- American Heart Association
- American Society of Echocardiography
- Texas Medical Association
Sadia Malik, M.D.
- Pediatrics - Cardiology
- Pediatric cardiovascular genetics
Biography
Sadia Malik, M.D., M.P.H., is a Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in pediatric cardiovascular genetics.
Dr. Malik earned her medical degree at the Aga Khan University in Pakistan. She completed a residency in pediatrics at the UT Health Science Center at Houston and gained advanced training through a fellowship in pediatric cardiology at UT Southwestern. In addition, she holds a master’s degree in public health from the UT Health Houston School of Public Health.
Board certified in pediatrics and pediatric cardiology, she joined the UT Southwestern faculty in 2015.
Dr. Malik is the Director of the Pediatric Cardiovascular Genetics Clinic and the Program Director for the Pediatric Cardiology Fellowship at UT Southwestern.
Also engaged in service at the state and national level, Dr. Malik is a Pediatric Cardiology consultant reviewer for the Texas Department of Health and a consultant reviewer for the Department of Defense and the National Institutes of Health. She is a member of the Data Sharing Monitoring Board and a pediatric cardiology consultant reviewer for the National Birth Defects Prevention Study.
A member of the American Heart Association, the American Society of Echocardiography, and the Texas Medical Association, Dr. Malik also serves as an ad hoc reviewer for a variety of journals, including Circulation, the American Journal of Cardiology, and Pediatric and Perinatal Epidemiology.
Dr. Malik has lectured widely and published many peer-reviewed articles and case reports related to her areas of expertise. Her research focus is the genetic causes of congenital heart disease.
In 2020, Dr. Malik was rated Best Pediatric Specialist by D Magazine.
Education & Training
- Other Post Graduate Training - UT Health Science Center at Houston (2002-2002)
- Medical School - AGA Khan University, Pakistan (1988-1993)
- Internship - National Institute of Child Health (1993-1994), Pediatrics
- Fellowship - UT Southwestern/Children's Medical Center (1998-2001), Pediatric Cardiology
- Graduate School - UT Health Science Center at Houston (2002-2002)
- Residency - UT Health Science Center McGovern Medical School (1995-1998), Pediatrics
Professional Associations & Affiliations
Honors & Awards
- D Magazine Best Doctor 2023-2025
- Best Pediatric Specialist 2020, D Magazine
Books & Publications
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Books
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Congenital Cardiovascular Malformations – Stevenson Book of Malformations
Lin A, Ghaffar S, Belmont J (2006)
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Congenital Cardiovascular Malformations – Stevenson Book of Malformations
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Publications
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Accelerating Guideline-Recommended Universal Pediatric Lipid Screening: Launch of the LEAD Pediatric Initiative
Flyer JN, Malik S, Hartz J, Farnell JL, Riley CE, Wiskind R, Baker-Smith C, de Ferranti SD, Rea C, Ware AL, Sperling L, Daniels SR Journal of Pediatrics 2026 Jan 288 -
Interaction of maternal medication use with ambient heat exposure on congenital heart defects in the National Birth Defects Prevention Study
Author Collaboration tN, Ou Y, Papadopoulos EA, Fisher SC, Browne ML, Lin Z, Soim A, Lu Y, Sheridan S, Reefhuis J, Langlois PH, Romitti PA, Bell EM, Feldkamp ML, Malik S, Lin S Environmental Research 2022 Dec 215 -
Association between maternal smoking and survival among infants with trisomy 21
Ludorf KL, Benjamin RH, Malik S, Langlois PH, Canfield MA, Agopian AJ Birth Defects Research 2022 Apr 114 249-258 -
Maternal Smoking and Congenital Heart Defects, National Birth Defects Prevention Study, 1997-2011
Author Collaboration NB, Bolin EH, Gokun Y, Romitti PA, Tinker SC, Summers AD, Roberson PK, Hobbs CA, Malik S, Botto LD, Nembhard WN Journal of Pediatrics 2022 Jan 240 79-86.e1 -
Maternal Hypertension-Related Genotypes and Congenital Heart Defects
Lei Y, Ludorf KL, Yu X, Benjamin RH, Gu X, Lin Y, Finnell RH, Mitchell LE, Musfee FI, Malik S, Canfield MA, Morrison AC, Hobbs CA, Van Zutphen AR, Fisher S, Agopian AJ American Journal of Hypertension 2021 Jan 34 82-91 -
Homozygous NEK8 Mutations in Siblings with Neonatal Cholestasis Progressing to End-stage Liver, Renal, and Cardiac Disease
Hassan S, Wolf MT, Umaña LA, Malik S, Uddin N, Andersen J, Aqul A Journal of pediatric gastroenterology and nutrition 2020 Jan 70 E19-E22 -
Two-dimensional systolic speckle tracking echocardiography provides a noninvasive aid in the identification of acute pediatric heart transplant rejection
Engelhardt K, Das B, Sorensen M, Malik S, Zellers T, Lemler M Echocardiography 2019 Oct 36 1876-1883 -
Maternal ambient heat exposure during early pregnancy in summer and spring and congenital heart defects – A large US population-based, case-control study
Author Collaboration tN, Lin S, Lin Z, Ou Y, Soim A, Shrestha S, Lu Y, Sheridan S, Luben TJ, Fitzgerald E, Bell E, Shaw GM, Reefhuis J, Langlois PH, Romitti P, Feldkamp ML, Malik S, Pantea C, Nayak S, Hwang SA, Browne M Environment international 2018 Sep 118 211-221 -
Rationalising the use of cardiac catheterisation before Glenn completion
James L, Tandon A, Nugent A, Malik S, Ramaciotti C, Greil G, Zabala L, Forbess J, Hussain T Cardiology in the Young 2018 May 28 719-724 -
Estimated maternal pesticide exposure from drinkingwater and heart defects in offspring
Author Collaboration NB, Kim J, Swartz MD, Langlois PH, Romitti PA, Weyer P, Mitchell LE, Luben TJ, Ramakrishnan A, Malik S, Lupo PJ, Feldkamp ML, Meyer RE, Winston JJ, Reefhuis J, Blossom SJ, Bell E, Agopian AJ International journal of environmental research and public health 2017 Aug 14 -
Genetic variation affects congenital heart defect susceptibility in offspring exposed to maternal tobacco use
Author Collaboration NB, Tang X, Hobbs CA, Cleves MA, Erickson SW, Macleod SL, Malik S Birth Defects Research Part A - Clinical and Molecular Teratology 2015 Oct 103 834-842 -
Maternal occupational pesticide exposure and risk of congenital heart defects in the national birth defects prevention study
Author Collaboration NB, Rocheleau CM, Bertke SJ, Lawson CC, Romitti PA, Sanderson WT, Malik S, Lupo PJ, Desrosiers TA, Bell E, Druschel C, Correa A, Reefhuis J Birth Defects Research Part A - Clinical and Molecular Teratology 2015 Oct 103 823-833 -
Comparison of in-hospital and longer-term outcomes of hybrid and Norwood stage 1 palliation of hypoplastic left heart syndrome
Malik S, Bird TM, Jaquiss RD, Morrow WR, Robbins JM Journal of Thoracic and Cardiovascular Surgery 2015 Sep 150 474-480.e2 -
Association of Antegrade Pulmonary Artery Diastolic Velocity with Spontaneous Closure of the Patent Ductus Arteriosus in Extremely Low-Birth-Weight Infants
Weiss DM, Kaiser JR, Swearingen C, Malik S, Sachdeva R American Journal of Perinatology 2015 Jun 32 1217-1224 -
Alternative Repair Strategies for Ductal-Dependent Tetralogy of Fallot and Short-Term Postoperative Outcomes, A Multicenter Analysis
Steiner MB, Tang X, Gossett JM, Beam BW, Malik S, Prodhan P, Angtuaco MJ Pediatric Cardiology 2015 Jan 36 177-189 -
Maternal occupational exposure to polycyclic aromatic hydrocarbons and small for gestational age offspring
Langlois PH, Hoyt AT, Desrosiers TA, Lupo PJ, Lawson CC, Waters MA, Rocheleau CM, Shaw GM, Romitti PA, Gilboa SM, Malik S Occupational and Environmental Medicine 2014 Aug 71 529-535 -
Timing of complete repair of non-ductal-dependent tetralogy of Fallot and short-term postoperative outcomes, a multicenter analysis
Steiner MB, Tang X, Gossett JM, Malik S, Prodhan P Journal of Thoracic and Cardiovascular Surgery 2014 Apr 147 1299-1305 -
Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways
Hobbs CA, Cleves MA, Macleod SL, Erickson SW, Tang X, Li J, Li M, Nick T, Malik S Birth Defects Research Part A - Clinical and Molecular Teratology 2014 Feb 100 116-126 -
Prenatal exposure to nitrosatable drugs, vitamin C, and risk of selected birth defects
Shinde MU, Vuong AM, Brender JD, Werler MM, Kelley KE, Huber JC, Sharkey JR, Zheng Q, Suarez L, Langlois PH, Canfield MA, Romitti PA, Malik S Birth Defects Research Part A - Clinical and Molecular Teratology 2013 Aug 97 515-531 -
Maternal occupational exposure to polycyclic aromatic hydrocarbons and congenital heart defects among offspring in the national birth defects prevention study
Lupo PJ, Symanski E, Langlois PH, Lawson CC, Malik S, Gilboa SM, Lee LJ, Agopian AJ, Desrosiers TA, Waters MA, Romitti PA, Correa A, Shaw GM, Mitchell LE Birth Defects Research Part A - Clinical and Molecular Teratology 2012 Nov 94 875-881 -
Early detection of cardiac dysfunction by strain and strain rate imaging in children and young adults with Marfan syndrome
Angtuaco MJ, Vyas HV, Malik S, Holleman BN, Gossett JM, Sachdeva R Journal of Ultrasound in Medicine 2012 Oct 31 1609-1616 -
Nitrosatable drug exposure during the first trimester of pregnancy and selected congenital malformations
Brender JD, Werler MM, Shinde MU, Vuong AM, Kelley KE, Huber JC, Sharkey JR, Griesenbeck JS, Romitti PA, Malik S, Suarez L, Langlois PH, Canfield MA Birth Defects Research Part A - Clinical and Molecular Teratology 2012 Sep 94 701-713 -
Noninvasive estimation of diastolic pulmonary artery pressure by doppler analysis of tricuspid regurgitation velocity in pediatric patients
Angtuaco MJ, Vyas HV, Malik S, Seib PM, Morrow WR, Sachdeva R Congenital Heart Disease 2012 Mar 7 131-138 -
Doppler tissue imaging and catheter-derived measures are not independent predictors of rejection in pediatric heart transplant recipients
Sachdeva R, Malik S, Seib PM, Frazier EA, Cleves MA International Journal of Cardiovascular Imaging 2011 Oct 27 947-954 -
Risk factors for prosthesis failure in pulmonary valve replacement
Zubairi R, Malik S, Jaquiss RD, Imamura M, Gossett J, Morrow WR Annals of Thoracic Surgery 2011 Feb 91 561-565 -
Maternal smoking and congenital heart defects
Malik S, Cleves MA, Honein MA, Romitti PA, Botto LD, Yang S, Hobbs CA Obstetrical and Gynecological Survey 2008 Aug 63 497-498 -
Maternal urinary tract infections and selected cardiovascular malformations
Cleves MA, Malik S, Yang S, Carter TC, Hobbs CA Birth Defects Research Part A - Clinical and Molecular Teratology 2008 Jun 82 464-473 -
Tricuspid Annular and Septal Doppler Tissue Velocities Are Reduced in Pediatric Heart Transplant Recipients Without Acute Rejection
Sachdeva R, Malik S, Bornemeier RA, Frazier EA, Cleves MA Journal of the American Society of Echocardiography 2008 Jun 21 720-724 -
Maternal smoking and congenital heart defects
Malik S, Cleves MA, Honein MA, Romitti PA, Botto LD, Yang S, Hobbs CA Pediatrics 2008 Apr 121 e810-e816 -
Seeking causes: Classifying and evaluating congenital heart defects in etiologic studies
Botto LD, Lin AE, Riehle-Colarusso T, Malik S, Correa A Birth Defects Research Part A - Clinical and Molecular Teratology 2007 Oct 79 714-727 -
Association between congenital heart defects and small for gestational age
Malik S, Cleves MA, Zhao W, Correa A, Hobbs CA Pediatrics 2007 Apr 119 e976-e982 -
Maternal homocysteine and congenital heart defects [1]
Hobbs CA, Malik S, Zhao W, James SJ, Melnyk S, Cleves MA Journal of the American College of Cardiology 2006 Feb 47 683-685 -
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydroflate reductase gene: Evaluating gene-environment interactions
Hobbs CA, James SJ, Jernigan S, Melnyk S, Lu Y, Malik S, Cleves MA American journal of obstetrics and gynecology 2006 Jan 194 218-224 -
NKX2.5 and congenital heart defects: A population-based study [1]
Hobbs CA, Cleves MA, Keith C, Ghaffar S, James SJ American Journal of Medical Genetics 2005 Apr 134 A 223-225 -
Trisomy 21 and congenital heart disease: Effect of timing of initial echocardiogram
Malik S, Lemler MS, Fixler DE, Ramaciotti C Clinical Pediatrics 2005 Jan 44 39-42 -
Effect of proximity to hazardous waste sites on the development of congenital heart disease
Malik S, Schecter A, Caughy M, Fixler DE Archives of Environmental Health 2004 Apr 59 177-181 -
Management of Hypoplastic Left Heart Syndrome [10] (multiple letters)
Tilford JM, Cleves MA, Ghaffar S, Chang RK, Chen A, Klitzner T Pediatrics 2004 Feb 113 431-432 -
Management of Hypoplastic Left Heart Syndrome [1] (multiple letters)
Tilford JM, Cleves MA, Ghaffar S, Chang RK, Chen AY, Klitzner TS Pediatrics 2003 Nov 112 1210-1211 -
First-year survival of infants born with congenital heart defects in Arkansas (1993-1998): A survival analysis using registry data
Cleves MA, Ghaffar S, Zhao W, Mosley BS, Hobbs CA Birth Defects Research Part A - Clinical and Molecular Teratology 2003 Sep 67 662-668 -
Diaphragmatic hernia: An unusual cause of dyspnea in a patient with Marfan syndrome
Yetman AT, Greenberg SB, Ghaffar S Pediatric Cardiology 2003 May 24 307-308 -
Sedation for pediatric echocardiography: Evaluation of preprocedure fasting guidelines
Ghaffar S, Haverland C, Ramaciotti C, Scott WA, Lemler MS Journal of the American Society of Echocardiography 2002 Sep 15 980-983 -
Transient first-degree atrioventricular block following intercostal nerve block for vascular ring repair
Ghaffar S, Scott WA Pediatric Cardiology 2001 22 66-67
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Accelerating Guideline-Recommended Universal Pediatric Lipid Screening: Launch of the LEAD Pediatric Initiative
Research
- Genetic causes of congenital heart disease
Clinical Focus
- Pediatric cardiovascular genetics
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas