Kan Ding, M.D.

Peter O'Donnell Jr. Brain Institute

Neurology
Epilepsy & Seizures

Biography

Kan Ding, M.D., is an Associate Professor in the Department of Neurology at UT Southwestern Medical Center, where she is also a practicing neurologist who specializes in treating patients with epilepsy.

Dr. Ding earned her medical degree at Peking Union Medical College in China. She then completed a residency in neurology and a fellowship in epilepsy and clinical neurophysiology at UT Southwestern Medical Center.

In her medical practice and research, Dr. Ding focuses on neurocritical care and post-traumatic epilepsy, which involves finding better ways to treat and rehabilitate patients who’ve developed epilepsy after a traumatic brain injury. She also explores ways to improve ICU EEG monitoring, evaluations for epilepsy surgery, and cerebral functional connectivity.

Meet Dr. Ding

Neurologist Specializing in Epilepsy in Dallas

For Kan Ding, M.D., treating patients with epilepsy is not just about treating the medical condition – it’s about treating the whole patient.

“We need to treat the patient as a whole person,” says Dr. Ding, who received advanced training in epilepsy and clinical neurophysiology at UT Southwestern. “Patients who come to an epileptologist like me for seizure control often also suffer from a lot of other complications. Our goal is to improve their quality of life as a whole.”

While she sees patients with all types and manifestations of epilepsy, Dr. Ding has special expertise evaluating patients with intractable epilepsy – that which cannot be treated with medication – and patients with post-traumatic epilepsy, or epilepsy that develops as a result of traumatic brain injury (TBI).

Dr. Ding is also committed to clinical research and works closely with other specialists at UT Southwestern to study better ways to diagnose, treat, and rehabilitate patients with epilepsy.

Education & Training

Fellowship - UT Southwestern Medical Center (2012-2013), Epilepsy/clinical Neurophysiology
Residency - UT Southwestern Medical Center (2008-2012), Neurology
Medical School - Peking Union Medical College (1989-1997)

Books & Publications

Publications
- Diffusion tensor tractography of traumatic diffuse axonal injury.
  Wang JY, Bakhadirov K, Devous MD, Abdi H, McColl R, Moore C, Marquez de la Plata CD, Ding K, Whittemore A, Babcock E, Rickbeil T, Dobervich J, Kroll D, Dao B, Mohindra N, Madden CJ, Diaz-Arrastia R Archives of neurology 2008 May 65 5 619-26
- Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice.
  Scortegagna M, Ding K, Oktay Y, Gaur A, Thurmond F, Yan LJ, Marck BT, Matsumoto AM, Shelton JM, Richardson JA, Bennett MJ, Garcia JA Nature genetics 2003 Dec 35 4 331-40
- HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner.
  Scortegagna M, Ding K, Zhang Q, Oktay Y, Bennett MJ, Bennett M, Shelton JM, Richardson JA, Moe O, Garcia JA Blood 2005 Apr 105 8 3133-40
- Retinal disease in mice lacking hypoxia-inducible transcription factor-2alpha.
  Ding K, Scortegagna M, Seaman R, Birch DG, Garcia JA Investigative ophthalmology & visual science 2005 Mar 46 3 1010-6
- Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin.
  Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, Garcia JA The Journal of biological chemistry 2007 Apr 282 16 11750-6
- Retrospective case series of the clinical features, management and outcomes of patients with autoimmune epilepsy.
  Dubey D, Samudra N, Gupta P, Agostini M, Ding K, Van Ness PC, Vernino S, Hays R Seizure 2015 Jul 29 143-7
- Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research.
  Lee JW, LaRoche S, Choi H, Rodriguez Ruiz AA, Fertig E, Politsky JM, Herman ST, Loddenkemper T, Sansevere AJ, Korb PJ, Abend NS, Goldstein JL, Sinha SR, Dombrowski KE, Ritzl EK, Westover MB, Gavvala JR, Gerard EE, Schmitt SE, Szaflarski JP, Ding K, Haas KF, Buchsbaum R, Hirsch LJ, Wusthoff CJ, Hopp JL, Hahn CD Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2016 Apr 33 2 133-140
- Diagnostic Yield of 2-Hour EEG Is Similar With 30-Minute EEG in Patients With a Normal 30-Minute EEG.
  Mahuwala Z, Ahmadi S, Bozoky Z, Hays R, Agostini M, Ding K, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2019 Feb
- Assessing recent suicidal ideation and behavior in the adult epilepsy monitoring unit.
  Husari KS, Blackburn KM, Ding K, Roaten K, Hays R, Epilepsy & behavior : E&B 2019 Mar 94 100-103
- Physical activity status and quality of life in patients with epilepsy - Survey from level four epilepsy monitoring units.
  Green R, Abe C, Denney DA, Zhang R, Doyle A, Gadelmola K, Cullum CM, Simon J, Neaves S, Perven G, Dieppa M, Hays R, Agostini M, Ding K, Epilepsy research 2021 Apr 173 106639
- Predictors of Postoperative Seizure Recurrence: A Longitudinal Study of Temporal and Extratemporal Resections.
  Chen H, Modur PN, Barot N, Van Ness PC, Agostini MA, Ding K, Gupta P, Hays R, Mickey B Epilepsy research and treatment 2016 2016 7982494
- Arterial Pressure, Heart Rate, and Cerebral Hemodynamics Across the Adult Life Span.
  Xing CY, Tarumi T, Meijers RL, Turner M, Repshas J, Xiong L, Ding K, Vongpatanasin W, Yuan LJ, Zhang R Hypertension (Dallas, Tex. : 1979) 2017 Feb
- Cardiorespiratory Fitness and White Matter Neuronal Fiber Integrity in Mild Cognitive Impairment.
  Ding K, Tarumi T, Zhu DC, Tseng BY, Thomas BP, Turner M, Repshas J, Kerwin DR, Womack KB, Lu H, Cullum CM, Zhang R Journal of Alzheimer's disease : JAD 2018 61 2 729-739
- Central autonomic network functional connectivity: correlation with baroreflex function and cardiovascular variability in older adults.
  Ding K, Tarumi T, Wang C, Vernino S, Zhang R, Zhu DC, Brain structure & function 2020 Apr
- Math5 determines the competence state of retinal ganglion cell progenitors.
  Yang Z, Ding K, Pan L, Deng M, Gan L Developmental biology 2003 Dec 264 1 240-54
- Impaired cerebral blood flow regulation in chronic traumatic brain injury.
  Ding K, Tarumi T, Tomoto T, Mccolloster M, Le T, Dieppa M, Diaz-Arrastia R, Bell K, Madden C, Cullum CM, Zhang R, Brain research 2020 Sep 1743 146924
- ¹²³I-iofluopane SPECT as An Imaging Biomarker of Presynaptic Dopaminergic System after Moderate to Severe TBI.
  Womack KB, Dubiel R, Callender L, Dunklin C, Dahdah M, Harris TS, Devous M, Juengst S, Bell K, Diaz-Arrastia R, Ding K, Journal of neurotrauma 2020 Mar
- Estimation of Heart Rate Variability Measures Using Apple Watch and Evaluating Their Accuracy: Estimation of Heart Rate Variability Measures Using Apple Watch
  Turki, A., Behbehani, K., Ding, K., Zhang, R., Li, M., Bell, K. 2021 29 June 2021 Pages 565 - 574
- Non-lesional mesial temporal lobe epilepsy requires bilateral invasive evaluation.
  Perven G, Podkorytova I, Ding K, Agostini M, Alick S, Das R, Dave H, Dieppa M, Doyle A, Harvey J, Lega B, Zepeda R, Hays R, Epilepsy & behavior reports 2021 15 100441
- Emergency department visits and readmissions in patients with psychogenic nonepileptic seizures (PNES) at a safety net hospital.
  Ramamurthy S, Steven Brown L, Agostini M, Alick Lindstorm S, Dave H, Dieppa M, Ding K, Doyle A, Hays R, Harvey J, Perven G, Podkorytova I, Zepeda R, Das RR, Epilepsy & behavior : E&B 2021 Aug 122 108225
- Hippocampal and Rostral Anterior Cingulate Blood Flow is Associated with Affective Symptoms in Chronic Traumatic Brain Injury.
  Thomas BP, Tarumi T, Wang C, Zhu DC, Tomoto T, Munro Cullum C, Dieppa M, Diaz-Arrastia R, Bell K, Madden C, Zhang R, Ding K, Brain research 2021 Aug 147631
- A proof-of-concept trial of a community-based aerobic exercise program for individuals with traumatic brain injury.
  Ding K, Tarumi T, Tomoto T, Bell KR, Madden C, Dieppa M, Cullum CM, Zhang S, Zhang R, Brain injury 2021 Jan 1-8
- Emergent Admissions to the Epilepsy Monitoring Unit in the Setting of COVID-19 Pandemic-related, State-mandated Restrictions: Clinical Decision Making and Outcomes.
  Zepeda R, Lee Y, Agostini M, Alick Lindstrom S, Dave H, Dieppa M, Ding K, Doyle A, Harvey J, Hays R, Perven G, Podkorytova I, Das RR, The Neurodiagnostic journal 2021 Jun 61 2 95-103
- Carotid Arterial Compliance and Aerobic Exercise Training in Chronic Traumatic Brain Injury: A Pilot Study.
  Tomoto T, Le T, Tarumi T, Dieppa M, Bell K, Madden C, Zhang R, Ding K, The Journal of head trauma rehabilitation 2021 Sep
- Interictal Epileptiform Discharge Detection in EEG in Different Practice Settings.
  Halford JJ, Westover MB, LaRoche SM, Macken MP, Kutluay E, Edwards JC, Bonilha L, Kalamangalam GP, Ding K, Hopp JL, Arain A, Dawson RA, Martz GU, Wolf BJ, Waters CG, Dean BC Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2018 Jul
- Comparison of psychiatric comorbidities and impact on quality of life in patients with epilepsy or psychogenic nonepileptic spells.
  Abe C, Denney D, Doyle A, Cullum M, Adams J, Perven G, Dave H, Dieppa M, Hays R, Agostini M, Ding K, Epilepsy & behavior : E&B 2019 Nov 102 106649
- HIF-2alpha-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery.
  Dioum EM, Clarke SL, Ding K, Repa JJ, Garcia JA Investigative ophthalmology & visual science 2008 Jun 49 6 2714-20
- A wearable fitness tracking ecosystem for exercise therapy for traumatic brain injury patients
  Turki A., Ding K., Zhang R., Li M., Bell K., Behbehani K. 2020 30 June 2020 Pages 362 - 369
- Subtypes of Post-Traumatic Epilepsy: Clinical, Electrophysiologic, and Imaging Features
  Gupta, P. Ding, K. Sayed, N. Agostini, M. Van Ness, P. Madden, C. Mickey, B. D'Ambrosio, R. Diaz-Arrastia, R. Journal of Neurotrauma 2014 16 31 1439
- An Investigation of Heartrate Sensing Accuracy by Wrist-Worn Fitness Tracking Devices.
  Turki AF, Jani MB, Ding K, Zhang R, Behbehani K, Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2019 Jul 2019 3337-3340
- Cerebral atrophy after traumatic white matter injury: correlation with acute neuroimaging and outcome
  Ding, K. Marquez de la Plata, C. Wang, J. Y. Mumphrey, M. Moore, C. Harper, C. Madden, C. J. McColl, R. Whittemore, A. Devous, M. D. Diaz-Arrastia, R. Journal of Neurotrauma 2008 25 12 1433-40
- Regional atrophy in temporal lobe epilepsy: correlations with cognitive impairment.
  Ding K, Gong Y, Gupta P, Frol A, McColl R, Agostini M, Modur P, Van Ness P, Diaz-Arrastia R. Journal of neurological disorders & stroke 2014 3 2 1053
- Requirement for math5 in the development of retinal ganglion cells.
  Wang SW, Kim BS, Ding K, Wang H, Sun D, Johnson RL, Klein WH, Gan L, Genes & development 2001 Jan 15 1 24-9
- Diffusion tensor tractography of traumatic diffuse axonal injury
  Wang, J. Y. Bakhadirov, K. Devous, M. D., Sr. Abdi, H. McColl, R. Moore, C. Marquez de la Plata, C. D. Ding, K. Whittemore, A. Babcock, E. Rickbeil, T. Dobervich, J. Kroll, D. Dao, B. Mohindra, N. Madden, C. J. Diaz-Arrastia, R. Archives of neurology 2008 65 5 619
- Neurological Autoantibody Prevalence in Epilepsy of Unknown Etiology.
  Dubey D, Alqallaf A, Hays R, Freeman M, Chen K, Ding K, Agostini M, Vernino S JAMA neurology 2017 Feb

Research

Post-Traumatic Epilepsy
ICU EEG Monitoring
Epilepsy Surgery
Clinical Neurophysiology
Cerebral Functional Connectivity

Clinical Focus

Epilepsy & Seizures