Andrew Koh, M.D., is an Associate Professor in the Department of Pediatrics and the Department of Microbiology at UT Southwestern Medical Center. A member of the Harold C. Simmons Comprehensive Cancer Center, he specializes in pediatric hematology-oncology; cellular therapy, including stem cell transplantation, CAR T-cell therapy and gene therapy; and cancer immunotherapy.

Dr. Koh earned his medical degree at Harvard Medical School. He completed his residency in pediatric medicine at Boston Children’s Hospital, where he served as Chief Resident. He then completed a dual fellowship in hematology-oncology and infectious diseases at Boston Children’s Hospital and the Dana-Farber Cancer Institute.

He is certified by the American Board of Pediatrics in pediatric hematology and oncology.

After serving as an attending physician on both the hematopoietic stem cell transplantation service and immunocompromised infectious diseases service for five years, Dr. Koh left Harvard to become Director of Pediatric Hematopoietic Stem Cell Transplantation at UT Southwestern in 2009.

He is currently the Director of the Pediatric Cellular and ImmunoTherapeutics Program at Children’s Health and Associate Division Chief of Basic Science and Innovation for the Division of Pediatric Hematology and Oncology at UTSW.

The Koh Lab focuses on understanding how the gut microbiome influences host immune responses in cancer and stem cell transplant patients, with a focus on bacterial and fungal infections originating from the gut, autoimmune complications, and anti-tumor immune responses in the context of cancer immunotherapy. These research efforts are funded by the National Institutes of Health (NIH), industry, and foundations.

The lab’s recent work has focused on developing novel gut microbiome-derived therapeutics for enhancing cancer immunotherapy efficacy. These efforts have resulted in the filing of two patents, the acquisition of NIH and American Cancer Society funding, and the co-founding of a startup company, Aumenta Biosciences.

Dr. Koh serves on the NIH Interspecies Microbial Interactions and Infections study section and the Cancer Prevention and Research Institute of Texas Advisory Committee on Childhood Cancers.

Personal Note

When he’s not at work, Dr. Koh enjoys writing and recording music. His main instruments are vocals and guitar, but he also plays keyboards and bass guitar.

Education & Training
  • Medical School - Harvard Medical School (1990-1996)
  • Residency - Children's Hospital of Boston - Pediatric Program (1996-1999), Pediatric Medicine
  • Residency - Children's Hospital of Boston - Pediatric Program (1999-2000), Pediatric Medicine
  • Fellowship - Children's Hospital Boston - Hematology/Oncology (2001-2004), Pediatric Hematology/oncology
  • Fellowship - Children's Hospital Boston - Infectious Disease (2000-2004), Pediatric Infectious Diseases
Professional Associations & Affiliations
  • American Society of Hematology
  • American Society for Microbiology
  • Children’s Oncology Group
  • Pediatric Transplantation and Cellular Therapy Consortium
  • Society for Pediatric Research
Honors & Awards
  • BrightEdge Entrepreneurs Program 2024, American Cancer Society
  • Selected Member, Texas Medical Center Accelerator for Cancer Therapeutics 2021, Texas Medical Center, Cancer Prevention and Research Institute of Texas (CPRIT)
  • Rhodes Scholarship 1988-1990, University of Oxford
Books & Publications
  • Antibiotic resistance
  • Cancer immunotherapy
  • Fungal pathogenesis
  • Gut microbiome
  • Gut microbiota (bacterial-fungal interactions)
  • Host immune anti-tumor response
  • Host-pathogen interactions
  • Intestinal graft-versus-host disease

Clinical Focus

  • Cellular Therapy
  • Cancer Immunotherapy
  • Stem Cell Transplantation
  • CAR T-Cell Therapy
  • Gene Therapy

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