- Fellowship - UT Southwestern Medical Center (2000-2001), Neuromuscular Disease
- Residency - UT Southwestern Medical Center (1997-2000), Neurology
- Residency - Overlook Hospital (1995-1997), Internal Medicine
- Residency - Seth Kanaiyalal Motilal (1993-1995), Internal Medicine
- Internship - Seth Kanaiyalal Motilal (1992-1993), Internal Medicine
- Medical School - Smt. N.H.L. Municipal Medical College, India
Jaya Trivedi, M.D.
Medical Director of Ambulatory Neurology, UTSW Medical Center
- Neuromuscular Disorders
Jaya Trivedi, M.D., is a Professor in the Department of Neurology at UT Southwestern Medical Center. She specializes in treating neuromuscular disorders.
Dr. Trivedi received her M.B.B.S. from Smt. N.H.L. Municipal Medical College in India. She completed internal medicine residencies at Sheth K.M. School of P.G. Medicine & Research in India and at Overlook Hospital in New Jersey before joining UT Southwestern, where she performed a residency in neurology and a fellowship in neuromuscular medicine.
Dr. Trivedi holds a number of departmental leadership positions, including Medical Director of Ambulatory Neurology, Fellowship Director of Neuromuscular Disorders, and Associate Division Chief of Neuromuscular Medicine.
She is a Fellow of the American Neurological Association and the American Academy of Neurology and a member of the Dallas County Medical Society and the Texas Medical Association. In addition, she serves on the medical advisory board of the Periodic Paralysis Association.
Meet Dr. Trivedi
Neurologist in Dallas
Jaya Trivedi, M.D., has dedicated her career to treating challenging neurological conditions; she has particular expertise at caring for patients with neuromuscular disorders.
Dr. Trivedi specializes in treating conditions such as amytrophic lateral sclerosis (ALS), myasthenia gravis, chronic inflammatory demyelinating polyneuropathy (CIPD), peripheral neuropathy, inflammatory myopathies, and muscular dystrophy.
“I enjoy my work and love taking care of patients,” Dr. Trivedi says. “Some of their disorders can be challenging to treat, but we take on the challenges together.”
Patients travel from around the country to see Dr. Trivedi for a rare category of conditions called muscle channelopathies. These include myotonia congenita, paramyotonia congenita, and periodic paralysis. Through her clinical research and experience with her patients, Dr. Trivedi is now known as one of the experts in the country specializing in muscle channelopathies.
Challenging Disorders Treated Compassionately
Because so many of the conditions Dr. Trivedi treats have no cure, like ALS, much of her patient care includes symptomatic treatment and support.
For autoimmune neuromuscular disorders, such as CIDP, inflammatory myopathies or myasthenia gravis, she treats patients with chronic immunosuppressive therapy that requires rigorous monitoring to make sure they aren’t developing complications.
“Lifelong conditions such as periodic paralysis can be very disabling,” Dr. Trivedi says. “You can use medications to reduce the number of a patient’s paralysis attacks, but you can’t abolish attacks altogether. Often, it’s also about modifying patient’s lifestyle to reduce the paralytic episodes.
Dr. Trivedi and her colleagues at UT Southwestern have also been involved with a number of multi-center clinical trials that resulted in treatments now in common use.
“We’re always searching for new treatments,” Dr. Trivedi says. “New treatments can help patients with neuromuscular disorders lead a better-quality life with fewer symptoms.”
- Member, American Association of Neuromuscular & Electrodiagnostic Medicine
- Member, American Academy of Neurology
- Outstanding Resident 1997, Achievement in Clinical Science & Humanism in the Practice of Medicine
- Senior Resident of the Year 2000, From Staff of Acute Stroke Unit/Epilepsy Monitoring Unit at PMH, Dallas, Tx
- Trephined Cranium Teaching Award 2003, From residents, Department of Neurology
Clinical Review of Muscle-Specific Tyrosine Kinase-Antibody Positive Myasthenia Gravis.
Wolfe G.I., Trivedi J.R., Oh S.J. Journal of Clinical Neuromuscular Disease 2007 8 217-224
Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis.
Nieves JW, Gennings C, Factor-Litvak P, Hupf J, Singleton J, Sharf V, Oskarsson B, Fernandes Filho JA, Sorenson EJ, D'Amico E, Goetz R, Mitsumoto H, JAMA neurology 2016 Dec 73 12 1425-1432
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study.
Howard JF, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Muppidi S, Nowak RJ, O'Brien F, Wang JJ, Mantegazza R The Lancet. Neurology 2017 Oct
Transverse myelitis in systemic sclerosis.
Torabi AM, Patel RK, Wolfe GI, Hughes CS, Mendelsohn DB, Trivedi JR Archives of neurology 2004 Jan 61 1 126-8
Primary episodic ataxias: diagnosis, pathogenesis and treatment.
Jen JC, Graves TD, Hess EJ, Hanna MG, Griggs RC, Baloh RW, Brain : a journal of neurology 2007 Oct 130 Pt 10 2484-93
Clinical findings in MuSK-antibody positive myasthenia gravis: a U.S. experience.
Pasnoor M, Wolfe GI, Nations S, Trivedi J, Barohn RJ, Herbelin L, McVey A, Dimachkie M, Kissel J, Walsh R, Amato A, Mozaffar T, Hungs M, Chui L, Goldstein J, Novella S, Burns T, Phillips L, Claussen G, Young A, Bertorini T, Oh S Muscle & nerve 2010 Mar 41 3 370-4
An interactive voice response diary for patients with non-dystrophic myotonia.
Statland JM, Wang Y, Richesson R, Bundy B, Herbelin L, Gomes J, Trivedi J, Venance S, Amato A, Hanna M, Griggs R, Barohn RJ, Muscle & nerve 2011 Jul 44 1 30-5
Huntington chorea presenting with motor neuron disease.
Sadeghian H, O'Suilleabhain PE, Battiste J, Elliott JL, Trivedi JR Archives of neurology 2011 May 68 5 650-2
Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of the novel enzyme replacement therapy avalglucosidase alfa (neoGAA) in treatment-naïve and alglucosidase alfa-treated patients with late-onset Pompe disease: A phase 1, open-label, multicenter, multinational, ascending dose study.
Pena LDM, Barohn RJ, Byrne BJ, Desnuelle C, Goker-Alpan O, Ladha S, Laforêt P, Mengel KE, Pestronk A, Pouget J, Schoser B, Straub V, Trivedi J, Van Damme P, Vissing J, Young P, Kacena K, Shafi R, Thurberg BL, Culm-Merdek K, van der Ploeg AT, Neuromuscular disorders : NMD 2019 03 29 3 167-186
Health-related quality-of-life improvements in CIDP with immune globulin IV 10%: the ICE Study.
Merkies IS, Bril V, Dalakas MC, Deng C, Donofrio P, Hanna K, Hartung HP, Hughes RA, Latov N, van Doorn PA, Neurology 2009 Apr 72 15 1337-44
Electrophysiology in chronic inflammatory demyelinating polyneuropathy with IGIV.
Bril V, Katzberg H, Donofrio P, Banach M, Dalakas MC, Deng C, Hanna K, Hartung HP, Hughes RA, Latov N, Merkies IS, van Doorn PA, Muscle & nerve 2009 Apr 39 4 448-55
Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS.
Benatar M, Zhang L, Wang L, Granit V, Statland J, Barohn R, Swenson A, Ravits J, Jackson C, Burns TM, Trivedi J, Pioro EP, Caress J, Katz J, McCauley JL, Rademakers R, Malaspina A, Ostrow LW, Wuu J, Neurology 2020 May
Von hippel-lindau disease associated with thymoma and myasthenia gravis.
Sheth MN, Nations SP, Wolfe GI, Trivedi JR Journal of clinical neuromuscular disease 2005 Dec 7 2 59-61
A quantitative measure of handgrip myotonia in non-dystrophic myotonia.
Statland JM, Bundy BN, Wang Y, Trivedi JR, Raja Rayan D, Herbelin L, Donlan M, McLin R, Eichinger KJ, Findlater K, Dewar L, Pandya S, Martens WB, Venance SL, Matthews E, Amato AA, Hanna MG, Griggs RC, Barohn RJ Muscle & nerve 2012 Oct 46 4 482-9
Mexiletine for symptoms and signs of myotonia in nondystrophic myotonia: a randomized controlled trial.
Statland JM, Bundy BN, Wang Y, Rayan DR, Trivedi JR, Sansone VA, Salajegheh MK, Venance SL, Ciafaloni E, Matthews E, Meola G, Herbelin L, Griggs RC, Barohn RJ, Hanna MG JAMA : the journal of the American Medical Association 2012 Oct 308 13 1357-65
Nondystrophic myotonia: Challenges and future directions.
Trivedi JR, Cannon SC, Griggs RC Experimental neurology 2014 Mar 253 28-30
Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.
Sansone VA, Burge J, McDermott MP, Smith PC, Herr B, Tawil R, Pandya S, Kissel J, Ciafaloni E, Shieh P, Ralph JW, Amato A, Cannon SC, Trivedi J, Barohn R, Crum B, Mitsumoto H, Pestronk A, Meola G, Conwit R, Hanna MG, Griggs RC Neurology 2016 Feb
Trends in authorship based on gender and nationality in published neuroscience literature.
Dubey D, Sawhney A, Atluru A, Amritphale A, Dubey A, Trivedi J, Neurology India 2016 Jan-Feb 64 1 97-100
Intravenous immune globulin (10% caprylate-chromatography purified) for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (ICE study): a randomised placebo-controlled trial.
Hughes RA, Donofrio P, Bril V, Dalakas MC, Deng C, Hanna K, Hartung HP, Latov N, Merkies IS, van Doorn PA, The Lancet. Neurology 2008 Feb 7 2 136-44
Correlates of quality of life in ALS: Lessons from the minocycline study.
Lou JS, Moore D, Gordon PH, Miller R, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2010 11 1-2 116-21
NORTH AMERICA AND SOUTH AMERICA (NA-SA) NEUROPATHY PROJECT.
Pasnoor M, Nascimento O, Trivedi J, Wolfe G, Nations S, Herbelin L, Freitas M, Quintanilha G, Khan S, Dimachkie M, Barohn R The International journal of neuroscience 2013 Mar
Editorial by concerned physicians: Unintended effect of the Orphan Drug Act on the potential cost of 3,4-diaminopyridine.
Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, De Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Sheih PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI Muscle & nerve 2015 Dec
A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression.
Weiss MD, Macklin EA, Simmons Z, Knox AS, Greenblatt DJ, Atassi N, Graves M, Parziale N, Salameh JS, Quinn C, Brown RH, Distad JB, Trivedi J, Shefner JM, Barohn RJ, Pestronk A, Swenson A, Cudkowicz ME, Neurology 2016 Apr 86 16 1474-81
Primary Lateral Sclerosis: Clinical and Laboratory Features in 25 Patients.
Singer MA, Kojan S, Barohn RJ, Herbelin L, Nations SP, Trivedi JR, Jackson CE, Burns DK, Boyer PJ, Wolfe GI Journal of clinical neuromuscular disease 2005 Sep 7 1 1-9
Treatment and management of neuromuscular channelopathies.
Sharp L, Trivedi JR Current treatment options in neurology 2014 Oct 16 10 313
Hereditary and Acquired Polyneuropathy Conditions of the Peripheral Nerves: Clinical Considerations and MR Neurography Imaging.
Trivedi JR, Phillips L, Chhabra A Seminars in musculoskeletal radiology 2015 Apr 19 2 130-6
Non-dystrophic myotonia: prospective study of objective and patient reported outcomes.
Trivedi JR, Bundy B, Statland J, Salajegheh M, Rayan DR, Venance SL, Wang Y, Fialho D, Matthews E, Cleland J, Gorham N, Herbelin L, Cannon S, Amato A, Griggs RC, Hanna MG, Barohn RJ Brain : a journal of neurology 2013 Jul 136 Pt 7 2189-200
Statland J, Phillips L, Trivedi JR Neurologic clinics 2014 Aug 32 3 801-815
The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment.
Matthews E, Fialho D, Tan SV, Venance SL, Cannon SC, Sternberg D, Fontaine B, Amato AA, Barohn RJ, Griggs RC, Hanna MG Brain : a journal of neurology 2010 Jan 133 Pt 1 9-22
Long-term safety and efficacy of eculizumab in generalized myasthenia gravis.
Muppidi S, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Nowak RJ, Andersen H, Casasnovas C, De Bleecker JL, Vu TH, Mantegazza R, O'Brien FL, Wang JJ, Fujita KP, Howard JF Muscle & nerve 2019 Feb
Eculizumab improves fatigue in refractory generalized myasthenia gravis.
Andersen H, Mantegazza R, Wang JJ, O'Brien F, Patra K, Howard JF, Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2019 Mar
Guidelines on clinical presentation and management of non-dystrophic myotonias.
Stunnenberg B, LoRusso S, Arnold WD, Barohn RJ, Cannon SC, Fontaine B, Griggs RC, Hanna MG, Matthews E, Meola G, Sansone VA, Trivedi JR, van Engelen B, Vicart S, Statland JM, Muscle & nerve 2020 Apr
Skeletal Muscle Channelopathies.
Phillips L, Trivedi JR Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2018 Oct
Excellent response to therapeutic plasma exchange in myasthenia gravis patients irrespective of antibody status.
Usmani A, Kwan L, Wahib-Khalil D, Trivedi J, Nations S, Sarode R Journal of clinical apheresis 2019 Feb
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, ShankaracharyaSmith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L, Moreno CAM, Kamalakaran S, Goldstein DB, Gitler AD, Harris T, Myers RM, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Coope Neuron 2018 Mar 97 6 1268-1283.e6
Treatment of painful peripheral neuropathy.
Trivedi JR, Silvestri NJ, Wolfe GI Neurologic clinics 2013 May 31 2 377-403
Denture cream: an unusual source of excess zinc, leading to hypocupremia and neurologic disease.
Nations SP, Boyer PJ, Love LA, Burritt MF, Butz JA, Wolfe GI, Hynan LS, Reisch J, Trivedi JR Neurology 2008 Aug 71 9 639-43
Effect of Mexiletine on Muscle Stiffness in Patients With Nondystrophic Myotonia Evaluated Using Aggregated N-of-1 Trials.
Stunnenberg BC, Raaphorst J, Groenewoud HM, Statland JM, Griggs RC, Woertman W, Stegeman DF, Timmermans J, Trivedi J, Matthews E, Saris CGJ, Schouwenberg BJ, Drost G, van Engelen BGM, van der Wilt GJ, JAMA 2018 12 320 22 2344-2353
Adult polyglucosan body disease associated with lewy bodies and tremor.
Trivedi JR, Wolfe GI, Nations SP, Burns DK, Bryan WW, Dewey RB Archives of neurology 2003 May 60 5 764-6
Painful peripheral neuropathy and its nonsurgical treatment.
Wolfe GI, Trivedi JR Muscle & nerve 2004 Jul 30 1 3-19
Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery.
Gwinn K, Corriveau RA, Mitsumoto H, Bednarz K, Brown RH, Cudkowicz M, Gordon PH, Hardy J, Kasarskis EJ, Kaufmann P, Miller R, Sorenson E, Tandan R, Traynor BJ, Nash J, Sherman A, Mailman MD, Ostell J, Bruijn L, Cwik V, Rich SS, Singleton A, Refolo L, Andrews J, Zhang R, Conwit R, Keller MA, PloS one 2007 Dec 2 12 e1254
Review of the Diagnosis and Treatment of Periodic Paralysis.
Statland JM, Fontaine B, Hanna MG, Johnson NE, Kissel JT, Sansone VA, Shieh PB, Tawil RN, Trivedi J, Cannon SC, Griggs RC, Muscle & nerve 2018 04 57 4 522-530
- Clinical Review of Muscle-Specific Tyrosine Kinase-Antibody Positive Myasthenia Gravis.
- Myotonic disorders
- Myasthenia Gravis
- Ischemic Monomelic Neuropathy
- Andersen-Tawil syndrome
- Amyotrophic Lateral Sclerosis
- Neuromuscular Disorders