Panagiotis Mastorakos, M.D., Ph.D.

Panagiotis Mastorakos, M.D., Ph.D.

  • Neurological Surgery
  • Cerebrovascular Disease
  • Aneurysms

Biography

Panagiotis Mastorakos, M.D., Ph.D., is an Assistant Professor in the Department of Neurological Surgery at UT Southwestern Medical Center. He specializes in the treatment of cerebrovascular diseases, aneurysms, vascular malformations, subarachnoid hemorrhage, and ischemic and hemorrhagic stroke.

Dr. Mastorakos earned his medical degree and a doctoral degree in neurosurgery at the University of Athens School of Health Sciences in Greece. He completed a residency in neurosurgery at the National Institutes of Health and the University of Virginia, during which he also gained advanced training through a fellowship in endovascular neurosurgery. Subsequently, he completed an additional fellowship in cerebrovascular and endovascular neurosurgery at Thomas Jefferson University Hospital.

He joined the faculty at UT Southwestern in 2023.

Parallel to his clinical practice, Dr. Mastorakos’ research interests focus on understanding the role of the immune system in damage and repair following stroke and subarachnoid hemorrhage. He aims to further the connection between bench research and clinical practice to improve our basic understanding of these diseases and improve patient care. In 2023, Dr. Mastorakos received the Disease-Oriented Clinical Scholars Program Award from UT Southwestern to pursue these goals.

A member of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, Dr. Mastorakos also serves as an ad hoc reviewer for numerous peer-reviewed journals.

Dr. Mastorakos has presented his research to audiences across the globe and has published scores of articles in peer-reviewed journals related to the treatment of cerebrovascular diseases, general neurosurgery, neuroimmunology, and nanomedicine. He also has contributed to books related to management of common neurosurgical diseases.

Education & Training
  • Fellowship - University of Virginia (2021-2022), Neurological Surgery
  • Medical School - University of Athens School of Health Sciences, Greece (2006-2012)
  • Fellowship - National Institute of Health (2015-2022), Neurological Surgery
  • Residency - National Institute of Health (2015-2022)
  • Other Post Graduate Training - University of Athens School of Health Sciences, Greece (2013-2017)
  • Fellowship - Thomas Jefferson University (2022-2023), Cerebrovascular Neurosurgery
Professional Associations & Affiliations
  • American Association of Neurological Surgeons
  • Congress of Neurological Surgeons
Honors & Awards
  • Disease-Oriented Clinical Scholars (DOCS) Program Award 2023, UT Southwestern
  • Excellence in Research Award 2022, Department of Neurosurgery, University of Virginia
  • Jane-Nugent Basic Science Presentation Award 2022, Neurosurgical Society of the Virginias
  • Donald O. Quest, MD, FAANS(L) Basic Science Award 2021, American Association of Neurological Surgeons Young Neurosurgeons Research Forum
  • Jane-Nugent Basic Science Presentation Award 2021, Neurosurgical Society of the Virginias
  • Clinical Research Excellence Award 2021, National Institute of Neurological Disorders and Stroke
  • Directors Award 2021, National Institute of Neurological Disorders and Stroke
  • Fellows Award for Research Excellence 2021, National Institutes of Health
  • Jane-Nugent Basic Science Presentation Award 2019, Neurosurgical Society of the Virginias
  • John A. Jane, Sr., Highest Board Score Award 2019, University of Virginia
  • Immunology Interest Group Award 2018, Neuroimmunology Session, National Institutes of Health
  • John A. Jane, Sr., Neuroanatomy Award 2017, University of Virginia
  • Award for Research Excellence 2014, Center for Nanomedicine, Johns Hopkins University
  • Scholarship for support of research fellowship 2014, Empeirikeion Foundation
Books & Publications
Research
  • Immune response to acute intracranial pressure fluctuations
  • Innate immune drivers of secondary injury following aneurysmal subarachnoid hemorrhage
  • Development of therapeutics for intraarterial immunomodulation for chronic subdural hemorrhage

Clinical Focus

  • Cerebrovascular Disease
  • Aneurysms
  • Vascular Malformations
  • Subarachnoid Hemorrhage
  • Ischemic and Hemorrhagic Stroke

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