Matthew Porembka, M.D.

Matthew Porembka, M.D.

  • Dedman Family Scholar in Clinical Care
  • Surgery - Surgical Oncology
  • Gallbladder/Bile Duct (Cholangiocarcinoma) Cancer
  • Liver Cancer


Matthew Porembka, M.D., is an Associate Professor of Surgical Oncology in the Department of Surgery at UT Southwestern Medical Center. He treats patients with liver, pancreas, stomach, and bile duct cancers.

After receiving his undergraduate degree at Johns Hopkins University, Dr. Porembka earned his medical degree at the University of Pittsburgh School of Medicine. He completed his general surgery internship and residency at Washington University/Barnes-Jewish Hospital. He then performed a research fellowship in tumor immunology at Washington University/Barnes-Jewish Hospital and a fellowship in complex general surgical oncology at Memorial Sloan Kettering Cancer Center.

Board certified by the American Board of Surgery, Dr. Porembka became a UT Southwestern faculty member in 2014, where he was named a Dedman Family Scholar in Clinical Care. 

Dr. Porembka's previous recognitions and awards include the Kristen Ann Carr Traveling Fellowship in 2014, and the Eugene M. Bricker Teaching Award in 2012, which he received while serving the second of two years as the Administrative Chief Resident at Washington University.

He has published numerous articles and presented invited lectures both regionally and nationally. 

Dr. Porembka is a Fellow of the American College of Surgeons, as well as a member of the Society of Surgical Oncology and the Association for Academic Surgery.

Personal Note

Dr. Porembka is married to a radiologist, and they have a son and daughter.

Meet Dr. Porembka

Surgical Oncologist in Dallas

Surgical oncologist Matthew Porembka, M.D., serves as the quarterback on the medical team for his patients with liverpancreasstomach, or bile duct cancers. The entire team works together to make decisions, but Dr. Porembka takes special pride in guiding his patients through their treatment process and beyond.

Dr. Porembka is at the forefront of the newest advancements in treating cancer and providing personalized cancer care, which includes extracting a tumor, analyzing it for genetic changes, and targeting highly specific treatment based on the mutations. This personalized treatment is a leading-edge method of care that was developed nearly a decade ago but in some ways is still in its infancy.

“We have learned a lot of information about genetic changes found in different cancers through projects like the Cancer Genome Atlas,” he says. “The challenge now is finding the optimal way to use this information in our patients to obtain the best outcomes.”

Because of the complexity of cancer, Dr. Porembka also focuses on helping patients understand what to expect from their treatment and answering any questions they may have.

“My relationship with patients doesn’t end when they get better from their surgery. I’m there to help with care coordination, surveillance, and dealing with any issues that come up later,” he says.

“When patients leave my office, I want them to feel like they can focus on themselves and their families because we are taking care of everything else.”

Fellowship-trained in tumor immunology and complex general surgical oncology, Dr. Porembka is also a Dedman Family Scholar in Clinical Care, an endowed program focused on bringing talented clinician-scientists to UT Southwestern early in their careers.

With the program’s funding, Dr. Porembka centers his research on stomach cancer (also known as gastric cancer) to better characterize tumors and personalize treatment.

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Education & Training
  • Fellowship - Memorial Sloan-Kettering Cancer Center (2012-2014), Surgical Oncology
  • Residency - Washington University/Barnes Jewish Hospital (2005-2012), General Surgery
  • Medical School - University of Pittsburgh School of Medicine (2001-2005)
Honors & Awards
  • D Magazine Best Doctor 2020-2022

Clinical Focus

  • Gallbladder/Bile Duct (Cholangiocarcinoma) Cancer
  • Liver Cancer
  • Pancreatic Cancer
  • Stomach/EG Junction Cancer
  • Gastrointestinal Cancers
  • Pancreatic Disease
  • Gallbladder & Bile Duct Disease

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Dr. Matthew Porembka

Dr. Porembka talks about his approach to patient care.