- Fellowship - Yale University School of Medicine (1995-1998), Pediatric Infectious Diseases
- Chief Resident - Yale-New Haven Hospital (1994-1995), Pediatrics
- Residency - Yale-New Haven Hospital (1991-1994), Pediatrics
- Medical School - SUNY Health Science Center at Brooklyn College of Medicine (1983-1991)
Jeffrey Kahn, M.D., Ph.D.
Chief, Division of Pediatric Infectious Disease
- Sarah M. and Charles E. Seay Chair in Pediatric Infectious Diseases
- Pediatrics - Infectious Disease
- Infectious Disease
Jeffrey S. Kahn, M.D., Ph.D. received his Bachelor of Science degree in Microbiology and Immunology from McGill University. He received his M.D. and a Ph.D. in Microbiology and Immunology from the State University of New York Health Science Center at Brooklyn. Dr. Kahn completed his internship, residency and chief residency in Pediatrics at Yale University and the Children’s Hospital at Yale-New Haven Hospital. Dr. Kahn stayed at Yale University to complete training in Pediatric Infectious Diseases. Thereafter, he joined the faculty at Yale University in the Department of Pediatrics in the Division of Infectious Diseases. He joined the faculty of UT Southwestern Medical Center in 2009.
Dr. Kahn’s research efforts have been focused on human respiratory viruses, including respiratory syncytial virus (RSV) and new emerging human viruses. His laboratory was the first or among the first laboratories in the United States to describe the epidemiology and clinical manifestations of several newly identified viruses including human metapneumovirus, coronaviruses NL63 and HKU1, human bocavirus and polyomavirus WUV. His laboratory has described the molecular epidemiology of RSV and has characterized the glycoprotein sequences, completed phylogenetic analyses and defined the biological properties (e.g. induction of cytokines and chemokines) and induced gene expression profiles (using RNA-SEQ) of many of these RSV strains in primary human cells. Dr. Kahn’s current research efforts are focuses on mapping RSV phenotypes in the viral genome.
Dr. Kahn is the Director of the Pediatric Infectious Disease and the Pediatric Infectious Diseases Fellowship Program at UT Southwestern Medical Center and the Director of Infectious Diseases at Children’s Medical Center. Dr. Kahn is the Medical Director of Research at Children’s Medical Center.
- American Academy of Pediatrics
- Society of Pediatric Research (2001)
- American Society of Microbiology (2001)
- American Society of Virology (2002)
- Infectious Diseases Society of America (2010)
- Best Pediatric Specialists, D Magazine, (2014-2018, 2020)
- Pediatric Chair’s Award, Yale University School of Medicine 2005
- Mae Gailani Junior Faculty Award, Yale University School of Medicine 2002
Human Bocavirus: A Newly Discovered Human Parvovirus in Scheld WM, Hooper DC, Hughes JM, eds. Emerging Infections 8.
Kahn JS, Tattersall P. (2008), Washington, DC:ASM Press; 21-38.
- Human Bocavirus: A Newly Discovered Human Parvovirus in Scheld WM, Hooper DC, Hughes JM, eds. Emerging Infections 8.
A 1-year experience with human metapneumovirus in children aged <5 years.
Esper F, Martinello RA, Boucher D, Weibel C, Ferguson D, Landry ML, Kahn JS The Journal of infectious diseases 2004 Apr 189 8 1388-96
Correlation between respiratory syncytial virus genotype and severity of illness.
Martinello RA, Chen MD, Weibel C, Kahn JS The Journal of infectious diseases 2002 Sep 186 6 839-42
The cis-acting DNA sequences required in vivo for bacteriophage Mu helper-mediated transposition and packaging.
Harel J, Duplessis L, Kahn JS, DuBow MS Archives of microbiology 1990 154 1 67-72
Molecular cloning, encoding sequence, and expression of vaccinia virus nucleic acid-dependent nucleoside triphosphatase gene.
Rodriguez JF, Kahn JS, Esteban M Proceedings of the National Academy of Sciences of the United States of America 1986 Dec 83 24 9566-70
WU polyomavirus in patients infected with HIV or hepatitis C virus, Connecticut, USA, 2007.
Miller MA, Weibel C, Ferguson D, Landry ML, Kahn JS Emerging infectious diseases 2009 Jul 15 7 1095-7
Human metapneumovirus and severity of respiratory syncytial virus disease.
Lazar I, Weibel C, Dziura J, Ferguson D, Landry ML, Kahn JS Emerging infectious diseases 2004 Jul 10 7 1318-20
Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific.
Levitz R, Wattier R, Phillips P, Solomon A, Lawler J, Lazar I, Weibel C, Kahn JS Virology journal 2012 9 190
Epidemiology of human metapneumovirus.
Kahn JS Clinical microbiology reviews 2006 Jul 19 3 546-57
Human metapneumovirus, a newly emerging respiratory virus.
Kahn JS The Pediatric infectious disease journal 2003 Oct 22 10 923-4
Respiratory syncytial virus in neutrophils.
Kahn JS The Journal of infectious diseases 2012 Feb 205 4 693; author reply 693-4
Tuning the Gold Nanoparticle Colorimetric Assay by Nanoparticle Size, Concentration, and Size Combinations for Oligonucleotide Detection.
Godakhindi VS, Kang P, Serre M, Revuru NA, Zou JM, Roner MR, Levitz R, Kahn JS, Randrianalisoa J, Qin Z ACS sensors 2017 Oct
Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus.
Levitz R, Gao Y, Dozmorov I, Song R, Wakeland EK, Kahn JS PloS one 2017 12 9 e0184318
Inpatient Bronchiolitis Guideline Implementation and Resource Utilization.
Mittal V, Darnell C, Walsh B, Mehta A, Badawy M, Morse R, Pop R, Tidwell J, Sheehan M, McDermott S, Cannon C, Kahn J Pediatrics 2014 Feb
Seroepidemiology of WU polyomavirus among children exposed perinatally to HIV-1.
Miller MA, Weibel C, Kahn JS, Andiman WA Journal of medical virology 2012 Feb 84 2 188-93
Role of human polyomaviruses in respiratory tract disease in young children.
Wattier RL, Vázquez M, Weibel C, Shapiro ED, Ferguson D, Landry ML, Kahn JS Emerging infectious diseases 2008 Nov 14 11 1766-8
Human metapneumovirus and exacerbations of chronic obstructive pulmonary disease.
Martinello RA, Esper F, Weibel C, Ferguson D, Landry ML, Kahn JS The Journal of infection 2006 Oct 53 4 248-54
Novel mutations in the respiratory syncytial virus G gene identified in viral isolates from a girl with severe combined immune deficiency treated with intravenous immune globulin.
Lazar I, Canaan A, Weibel C, Kahn JS Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006 Nov 37 3 168-73
Human bocavirus infection in young children in the United States: molecular epidemiological profile and clinical characteristics of a newly emerging respiratory virus.
Kesebir D, Vazquez M, Weibel C, Shapiro ED, Ferguson D, Landry ML, Kahn JS The Journal of infectious diseases 2006 Nov 194 9 1276-82
The widening scope of coronaviruses.
Kahn JS Current opinion in pediatrics 2006 Feb 18 1 42-7
History and recent advances in coronavirus discovery.
Kahn JS, McIntosh K The Pediatric infectious disease journal 2005 Nov 24 11 Suppl S223-7, discussion S226
Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children.
Esper F, Weibel C, Ferguson D, Landry ML, Kahn JS The Journal of infectious diseases 2005 Feb 191 4 492-8
Human metapneumovirus infection in the United States: clinical manifestations associated with a newly emerging respiratory infection in children.
Esper F, Boucher D, Weibel C, Martinello RA, Kahn JS Pediatrics 2003 Jun 111 6 Pt 1 1407-10
Human metapneumovirus: a newly emerging respiratory pathogen.
Kahn JS Current opinion in infectious diseases 2003 Jun 16 3 255-8
Conservation of the respiratory syncytial virus SH gene.
Chen MD, Vazquez M, Buonocore L, Kahn JS The Journal of infectious diseases 2000 Oct 182 4 1228-33
Fever without apparent source on clinical examination, lower respiratory infections in children, and enterovirus infections.
McCarthy PL, Klig JE, Kennedy WP, Kahn JS Current opinion in pediatrics 2000 Feb 12 1 77-95
Recombinant vesicular stomatitis virus expressing respiratory syncytial virus (RSV) glycoproteins: RSV fusion protein can mediate infection and cell fusion.
Kahn JS, Schnell MJ, Buonocore L, Rose JK Virology 1999 Feb 254 1 81-91
Fever without apparent source on clinical examination, lower respiratory infections in children, other infectious diseases, and acute gastroenteritis and diarrhea of infancy and early childhood.
McCarthy PL, Klig JE, Kahn JS, Shapiro ED, Baron MA Current opinion in pediatrics 1997 Feb 9 1 105-26
A mutation of the nucleoside triphosphate phosphohydrolase I (NPH-I) gene confers sensitivity of vaccinia virus to interferon.
Díaz-Guerra M, Kahn JS, Esteban M Virology 1993 Nov 197 1 485-91
Identification of the point mutations in two vaccinia virus nucleoside triphosphate phosphohydrolase I temperature-sensitive mutants and role of this DNA-dependent ATPase enzyme in virus gene expression.
Kahn JS, Esteban M Virology 1990 Feb 174 2 459-71
Surveillance of clinical isolates of respiratory syncytial virus for palivizumab (Synagis)-resistant mutants.
DeVincenzo JP, Hall CB, Kimberlin DW, Sánchez PJ, Rodriguez WJ, Jantausch BA, Corey L, Kahn JS, Englund JA, Suzich JA, Palmer-Hill FJ, Branco L, Johnson S, Patel NK, Piazza FM The Journal of infectious diseases 2004 Sep 190 5 975-8
Fever without apparent source on clinical examination, infectious diseases, and lower respiratory infections in children.
McCarthy PL, Kahn JS, Shapiro E, Klig J Current opinion in pediatrics 1998 Feb 10 1 101-16
Rhinoviruses are a major cause of wheezing and hospitalization in children less than 2 years of age.
Piotrowska Z, Vázquez M, Shapiro ED, Weibel C, Ferguson D, Landry ML, Kahn JS The Pediatric infectious disease journal 2009 Jan 28 1 25-9
Seroepidemiology of human bocavirus defined using recombinant virus-like particles.
Kahn JS, Kesebir D, Cotmore SF, D'Abramo A, Cosby C, Weibel C, Tattersall P The Journal of infectious diseases 2008 Jul 198 1 41-50
Newly discovered respiratory viruses: significance and implications.
Kahn JS Current opinion in pharmacology 2007 Oct 7 5 478-83
Coronavirus HKU1 infection in the United States.
Esper F, Weibel C, Ferguson D, Landry ML, Kahn JS Emerging infectious diseases 2006 May 12 5 775-9
Seroepidemiology of human metapneumovirus (hMPV) on the basis of a novel enzyme-linked immunosorbent assay utilizing hMPV fusion protein expressed in recombinant vesicular stomatitis virus.
Leung J, Esper F, Weibel C, Kahn JS Journal of clinical microbiology 2005 Mar 43 3 1213-9
Association between a novel human coronavirus and Kawasaki disease.
Esper F, Shapiro ED, Weibel C, Ferguson D, Landry ML, Kahn JS The Journal of infectious diseases 2005 Feb 191 4 499-502
Replication-competent or attenuated, nonpropagating vesicular stomatitis viruses expressing respiratory syncytial virus (RSV) antigens protect mice against RSV challenge.
Kahn JS, Roberts A, Weibel C, Buonocore L, Rose JK Journal of virology 2001 Nov 75 22 11079-87
Orientation and sequence analysis of right ends and target sites of bacteriophage mu and D108 insertions in the plasmid pSC101.
Szatmari GB, Kahn JS, DuBow MS Gene 1986 41 2-3 315-9
Newly identified respiratory viruses.
Kahn JS The Pediatric infectious disease journal 2007 Aug 26 8 745-6
Respiratory syncytial virus vaccine development.
Kahn JS Current opinion in pediatrics 2000 Jun 12 3 257-62
Seroepidemiology of group I human coronaviruses in children.
Shao X, Guo X, Esper F, Weibel C, Kahn JS Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007 Nov 40 3 207-13
Fever without apparent source on clinical examination, lower respiratory infections in children, and other infectious diseases.
McCarthy PL, Klig JE, Kahn JS Current opinion in pediatrics 1999 Feb 11 1 89-106
RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy.
Alvarez R, Elbashir S, Borland T, Toudjarska I, Hadwiger P, John M, Roehl I, Morskaya SS, Martinello R, Kahn J, Van Ranst M, Tripp RA, DeVincenzo JP, Pandey R, Maier M, Nechev L, Manoharan M, Kotelianski V, Meyers R Antimicrobial agents and chemotherapy 2009 Sep 53 9 3952-62
- A 1-year experience with human metapneumovirus in children aged <5 years.
- Respiratory syncytial virus
- Recombinant negative stand RNA viruses
- Emerging pathogens
- Cellular responses to RSV infection
- Infectious Disease