- American Society of Blood and Marrow Transplantation

Amir Toor, M.D.
- Internal Medicine - Hematology/Oncology
- Autologous and Allogeneic Stem Cell Transplantation
- Graft-Versus-Host Disease
Biography
Amir Toor, M.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He specializes in autologous and allogeneic stem cell transplantation and cellular immunotherapy for hematological malignancies, graft-versus-host disease, and transplant immunology.
Dr. Toor earned his medical degree at King Edward Medical University in Lahore, Pakistan. He completed a residency in internal medicine at UConn Health and its affiliated hospitals and gained advanced training through a hematology, oncology, and bone marrow transplantation fellowship at the University of Minnesota Medical Center.
Certified by the American Board of Internal Medicine in hematology and internal medicine, he joined the UT Southwestern faculty in 2025. He previously served as medical director of the Stem Cell Transplant and Cellular Therapy Program at the Lehigh Valley Health Network’s Topper Cancer Institute in Allentown, Pennsylvania. Prior to that, he held faculty appointments at Virginia Commonwealth University in Richmond, Virginia, Loyola University Medical Center in Maywood, Illinois, and the University of Arkansas in Little Rock.
Dr. Toor is a member of the American Society of Blood and Marrow Transplantation.
He has delivered numerous presentations and published more than 100 abstracts and more than 90 peer-reviewed academic articles related to his areas of expertise.
Personal Note
When he’s not at work, Dr. Toor enjoys gardening, reading books on physics, and spending time with his family.
Professional Associations & Affiliations
Honors & Awards
- Distinguished Mentor Award 2021, Department of Internal Medicine, Virginia Commonwealth University
- Outstanding Mentor Award 2017, Department of Internal Medicine, Virginia Commonwealth University
- Distinguished Scholarship Award 2016, Department of Internal Medicine, Virginia Commonwealth University
Books & Publications
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Publications
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Understanding Telomere Biology in Hematopoietic Cell Transplantation: A Dynamical Systems Perspective
Amir A. Toor, Morgan Horton, Haniya Khalid, Elizabeth Krieger, Tsung-Po Lai, Stephen R. Spellman, John E. Levine, Wael Saber, Abraham Aviv, Valerie Stewart, Shahinaz M Gadalla Medrxiv 2025 -
Feasibility of intravenous vitamin C supplementation in allogeneic hematopoietic cell transplant recipients.
Simmons GL, Sabo R, Qayyum R, Aziz M, Martin E, Bernard RJ, Sriparna M, McIntire C, Krieger E, Brophy DF, Natarajan R, Iii AF, Roberts CH, Toor A, EJHaem 2024 Oct 5 5 1043-1047 -
SARS-CoV-2 Vaccination in the First Year After Hematopoietic Cell Transplant or Chimeric Antigen Receptor T-Cell Therapy: A Prospective, Multicenter, Observational Study.
Hill JA, Martens MJ, Young JH, Bhavsar K, Kou J, Chen M, Lee LW, Baluch A, Dhodapkar MV, Nakamura R, Peyton K, Howard DS, Ibrahim U, Shahid Z, Armistead P, Westervelt P, McCarty J, McGuirk J, Hamadani M, DeWolf S, Hosszu K, Sharon E, Spahn A, Toor AA, Waldvogel S, Greenberger LM, Auletta JJ, Horowitz MM, Riches ML, Perales MA, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Aug 79 2 542-554 -
Increased donor inhibitory KIR are associated with reduced GVHD and improved survival following HLA-matched unrelated donor HCT in paediatric acute leukaemia.
Krieger E, Qayyum R, Toor A, British journal of haematology 2024 May 204 5 1935-1943 -
Defining and Grading Infections in Clinical Trials Involving Hematopoietic Cell Transplantation: A Report From the BMT CTN Infectious Disease Technical Committee.
Shahid Z, Etra AM, Levine JE, Riches ML, Baluch A, Hill JA, Nakamura R, Toor AA, Ustun C, Young JH, Perales MA, Epstein DJ, Murthy HS, Transplantation and cellular therapy 2024 May 30 5 540.e1-540.e13 -
SARS-CoV-2 vaccination in the first year after hematopoietic cell transplant or chimeric antigen receptor T cell therapy: A prospective, multicenter, observational study (BMT CTN 2101).
Hill JA, Martens MJ, Young JH, Bhavsar K, Kou J, Chen M, Lee LW, Baluch A, Dhodapkar MV, Nakamura R, Peyton K, Howard DS, Ibrahim U, Shahid Z, Armistead P, Westervelt P, McCarty J, McGuirk J, Hamadani M, DeWolf S, Hosszu K, Sharon E, Spahn A, Toor AA, Waldvogel S, Greenberger LM, Auletta JJ, Horowitz MM, Riches ML, Perales MA, medRxiv : the preprint server for health sciences 2024 Jan -
Differential Antibody Response To Polysaccharide Vaccines Following Allogeneic Stem Cell Transplantation; A Dynamical Systems Perspective
Viktoriya Zelikson, Maheen Khan, Morgan Horton, Thuy Ho, Catherine Roberts, Amir Toor 2024 -
Cell-free next-generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study.
Vissichelli NC, Morales MK, Kolipakkam B, Bryson A, Sabo RT, Toor AA, Transplant infectious disease : an official journal of the Transplantation Society 2023 Feb 25 1 e13954 -
High dose valacyclovir for cytomegalovirus prophylaxis following allogeneic hematopoietic cell transplantation.
Hawks KG, Fegley A, Sabo RT, Roberts CH, Toor AA, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2023 Jan 29 1 130-137 -
Allogeneic haematopoietic cell transplants as dynamical systems: influence of early-term immune milieu on long-term T-cell recovery.
Zelikson V, Sabo R, Serrano M, Aqeel Y, Ward S, Al Juhaishi T, Aziz M, Krieger E, Simmons G, Roberts C, Reed J, Buck G, Toor A, Clinical & translational immunology 2023 12 7 e1458 -
Dynamical Systems Modeling of Early-Term Immune Reconstitution with Different Antithymocyte Globulin Administration Schedules in Allogeneic Stem Cell Transplantation.
Zelikson V, Simmons G, Raman N, Krieger E, Rebiero A, Hawks K, Aziz M, Roberts C, Chesney A, Reed J, Gress R, Toor A, Transplantation and cellular therapy 2022 Feb 28 2 85.e1-85.e9 -
Correction: Increased donor inhibitory KIR with known HLA interactions provide protection from relapse following HLA matched unrelated donor HCT for AML.
Krieger E, Qayyum R, Keating A, Toor A, Bone marrow transplantation 2021 Nov 56 11 2871 -
Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience.
Vecchié A, Thomas G, Bressi E, Bonaventura A, Canada JM, Chuquin D, Kadariya D, Piracha U, Endicott D, Markley R, Toor A, Hess M, Abbate A, Cardio-oncology (London, England) 2021 Nov 7 1 40 -
Killer Immunoglobulin-Like Receptor-Ligand Interactions Predict Clinical Outcomes following Unrelated Donor Transplantations.
Krieger E, Sabo R, Moezzi S, Cain C, Roberts C, Kimball P, Chesney A, McCarty J, Keating A, Romee R, Wiedl C, Qayyum R, Toor A, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2020 Apr 26 4 672-682 -
Can Graft vs. Leukemia Effect Be Uncoupled From Graft vs. Host Disease? An Examination of Proportions.
Krieger E, Toor AA, Frontiers in immunology 2020 11 777 -
Managing post allograft relapse of myeloid neoplasms: azacitidine and donor lymphocyte infusions as salvage therapy.
Claiborne J, Bandyopathyay D, Roberts C, Hawks K, Aziz M, Simmons G, Wiedl C, Chung H, Clark W, McCarty J, Toor A, Leukemia & lymphoma 2019 Nov 60 11 2733-2743 -
Reduced plasma ascorbic acid levels in recipients of myeloablative conditioning and hematopoietic cell transplantation.
Rasheed M, Simmons G, Fisher B, Leslie K, Reed J, Roberts C, Natarajan R, Fowler A, Toor A, European journal of haematology 2019 Oct 103 4 329-334 -
T Cell Repertoire Evolution after Allogeneic Bone Marrow Transplantation: An Organizational Perspective.
Meier JA, Haque M, Fawaz M, Abdeen H, Coffey D, Towlerton A, Abdeen A, Toor A, Warren E, Reed J, Kanakry CG, Keating A, Luznik L, Toor AA, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2019 May 25 5 868-882 -
A dynamical systems perspective on chimeric antigen receptor T-cell dosing.
Toor AA, Chesney A, Zweit J, Reed J, Hashmi SK, Bone marrow transplantation 2019 Mar 54 3 485-489 -
Maintenance azacitidine after myeloablative allogeneic hematopoietic cell transplantation for myeloid malignancies.
Maples KT, Sabo RT, McCarty JM, Toor AA, Hawks KG, Leukemia & lymphoma 2018 Dec 59 12 2836-2841 -
The influence of lymphoid reconstitution kinetics on clinical outcomes in allogeneic stem cell transplantation.
Kobulnicky DJ, Sabo RT, Sharma S, Shubar Ali AS, Kobulnicky KM, Roberts CH, Clark WB, Chung HM, McCarty JM, Toor AA, Leukemia & lymphoma 2018 Dec 59 12 2973-2981 -
Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation.
Salman A, Koparde V, Hall CE, Jameson-Lee M, Roberts C, Serrano M, AbdulRazzaq B, Meier J, Kennedy C, Manjili MH, Spellman SR, Wijesinghe D, Hashmi S, Buck G, Qayyum R, Neale M, Reed J, Toor AA, Frontiers in immunology 2018 9 2284 -
Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity.
Hall CE, Koparde VN, Jameson-Lee M, Elnasseh AG, Scalora AF, Kobulnicky DJ, Serrano MG, Roberts CH, Buck GA, Neale MC, Nixon DE, Toor AA, PloS one 2017 12 8 e0178763 -
Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation.
Koparde V, Abdul Razzaq B, Suntum T, Sabo R, Scalora A, Serrano M, Jameson-Lee M, Hall C, Kobulnicky D, Sheth N, Feltz J, Contaifer D, Wijesinghe D, Reed J, Roberts C, Qayyum R, Buck G, Neale M, Toor A, PloS one 2017 12 12 e0187771 -
Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential in HLA-Matched and -Mismatched Donor-Recipient Pairs.
Abdul Razzaq B, Scalora A, Koparde VN, Meier J, Mahmood M, Salman S, Jameson-Lee M, Serrano MG, Sheth N, Voelkner M, Kobulnicky DJ, Roberts CH, Ferreira-Gonzalez A, Manjili MH, Buck GA, Neale MC, Toor AA, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2016 May 22 5 850-61 -
On the organization of human T-cell receptor loci: log-periodic distribution of T-cell receptor gene segments.
Toor AA, Toor AA, Rahmani M, Manjili MH, Journal of the Royal Society, Interface 2016 Jan 13 114 20150911 -
Dynamical System Modeling of Immune Reconstitution after Allogeneic Stem Cell Transplantation Identifies Patients at Risk for Adverse Outcomes.
Toor AA, Sabo RT, Roberts CH, Moore BL, Salman SR, Scalora AF, Aziz MT, Shubar Ali AS, Hall CE, Meier J, Thorn RM, Wang E, Song S, Miller K, Rizzo K, Clark WB, McCarty JM, Chung HM, Manjili MH, Neale MC, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2015 Jul 21 7 1237-45 -
Whole exome sequencing to estimate alloreactivity potential between donors and recipients in stem cell transplantation.
Sampson JK, Sheth NU, Koparde VN, Scalora AF, Serrano MG, Lee V, Roberts CH, Jameson-Lee M, Ferreira-Gonzalez A, Manjili MH, Buck GA, Neale MC, Toor AA, British journal of haematology 2014 Aug 166 4 566-70 -
Stem cell transplantation as a dynamical system: are clinical outcomes deterministic?
Toor AA, Kobulnicky JD, Salman S, Roberts CH, Jameson-Lee M, Meier J, Scalora A, Sheth N, Koparde V, Serrano M, Buck GA, Clark WB, McCarty JM, Chung HM, Manjili MH, Sabo RT, Neale MC, Frontiers in immunology 2014 5 613 -
Fractal organization of the human T cell repertoire in health and after stem cell transplantation.
Meier J, Roberts C, Avent K, Hazlett A, Berrie J, Payne K, Hamm D, Desmarais C, Sanders C, Hogan KT, Archer KJ, Manjili MH, Toor AA, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 Mar 19 3 366-77 -
Anti-thymocyte globulin for conditioning in matched unrelated donor hematopoietic cell transplantation provides comparable outcomes to matched related donor recipients.
Portier DA, Sabo RT, Roberts CH, Fletcher DS, Meier J, Clark WB, Neale MC, Manjili MH, McCarty JM, Chung HM, Toor AA, Bone marrow transplantation 2012 Dec 47 12 1513-9 -
Epigenetic induction of adaptive immune response in multiple myeloma: sequential azacitidine and lenalidomide generate cancer testis antigen-specific cellular immunity.
Toor AA, Payne KK, Chung HM, Sabo RT, Hazlett AF, Kmieciak M, Sanford K, Williams DC, Clark WB, Roberts CH, McCarty JM, Manjili MH, British journal of haematology 2012 Sep 158 6 700-11 -
Favorable outcomes in patients with high donor-derived T cell count after in vivo T cell-depleted reduced-intensity allogeneic stem cell transplantation.
Toor AA, Sabo RT, Chung HM, Roberts C, Manjili RH, Song S, Williams DC, Edmiston W, Gatesman ML, Edwards RW, Ferreira-Gonzalez A, Clark WB, Neale MC, McCarty JM, Manjili MH, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012 May 18 5 794-804 -
Distinct oligoclonal T cells are associated with graft versus host disease after stem-cell transplantation.
Berrie JL, Kmieciak M, Sabo RT, Roberts CH, Idowu MO, Mallory K, Chung HM, McCarty JM, Borrelli CA, Detwiler MM, Kazim AL, Toor AA, Manjili MH, Transplantation 2012 May 93 9 949-57 -
Impaired NHEJ function in multiple myeloma.
Yang C, Betti C, Singh S, Toor A, Vaughan A, Mutation research 2009 Jan 660 1-2 66-73 -
Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT.
Toor A, Rodriguez T, Bauml M, Mathews H, Shanti S, Senitzer D, Kini A, Norton J, Parthasarathy M, Mohideen N, Petrowsky C, Bonilla B, Smith S, Stiff P, Bone marrow transplantation 2008 Dec 42 11 723-31 -
Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections.
Mullane K, Toor AA, Kalnicky C, Rodriguez T, Klein J, Stiff P, Transplant infectious disease : an official journal of the Transplantation Society 2007 Jun 9 2 89-96 -
Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity.
Toor AA, Stiff PJ, Nickoloff BJ, Rodriguez T, Klein JL, Gordon KB, The Journal of dermatological treatment 2007 18 1 13-8 -
Autologous hematopoietic stem cell transplants that utilize total body irradiation can safely be carried out entirely on an outpatient basis.
Stiff P, Mumby P, Miler L, Rodriguez T, Parthswarthy M, Kiley K, Porter N, Batiste R, Wojtowitz S, Lichtenstein S, Fox-Geiman M, Toor A, Bone marrow transplantation 2006 Dec 38 11 757-64 -
Second allografts for relapsed hematologic malignancies: feasibility of using a different donor.
Duus JE, Stiff PJ, Choi J, Parthasarathy M, Rodriguez T, Toor AA, Bone marrow transplantation 2005 Feb 35 3 261-4 -
Favourable results with a single autologous stem cell transplant following conditioning with busulphan and cyclophosphamide in patients with multiple myeloma.
Toor AA, Ayers J, Strupeck J, Parthasarathy M, Creech S, Rodriguez T, Stiff PJ, British journal of haematology 2004 Mar 124 6 769-76 -
BEAM allogeneic transplantation for patients with Hodgkin's disease who relapse after autologous transplantation is safe and effective.
Cooney JP, Stiff PJ, Toor AA, Parthasarathy M, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003 Mar 9 3 177-82 -
Predicting long-term (> or = 5 years) event-free survival in multiple myeloma patients following planned tandem autotransplants.
Tricot G, Spencer T, Sawyer J, Spoon D, Desikan R, Fassas A, Badros A, Zangari M, Munshi N, Anaissie E, Toor A, Barlogie B, British journal of haematology 2002 Jan 116 1 211-7 -
Infections during mobilizing chemotherapy and following autologous stem cell transplantation.
Toor AA, van Burik JA, Weisdorf DJ, Bone marrow transplantation 2001 Dec 28 12 1129-34 -
High response rate in refractory and poor-risk multiple myeloma after allotransplantation using a nonmyeloablative conditioning regimen and donor lymphocyte infusions.
Badros A, Barlogie B, Morris C, Desikan R, Martin SR, Munshi N, Zangari M, Mehta J, Toor A, Cottler-Fox M, Fassas A, Anaissie E, Schichman S, Tricot G, Blood 2001 May 97 9 2574-9 -
T-cell factor-1 expression during human natural killer cell development and in circulating CD56(+) bright natural killer cells.
Toor AA, Lund TC, Miller JS, Experimental hematology 2001 Apr 29 4 499-506 -
Bleeding risk and platelet transfusion refractoriness in patients with acute myelogenous leukemia who undergo autologous stem cell transplantation.
Toor AA, Choo SY, Little JA, Bone marrow transplantation 2000 Aug 26 3 315-20
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Understanding Telomere Biology in Hematopoietic Cell Transplantation: A Dynamical Systems Perspective
Research
- Clinical trials for optimizing immune recovery following donor stem cell transplant and preventing cancer relapse
- Mathematical modeling of immune system recovery following stem cell transplantation
- Biology of blood cancers
Clinical Focus
- Autologous and Allogeneic Stem Cell Transplantation
- Graft-Versus-Host Disease
- Transplant Immunology