- Fellowship - University of Pennsylvania Perelman School of Medicine (2013-2016), Gastroenterology
- Residency - New York University School of Medicine (2009-2013), Internal Medicine
- Medical School - Northwestern University Feinberg School of Medicine (2005-2009)

Josephine Ni, M.D.
- Internal Medicine - Digestive and Liver Diseases
- Gastroenterology
- Microbiology
Biography
Josephine Ni, M.D., is an Assistant Professor in the Departments of Internal Medicine and Microbiology at UT Southwestern Medical Center. She is a gastroenterologist who focuses on the treatment of inflammatory bowel diseases.
Dr. Ni earned her medical degree at Northwestern University and completed a residency in internal medicine at New York University, where she served as a chief resident. She received advanced training in gastroenterology through a fellowship at the University of Pennsylvania, where she continued as faculty until 2021.
Board certified in internal medicine and gastroenterology, she joined the UT Southwestern faculty in 2021.
Dr. Ni is a physician-scientist. Her research explores bacterial colonization of the healthy and inflamed intestinal tract with the goal of modulating the gut microbiota to treat intestinal diseases. She is a recipient of the American Gastroenterological Association-Takeda Research Scholar Award in Inflammatory Bowel Disease, and her current research is funded by the NIH as well as a Career Award for Medical Scientists from the Burroughs Wellcome Fund. She is the author of multiple publications and has been invited to speak both nationally and internationally on her research.
Dr. Ni is a member of the American Gastroenterological Association and the Crohn’s and Colitis Foundation.
Education & Training
Professional Associations & Affiliations
- American Gastroenterological Association
- Crohn’s and Colitis Foundation
Honors & Awards
- Career Award for Medical Scientists 2020-2025, Burroughs Wellcome Fund
- Research Scholar Award in Inflammatory Bowel Disease 2017-2020, American Gastroenterological Association-Takeda
- Frank Brooks Research Award in Gastroenterology 2016, Perelman School of Medicine/University of Pennsylvania
- Intern of the Year Award 2010, New York University Department of Medicine
Books & Publications
-
Publications
-
Engineering the gut microbiota to treat hyperammonemia.
Shen TC, Albenberg L, Bittinger K, Chehoud C, Chen YY, Judge CA, Chau L, Ni J, Sheng M, Lin A, Wilkins BJ, Buza EL, Lewis JD, Daikhin Y, Nissim I, Yudkoff M, Bushman FD, Wu GD, The Journal of clinical investigation 2015 Jul 125 7 2841-50 -
Dietary Regulation of the Gut Microbiota Engineered by a Minimal Defined Bacterial Consortium.
Shen TC, Chehoud C, Ni J, Hsu E, Chen YY, Bailey A, Laughlin A, Bittinger K, Bushman FD, Wu GD, PloS one 2016 11 5 e0155620 -
A role for bacterial urease in gut dysbiosis and Crohn's disease.
Ni J, Shen TD, Chen EZ, Bittinger K, Bailey A, Roggiani M, Sirota-Madi A, Friedman ES, Chau L, Lin A, Nissim I, Scott J, Lauder A, Hoffmann C, Rivas G, Albenberg L, Baldassano RN, Braun J, Xavier RJ, Clish CB, Yudkoff M, Li H, Goulian M, Bushman FD, Lewis JD, Wu GD Science translational medicine 2017 Nov 9 416 -
Improved Long-term Outcomes of Patients With Inflammatory Bowel Disease Receiving Proactive Compared With Reactive Monitoring of Serum Concentrations of Infliximab.
Papamichael K, Chachu KA, Vajravelu RK, Vaughn BP, Ni J, Osterman MT, Cheifetz AS, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2017 Oct 15 10 1580-1588.e3 -
Gut microbiota and IBD: causation or correlation?
Ni J, Wu GD, Albenberg L, Tomov VT, Nature reviews. Gastroenterology & hepatology 2017 Oct 14 10 573-584 -
Bacterial colonization reprograms the neonatal gut metabolome.
Bittinger K, Zhao C, Li Y, Ford E, Friedman ES, Ni J, Kulkarni CV, Cai J, Tian Y, Liu Q, Patterson AD, Sarkar D, Chan SHJ, Maranas C, Saha-Shah A, Lund P, Garcia BA, Mattei LM, Gerber JS, Elovitz MA, Kelly A, DeRusso P, Kim D, Hofstaedter CE, Goulian M, Li H, Bushman FD, Zemel BS, Wu GD, Nature microbiology 2020 06 5 6 838-847 -
Intubation difficulties in a patient with an esophageal foreign body.
Goudra BG, Kronish K, Wong S, Ni J, Journal of clinical anesthesia 2014 Mar 26 2 160-1 -
Risk for Post-Colonoscopy Irritable Bowel Syndrome in Patients With and Without Antibiotic Exposure: A Retrospective Cohort Study.
Vajravelu RK, Shapiro JM, Ni J, Thanawala SU, Lewis JD, El-Serag HB, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021 Sep -
Randomized controlled-feeding study of dietary emulsifier carboxymethylcellulose reveals detrimental impacts on the gut microbiota and metabolome.
Chassaing B, Compher C, Bonhomme B, Liu Q, Tian Y, Walters W, Nessel L, Delaroque C, Hao F, Gershuni V, Chau L, Ni J, Bewtra M, Albenberg L, Bretin A, McKeever L, Ley RE, Patterson AD, Wu GD, Gewirtz AT, Lewis JD, Gastroenterology 2021 Nov
-
Engineering the gut microbiota to treat hyperammonemia.
Clinical Focus
- Gastroenterology
- Microbiology