- Medical School - Ohio State University College of Medicine & Public Health (2007-2011)
- Residency - UT Southwestern Medical Center (2011-2014), Internal Medicine
- Fellowship - UT Southwestern Medical Center (2017-2018), Transplant Hepatology
- Fellowship - UT Southwestern Medical Center (2014-2017), Gastroenterology
Nicole Rich, M.D.
- Internal Medicine - Digestive and Liver Diseases
New Patient Appointment Accepting Virtual Visits or 214-645-8300
Nicole Rich, M.D., M.S.C.S., is an Assistant Professor of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Digestive and Liver Diseases. Her clinical interests include the management of advanced liver disease and liver cancer.
Originally from Canton, Ohio, Dr. Rich graduated magna cum laude from Case Western Reserve University with bachelor's degrees in biology and psychology. She earned her medical degree at the Ohio State University in Columbus, and completed internal medicine residency training at UT Southwestern, where she also completed advanced training through fellowship programs in gastroenterology (NIH T32 research track) and in transplant hepatology. She also holds a master's degree in clinical sciences from UT Southwestern.
Certified by the American Board of Internal Medicine in internal medicine, gastroenterology, and transplant hepatology, she joined the UT Southwestern faculty in 2018.
Dr. Rich's research is focused on understanding and identifying mechanisms contributing to racial, ethnic, gender, and socioeconomic disparities in outcomes among patients with chronic liver disease and hepatocellular carcinoma (HCC), the most common type of liver cancer. She has published numerous articles on the topic of HCC, with a focus on health disparities and care delivery, in various peer-reviewed journals including Gastroenterology, Hepatology, Clinical Gastroenterology & Hepatology, and Gut. She serves as co-investigator for several NIH-funded and Cancer Prevention and Research Institute of Texas (CPRIT) grants. In 2020, she was awarded the Texas Health Resources Clinical Scholar Award to develop a comprehensive population health research program focused on reducing disparities in liver disease in North Texas. Most recently, she received a career development award from the American College of Gastroenterology to investigate biological and behavioral mechanisms underlying sex and gender disparities in HCC.
Dr. Rich is active in several professional organizations, including the American Gastroenterological Association, American College of Gastroenterology, International Liver Cancer Association, American Society of Transplantation, and the American Association for the Study of Liver Diseases, which she serves as a member of the Online Learning Committee. She also serves on the United Network for Organ Sharing (UNOS) Adult HCC National Liver Review Board.
At UT Southwestern, Dr. Rich is a member of the Harold C. Simmons Comprehensive Cancer Center, and participates in the Liver Tumor program and the multidisciplinary HCC clinic.
Education & Training
Books & Publications
Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis.
Tzartzeva K, Obi J, Rich NE, Parikh ND, Marrero JA, Yopp A, Waljee AK, Singal AG Gastroenterology 2018 05 154 6 1706-1718.e1
Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis.
Rich NE, Oji S, Mufti AR, Browning JD, Parikh ND, Odewole M, Mayo H, Singal AG Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018 Feb 16 2 198-210.e2
Racial and Ethnic Differences in Presentation and Outcomes of Hepatocellular Carcinoma.
Rich NE, Hester C, Odewole M, Murphy CC, Parikh ND, Marrero JA, Yopp AC, Singal AG Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018 May
Hepatocellular Carcinoma Incidence is Decreasing Among Younger Adults in the United States.
Rich NE, Yopp AC, Singal AG, Murphy CC, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2019 Apr
Comparative Analysis of Nonalcoholic Steatohepatitis- Versus Viral Hepatitis- and Alcohol-Related Liver Disease-Related Hepatocellular Carcinoma.
Hester CA, Rich NE, Singal AG, Yopp AC, Journal of the National Comprehensive Cancer Network : JNCCN 2019 Apr 17 4 322-329
Direct-Acting Antiviral Therapy for HCV Infection is Associated with Increased Survival in Patients With a History of Hepatocellular Carcinoma.
Singal AG, Rich NE, Mehta N, Branch A, Pillai A, Hoteit M, Volk M, Odewole M, Scaglione S, Guy J, Said A, Feld JJ, John BV, Frenette C, Mantry P, Rangnekar AS, Oloruntoba O, Leise M, Jou JH, Bhamidimarri KR, Kulik L, Ioannou GN, Huang A, Tran T, Samant H, Dhanasekaran R, Duarte-Rojo A, Salgia R, Eswaran S, Jalal P, Flores A, Satapathy SK, Kagan S, Gopal P, Wong R, Parikh ND, Murphy CC, Gastroenterology 2019 Jul
Randomized Clinical Trial of Inreach With or Without Mailed Outreach to Promote Hepatitis C Screening in a Difficult-to-Reach Patient Population.
Desai N, Rich NE, Jain MK, Blackwell JM, Murphy CC, Perryman P, McBryde J, Quirk L, Clark C, Villarreal D, Waljee AK, Gopal P, Singal AG, The American journal of gastroenterology 2020 Dec Publish Ahead of Print
Racial and Ethnic Disparities in Survival Among Patients With Hepatocellular Carcinoma in the United States: A Systematic Review and Meta-Analysis.
Rich NE, Carr C, Yopp AC, Marrero JA, Singal AG, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020 Dec
Hepatocellular carcinoma demonstrates heterogeneous growth patterns in a multi-center cohort of patients with cirrhosis.
Rich NE, John BV, Parikh ND, Rowe I, Mehta N, Khatri G, Thomas SM, Anis M, Mendiratta-Lala M, Hernandez C, Odewole M, Sundaram LT, Konjeti VR, Shetty S, Shah T, Zhu H, Yopp AC, Hoshida Y, Yao FY, Marrero JA, Singal AG, Hepatology (Baltimore, Md.) 2020 Feb
Sex disparities in presentation and prognosis of 1110 patients with hepatocellular carcinoma.
Rich NE, Murphy CC, Yopp AC, Tiro J, Marrero JA, Singal AG, Alimentary pharmacology & therapeutics 2020 Jun
"Raising HOPE": Improved Outcomes for HIV/HCV-coinfected Liver Transplant Recipients in the Direct-acting Antiviral Era.
Cotter TG, Wang J, Lieber SR, Odenwald MA, Rich NE, Marrero JA, Singal AG, Mitchell MC, Aronsohn A, Charlton M, Fung J, Transplantation direct 2021 Jul 7 7 e707
Systematic review with meta-analysis: recurrence of hepatocellular carcinoma following direct-acting antiviral therapy.
Saraiya N, Yopp AC, Rich NE, Odewole M, Parikh ND, Singal AG Alimentary pharmacology & therapeutics 2018 Jul 48 2 127-137
Uncovering Biological Factors That Regulate Hepatocellular Carcinoma Growth Using Patient-Derived Xenograft Assays.
Zhu M, Li L, Lu T, Yoo H, Zhu J, Gopal P, Wang SC, Porembka MR, Rich NE, Kagan S, Odewole M, Renteria V, Waljee AK, Wang T, Singal AG, Yopp AC, Zhu H, Hepatology (Baltimore, Md.) 2020 09 72 3 1085-1101
Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis.
Sanchez JI, Jiao J, Kwan SY, Veillon L, Warmoes MO, Tan L, Odewole M, Rich NE, Wei P, Lorenzi PL, Singal AG, Beretta L, Cancer prevention research (Philadelphia, Pa.) 2021 Jul
Dynamic Changes in Ultrasound Quality for Hepatocellular Carcinoma Screening in Patients with Cirrhosis.
Schoenberger H, Chong N, Fetzer DT, Rich NE, Yokoo T, Khatri G, Olivares J, Parikh ND, Yopp AC, Marrero JA, Singal AG, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021 Jun
Patient and provider-level barriers to hepatitis C screening and linkage to care: A mixed-methods evaluation.
Higashi RT, Jain MK, Quirk L, Rich NE, Waljee AK, Turner BJ, Lee SC, Singal AG, Journal of viral hepatitis 2020 07 27 7 680-689
Evaluation of a multifaceted intervention to reduce health disparities in hepatitis C screening: a pre-post analysis.
Jain MK, Rich NE, Ahn C, Turner BJ, Sanders JM, Adamson B, Quirk L, Perryman P, Santini NO, Singal AG, Hepatology (Baltimore, Md.) 2019 Apr
State-Level HCC Incidence and Association With Obesity and Physical Activity in the United States.
Lee YT, Wang JJ, Luu M, Tseng HR, Rich NE, Lu SC, Nissen NN, Noureddin M, Singal AG, Yang JD, Hepatology (Baltimore, Md.) 2021 Mar
Medical Management of Hepatocellular Carcinoma.
Rich NE, Yopp AC, Singal AG Journal of oncology practice 2017 Jun 13 6 356-364
Pro: Liver Transplantation Should Be Considered in Select Patients With Acute Alcoholic Hepatitis.
Kubiliun MJ, Rich NE, Singal A, Mufti AR, Clinical liver disease 2019 May 13 5 140-143
LI-RADS treatment response algorithm after first-line DEB-TACE: reproducibility and prognostic value at initial post-treatment CT/MRI.
Pirasteh A, Sorra EA, Marquez H, Sibley RC, Fielding JR, Vij A, Rich NE, Arroyo A, Yopp AC, Khatri G, Singal AG, Yokoo T, Abdominal radiology (New York) 2021 Mar
High Neutrophil-Lymphocyte Ratio and Delta Neutrophil-Lymphocyte Ratio Are Associated with Increased Mortality in Patients with Hepatocellular Cancer.
Rich NE, Parvathaneni A, Sen A, Odewole M, Arroyo A, Mufti AR, Kerr TA, Grant L, Tujios SR, Mayo MJ, Lee WM, Yang JD, Yokoo T, Gopal P, Hoshida Y, Zhu H, Yopp AC, Marrero JA, Singal AG, Digestive diseases and sciences 2021 May
Role of imaging in management of hepatocellular carcinoma: surveillance, diagnosis, and treatment response.
Osho A, Rich NE, Singal AG, Hepatoma research 2020 6
Malignant infiltration of the liver presenting as acute liver failure.
Rich NE, Sanders C, Hughes RS, Fontana RJ, Stravitz RT, Fix O, Han SH, Naugler WE, Zaman A, Lee WM Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2015 May 13 5 1025-8
Outcomes of Simultaneous Liver Kidney Transplantation in Patients With Hepatocellular Carcinoma
Rich N, Tanriover B, Singal AG, Marrero JA Transplantation 2017 1 101 e12-e19
Effect of fragmentation of cancer care on treatment use and survival in hepatocellular carcinoma.
Hester CA, Karbhari N, Rich NE, Augustine M, Mansour JC, Polanco PM, Porembka MR, Wang SC, Zeh HJ, Singal AG, Yopp AC, Cancer 2019 10 125 19 3428-3436
Racial and Sex Disparities in Hepatocellular Carcinoma in the USA.
Ajayi F, Jan J, Singal AG, Rich NE, Current hepatology reports 2020 Dec 19 4 462-469
Harms of hepatocellular carcinoma surveillance.
Petrasek J, Singal AG, Rich NE, Current hepatology reports 2019 Dec 18 4 383-389
Thrombocytosis is associated with worse survival in patients with hepatocellular carcinoma.
Liu PH, Hsu CY, Su CW, Huang YH, Hou MC, Rich NE, Fujiwara N, Hoshida Y, Singal AG, Huo TI, Liver international : official journal of the International Association for the Study of the Liver 2020 10 40 10 2522-2534
The Mortality and Overall Survival Trends of Primary Liver Cancer in the United States.
Lee YT, Wang JJ, Luu M, Noureddin M, Kosari K, Agopian VG, Rich NE, Lu SC, Tseng HR, Nissen NN, Singal AG, Yang JD, Journal of the National Cancer Institute 2021 May
Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients with Hepatocellular Carcinoma.
Rich NE, Yang JD, Perumalswami PV, Alkhouri N, Jackson W, Parikh ND, Mehta N, Salgia R, Duarte-Rojo A, Kulik L, Rakoski M, Said A, Oloruntoba O, Ioannou GN, Hoteit MA, Moon AM, Rangnekar AS, Eswaran SL, Zheng E, Jou JH, Hanje J, Pillai A, Hernaez R, Wong R, Scaglione S, Samant H, Kapuria D, Chandna S, Rosenblatt R, Ajmera V, Frenette C, Satapathy SK, Mantry P, Jalal P, John BV, Fix OK, Leise M, Lindenmeyer CC, Flores A, Patel N, Jiang ZG, Latt N, Dhanasekaran R, Odewole M, Kagan S, Marrero JA, Singal AG, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2019 Jul
Hepatocellular Carcinoma and Liver Transplantation: Changing Patterns and Practices.
Rich NE, Parikh ND, Singal AG Current treatment options in gastroenterology 2017 Jun 15 2 296-304
Racial and ethnic disparities in non-alcoholic fatty liver disease in the USA.
Rich NE, Noureddin M, Kanwal F, Singal AG, The lancet. Gastroenterology & hepatology 2021 06 6 6 422-424
Hepatocellular carcinoma tumour markers: current role and expectations.
Rich N, Singal AG Best practice & research. Clinical gastroenterology 2014 Oct 28 5 843-53
CON ("The window is closed"): In patients with cirrhosis with ascites, the clinical risks of nonselective beta-blocker outweigh the benefits and should NOT be prescribed.
Aday AW, Rich NE, Mufti AR, Tujios SR, Clinical liver disease 2018 May 11 5 123-127
Direct-Acting Antiviral Therapy not Associated with Recurrence of Hepatocellular Carcinoma in a Multicenter North American Cohort Study.
Singal AG, Rich NE, Mehta N, Branch A, Pillai A, Hoteit M, Volk M, Odewole M, Scaglione S, Guy J, Said A, Feld JJ, John BV, Frenette C, Mantry P, Rangnekar AS, Oloruntoba O, Leise M, Jou JH, Bhamidimarri KR, Kulik L, Tran T, Samant H, Dhanasekaran R, Duarte-Rojo A, Salgia R, Eswaran S, Jalal P, Flores A, Satapathy SK, Wong R, Huang A, Misra S, Schwartz M, Mitrani R, Nakka S, Noureddine W, Ho C, Konjeti VR, Dao A, Nelson K, Delarosa K, Rahim U, Mavuram M, Xie JJ, Murphy CC, Parikh ND Gastroenterology 2019 Jan
Diagnostic and Therapeutic Delays in Patients With Hepatocellular Carcinoma.
Rao A, Rich NE, Marrero JA, Yopp AC, Singal AG, Journal of the National Comprehensive Cancer Network : JNCCN 2021 May 1-14
Use of Hepatocellular Carcinoma Surveillance in Patients With Cirrhosis: A Systematic Review and Meta-Analysis.
Wolf E, Rich NE, Marrero JA, Parikh ND, Singal AG, Hepatology (Baltimore, Md.) 2021 Feb 73 2 713-725
Editorial: liver test abnormalities in oncology patients in the age of the checkpoint inhibitors.
Rich NE, Lee WM, Alimentary pharmacology & therapeutics 2019 10 50 7 831-832
Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma: A Potential New Challenge for Hepatocellular Carcinoma Surveillance.
Rich N, Singal AG Gastroenterology 2016 Dec 151 6 1246-1248
Overdiagnosis: An Understudied Issue in Hepatocellular Carcinoma Surveillance.
Rich NE, Parikh ND, Singal AG Seminars in liver disease 2017 11 37 4 296-304
- Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis.
Results: 2 Locations
Liver Cancer Clinicat Cancer Care Outpatient Building 6202 Harry Hines Blvd., 9th Floor
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University Hospital Kidney and Liver Transplant Clinicat Professional Office Building 2 5939 Harry Hines Blvd., 7th Floor, Suite 700
Dallas, Texas 75390 214-645-1919 Directions to University Hospital Kidney and Liver Transplant Clinic Parking Info for University Hospital Kidney and Liver Transplant Clinic