surgeons
- American Council of Academic Plastic Surgeons
- American Society for Bone and Mineral Research
- American Society of Plastic Surgeons
- Association for Academic Surgery
- Reed O. Dingman Society
- Plastic Surgery Research Council
- American Society for Bone and Mineral Research (ASBMR) Fuller Albright Award 2019
- George H.A. Clowes Award 2018, American College of Surgeons
- Young Investigator Award 2018, The American Society for Clinical Investigation
- Academic Scholarship Award 2017, American Association of Plastic Surgery
- First Inaugural AAS Plastic Surgery Young Investigator Award 2016, Association for Academic Surgery
- Bernard G. Sarnat Excellence in Grant Writing Award 2016, Plastic Surgery Foundation
- George H.A. Clowes Career Development Award 2015, American College of Surgeons
- Joan L. and Julius H. Jacobson II Promising Investigator Award 2015, American College of Surgeons
- Academic Scholarship Award 2015, American Association of Plastic Surgery
- Research & Education Foundation Scholarship 2015, American Association for the Surgery of Trauma
Advancements in Cortical Bone Imaging – Trabecular and Cortical Bone: Morphology, Biomechanics and Clinical Implications
Donneys A, Nelson N, Ahsan S, Peterson JR, Morris MD, Esmonde-White F, Buchman SR, Wang SC, Levi B. Ed Varsha Subramaniam and Manish Bhatnagar (2014), New York, Nova Biomedical
Management of Acute Thermal Injury in Evidence- Based Critical Care: A Case Study Approach
Ranganathan K, Wang S, Levi B. Ed. Robert C. Hyzy (2017), Cham, Springer
Importance of mineral and bone metabolism after burn in Total Burn Care
Levi B, Lisiecki J, Klein G. Ed. David Herndon (2018), Elsevier
Face Burn Reconstruction (Cheek, Nose, Lip) in Global Reconstructive Surgery
Peterson J, Levi B, Lisiecki J. Ed. James Chang (2019), Elsevier
Burns in Fitzpatrick’s Dermatology Ed. 9 Vol. 2
Levi B, Wang S. Ed. Sewon Kang (2019), McGraw and Hill
Burn Surgery in Greenfield’s Surgery Ed 8.
Levi B, Hemmila M, Wang SC (In Press)
Burn Surgery and Critical Care in Massachusetts General Hospital Critical Care Handbook, Ed. 2
Levi B, Wong VC, Sheridan R (In Press)
Burns in Trauma Ed. 9
Vercruysse G, Levi B (2020 - In Press), McGraw and Hill
- Advancements in Cortical Bone Imaging – Trabecular and Cortical Bone: Morphology, Biomechanics and Clinical Implications
Treatment of heterotopic ossification through remote ATP hydrolysis.
Peterson JR, De La Rosa S, Eboda O, Cilwa KE, Agarwal S, Buchman SR, Cederna PS, Xi C, Morris MD, Herndon DN, Xiao W, Tompkins RG, Krebsbach PH, Wang SC, Levi B, Science translational medicine 2014 Sep 6 255 255ra132
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
Agarwal S, Loder SJ, Brownley C, Eboda O, Peterson JR, Hayano S, Wu B, Zhao B, Kaartinen V, Wong VC, Mishina Y, Levi B, Developmental biology 2015 Apr 400 2 202-9
Surgical Excision of Heterotopic Ossification Leads to Re-Emergence of Mesenchymal Stem Cell Populations Responsible for Recurrence.
Agarwal S, Loder S, Cholok D, Li J, Breuler C, Drake J, Brownley C, Peterson J, Li S, Levi B, Stem cells translational medicine 2017 03 6 3 799-806
Characterizing the Circulating Cell Populations in Traumatic Heterotopic Ossification.
Loder SJ, Agarwal S, Chung MT, Cholok D, Hwang C, Visser N, Vasquez K, Sorkin M, Habbouche J, Sung HH, Peterson J, Fireman D, Ranganathan K, Breuler C, Priest C, Li J, Bai X, Li S, Cederna PS, Levi B, The American journal of pathology 2018 11 188 11 2464-2473
Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing.
Sorkin M, Huber AK, Hwang C, Carson WF, Menon R, Li J, Vasquez K, Pagani C, Patel N, Li S, Visser ND, Niknafs Y, Loder S, Scola M, Nycz D, Gallagher K, McCauley LK, Xu J, James AW, Agarwal S, Kunkel S, Mishina Y, Levi B, Nature communications 2020 02 11 1 722
Dura mater stimulates human adipose-derived stromal cells to undergo bone formation in mouse calvarial defects.
Levi B, Nelson ER, Li S, James AW, Hyun JS, Montoro DT, Lee M, Glotzbach JP, Commons GW, Longaker MT, Stem cells (Dayton, Ohio) 2011 Aug 29 8 1241-55
CD105 protein depletion enhances human adipose-derived stromal cell osteogenesis through reduction of transforming growth factor ß1 (TGF-ß1) signaling.
Levi B, Wan DC, Glotzbach JP, Hyun J, Januszyk M, Montoro D, Sorkin M, James AW, Nelson ER, Li S, Quarto N, Lee M, Gurtner GC, Longaker MT, The Journal of biological chemistry 2011 Nov 286 45 39497-509
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.
Levi B, Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC, Weissman IL, Wan DC, Longaker MT, Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 109 50 20379-84
Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells.
Peterson JR, Eboda O, Agarwal S, Ranganathan K, Buchman SR, Lee M, Wang SC, Mishina Y, Levi B, Stem cells translational medicine 2014 Nov 3 11 1375-80
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Agarwal S, Loder SJ, Sorkin M, Li S, Shrestha S, Zhao B, Mishina Y, James AW, Levi B, Stem cells (Dayton, Ohio) 2016 06 34 6 1692-701
Local and Circulating Endothelial Cells Undergo Endothelial to Mesenchymal Transition (EndMT) in Response to Musculoskeletal Injury.
Agarwal S, Loder S, Cholok D, Peterson J, Li J, Fireman D, Breuler C, Hsieh HS, Ranganathan K, Hwang C, Drake J, Li S, Chan CK, Longaker MT, Levi B, Scientific reports 2016 09 6 32514
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, Gardenier J, Hsieh HH, Wang SC, Mehrara BJ, Levi B, Annals of surgery 2016 Dec 264 6 1174-1180
Inhibition of Hif1a prevents both trauma-induced and genetic heterotopic ossification.
Agarwal S, Loder S, Brownley C, Cholok D, Mangiavini L, Li J, Breuler C, Sung HH, Li S, Ranganathan K, Peterson J, Tompkins R, Herndon D, Xiao W, Jumlongras D, Olsen BR, Davis TA, Mishina Y, Schipani E, Levi B, Proceedings of the National Academy of Sciences of the United States of America 2016 Jan 113 3 E338-47
Evaluation of Salivary Cytokines for Diagnosis of both Trauma-Induced and Genetic Heterotopic Ossification.
Sung Hsieh HH, Chung MT, Allen RM, Ranganathan K, Habbouche J, Cholok D, Butts J, Kaura A, Tiruvannamalai-Annamalai R, Breuler C, Priest C, Loder SJ, Li J, Li S, Stegemann J, Kunkel SL, Levi B, Frontiers in endocrinology 2017 8 74
Scleraxis-Lineage Cells Contribute to Ectopic Bone Formation in Muscle and Tendon.
Agarwal S, Loder SJ, Cholok D, Peterson J, Li J, Breuler C, Cameron Brownley R, Hsin Sung H, Chung MT, Kamiya N, Li S, Zhao B, Kaartinen V, Davis TA, Qureshi AT, Schipani E, Mishina Y, Levi B, Stem cells (Dayton, Ohio) 2017 03 35 3 705-710
Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification.
Agarwal S, Loder SJ, Breuler C, Li J, Cholok D, Brownley C, Peterson J, Hsieh HH, Drake J, Ranganathan K, Niknafs YS, Xiao W, Li S, Kumar R, Tompkins R, Longaker MT, Davis TA, Yu PB, Mishina Y, Levi B, Molecular therapy : the journal of the American Society of Gene Therapy 2017 08 25 8 1974-1987
Harnessing macrophage-mediated degradation of gelatin microspheres for spatiotemporal control of BMP2 release.
Annamalai RT, Turner PA, Carson WF, Levi B, Kunkel S, Stegemann JP, Biomaterials 2018 04 161 216-227
Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification.
Hwang C, Marini S, Huber AK, Stepien DM, Sorkin M, Loder S, Pagani CA, Li J, Visser ND, Vasquez K, Garada MA, Li S, Xu J, Hsu CY, Yu PB, James AW, Mishina Y, Agarwal S, Li J, Levi B, Bone research 2019 7 36
Coordinating Tissue Regeneration Through Transforming Growth Factor-ß Activated Kinase 1 Inactivation and Reactivation.
Hsieh HHS, Agarwal S, Cholok DJ, Loder SJ, Kaneko K, Huber A, Chung MT, Ranganathan K, Habbouche J, Li J, Butts J, Reimer J, Kaura A, Drake J, Breuler C, Priest CR, Nguyen J, Brownley C, Peterson J, Ozgurel SU, Niknafs YS, Li S, Inagaki M, Scott G, Krebsbach PH, Longaker MT, Westover K, Gray N, Ninomiya-Tsuji J, Mishina Y, Levi B, Stem cells (Dayton, Ohio) 2019 06 37 6 766-778
Nonintegrating knockdown and customized scaffold design enhances human adipose-derived stem cells in skeletal repair.
Levi B, Hyun JS, Nelson ER, Li S, Montoro DT, Wan DC, Jia FJ, Glotzbach JC, James AW, Lee M, Huang M, Quarto N, Gurtner GC, Wu JC, Longaker MT, Stem cells (Dayton, Ohio) 2011 Dec 29 12 2018-29
- Treatment of heterotopic ossification through remote ATP hydrolysis.
- Stem Cell Biology
- Heterotopic Ossification
- Tissue Regeneration
- Wound Healing and Repair
- Burn Reconstruction
- Muscle Fibrosis
- Burn Reconstructive Surgery
- Scar Reconstructive Surgery
- Acute Burn Surgery
- Surgical Critical Care