Featured Breast Cancer Clinical Trial
A Study of Multiple Immune and Disease Treatment Combinations in Participants With ER+HER2- Breast Cancer That Has Spread:
The purpose of this study is to test the effectiveness (how well the drug works), safety, and tolerability of nivolumab in combination with chemotherapy drug nab-paclitaxel and/or another immunotherapy drugs including, but not limited to, ipilimumab in participants with breast cancer. This clinical trial is targeting multiple mechanisms involved in generating and maintaining antitumor immune response will lead to a tolerable and robust anti-tumor response. This study utilizes an innovative clinical trial design to determine the safety, tolerability, pharmacodynamic activity and efficacy of targeting multiple, distinct combination regimens that modulate several immune and non-immune mechanisms by escalating the number of therapies administered.