Kathleen Zhang, M.D.

Harold C. Simmons Comprehensive Cancer Center

Internal Medicine - Cardiology
Cardio-oncology
Cancer Survivorship

New Patient Appointment Accepting Virtual Visits or 214-645-8000

Biography

Kathleen Zhang, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. She specializes in the cardiovascular care of patients with cancer (cardio-oncology).

Dr. Zhang earned her medical degree at the University of Pennsylvania, where she also completed her residency in internal medicine. She received advanced training in cardiology and cardio-oncology through fellowships at Washington University School of Medicine in St. Louis.

Certified by the American Board of Internal Medicine in internal medicine and cardiovascular disease and by the National Board of Echocardiography in adult comprehensive echocardiography, she joined the UT Southwestern faculty in 2022.

Dr. Zhang’s clinical and research interests focus on the cardiovascular care of cancer patients before, during, and after cancer treatment. She is a Fellow of the American College of Cardiology and International Cardio-Oncology Society.

The author of numerous academic articles, book chapters, and presentations, Dr. Zhang is co-editor of the Washington Manual of Cardio-Oncology and an associate editor of the International Cardio-Oncology Society Board Review Manual: A Guide to Cardio-Oncology. She serves as an ad-hoc reviewer for several journals, including Heart, Journal of Cardiac Failure, and Journal of the American College of Cardiology: Cardio-Oncology.

Education & Training

Fellowship - Barnes-Jewish Hospital/Washington University School of Medicine (2016-2019), Cardiology
Residency - Hospital of the University of Pennsylvania (2013-2016), Internal Medicine
Medical School - Perelman School of Medicine at the University of Pennsylvania (2009-2013)

Professional Associations & Affiliations

American College of Cardiology
American Heart Association
International Cardio-Oncology Society

Honors & Awards

Top Doctor 2021, Castle Connolly
Rising Star 2021, Castle Connolly
Alpha Omega Alpha Honor Medical Society 2013, University of Pennsylvania
Phi Beta Kappa Honor Society 2009, Stanford University

Books & Publications

Books
- The Washington Manual of Cardio-Oncology. 1st edition
  Lenihan DJ, Mitchell JD, Zhang KW eds. (in press), Philadelphia, PA, Lippincott Williams & Wilkins
- International Cardio-Oncology Society Board Review Manual: A Guide to Cardio-Oncology
  Lenihan DJ, Alvarez-Cardona JA, Baliga R eds., Zhang KW: Associate Editor (2020), Tampa, FL
- Cardiac Amyloidosis in The Washington Manual of Cardiology Subspecialty Consult. 4th edition
  Zhang KW, Lenihan DJ (in press), Philadelphia, PA, Lippincott Williams & Wilkins
- Cardiac Dysfunction: Traditional Chemotherapy, HER2-Based Therapy, and Radiation in The Washington Manual of Cardio-Oncology. 1st edition
  Vallabhaneni S, Krone RJ, Zhang KW (in press), Philadelphia, PA, Lippincott Williams & Wilkins
- Valvular Disease in The Washington Manual of Cardio-Oncology. 1st edition
  Rivera Maza M, Zhang KW, Quader N (in press), Philadelphia, PA, Lippincott Williams & Wilkins
- Hypertension in The Washington Manual of Cardio-Oncology. 1st edition
  Ramayya T, Zhang KW (in press), Philadelphia, PA, Lippincott Williams & Wilkins
- Cardiac Amyloidosis: General Approach to Diagnosis in The Washington Manual of Cardio-Oncology. 1st edition
  Schiffer W, Zhang KW (in press), Philadelphia, PA, Lippincott Williams & Wilkins
Publications
- Echocardiographic and clinical predictors of cardiac amyloidosis: limitations of apical sparing.
  Kyrouac D, Schiffer W, Lennep B, Fergestrom N, Zhang KW, Gorcsan J, Lenihan DJ, Mitchell JD, ESC heart failure 2021 Dec
- Role of cardiovascular magnetic resonance in early detection and treatment of cardiac dysfunction in oncology patients.
  Vallabhaneni S, Zhang KW, Alvarez-Cardona JA, Mitchell JD, Steen H, Woodard PK, Lenihan DJ, The international journal of cardiovascular imaging 2021 Oct 37 10 3003-3017
- Cardiovascular Events in Men with Prostate Cancer Receiving Hormone Therapy: An Analysis of the FDA Adverse Event Reporting System (FAERS).
  Zhang KW, Reimers MA, Calaway AC, Fradley MG, Ponsky L, Garcia JA, Cullen J, Baumann BC, Addison D, Campbell CM, Ghosh AK, Lenihan DJ, Desai NR, Weintraub N, Guha A, The Journal of urology 2021 09 206 3 613-622
- Prognostic Utility of Echocardiographic Atrial and Ventricular Strain Imaging in Patients With Cardiac Amyloidosis.
  Huntjens PR, Zhang KW, Soyama Y, Karmpalioti M, Lenihan DJ, Gorcsan J, JACC. Cardiovascular imaging 2021 08 14 8 1508-1519
- Interim Analysis of the Phase II Study: Noninferiority Study of Doxorubicin with Upfront Dexrazoxane plus Olaratumab for Advanced or Metastatic Soft-Tissue Sarcoma.
  Van Tine BA, Hirbe AC, Oppelt P, Frith AE, Rathore R, Mitchell JD, Wan F, Berry S, Landeau M, Heberton GA, Gorcsan J, Huntjens PR, Soyama Y, Vader JM, Alvarez-Cardona JA, Zhang KW, Lenihan DJ, Krone RJ, Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jul 27 14 3854-3860
- Cardiac Amyloidosis for the Primary Care Provider: A Practical Review to Promote Earlier Recognition of Disease.
  Zhang KW, Vallabhaneni S, Alvarez-Cardona JA, Krone RJ, Mitchell JD, Lenihan DJ, The American journal of medicine 2021 05 134 5 587-595
- Heart Failure With Targeted Cancer Therapies: Mechanisms and Cardioprotection.
  Hahn VS, Zhang KW, Sun L, Narayan V, Lenihan DJ, Ky B, Circulation research 2021 05 128 10 1576-1593
- Out of the woods, but still in the weeds: When cancer therapy becomes part of a chronic condition.
  Zhang KW, Heart (British Cardiac Society) 2021 04 107 8 607-608
- A multi-modal diagnostic model improves detection of cardiac amyloidosis among patients with diagnostic confirmation by cardiac biopsy.
  Zhang KW, Zhang R, Deych E, Stockerl-Goldstein KE, Gorcsan J, Lenihan DJ, American heart journal 2021 02 232 137-145
- Coronary and aortic calcification are associated with cardiovascular events on immune checkpoint inhibitor therapy.
  Schiffer WB, Deych E, Lenihan DJ, Zhang KW, International journal of cardiology 2021 01 322 177-182
- Unsupervised cluster analysis of patients with recovered left ventricular ejection fraction identifies unique clinical phenotypes.
  Perry A, Loh F, Adamo L, Zhang KW, Deych E, Foraker R, Mann DL, PloS one 2021 16 3 e0248317
- Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology.
  Alvarez-Cardona JA, Zhang KW, Mitchell JD, Zaha VG, Fisch MJ, Lenihan DJ, JACC. CardioOncology 2020 Dec 2 5 791-794
- Cardiac Amyloidosis: More Than a Needle in a Haystack.
  Joynt Maddox KE, Zhang KW, JACC. CardioOncology 2020 Dec 2 5 719-720
- Coronary heart disease and mortality following a breast cancer diagnosis.
  Guo A, Zhang KW, Reynolds K, Foraker RE, BMC medical informatics and decision making 2020 05 20 1 88
- Apical Sparing Pattern of Longitudinal Strain and Positive Bone Scintigraphy in Metastatic Myocardial Calcification.
  Zhang KW, Sadhu JS, Miller BW, Brennan DC, Bierhals AJ, Chen JF, Lin CY, Vader JM, JACC. Case reports 2020 May 2 5 809-813
- Plasma Hepatocyte Growth Factor for Diagnosis and Prognosis in Light Chain and Transthyretin Cardiac Amyloidosis.
  Zhang KW, Miao J, Mitchell JD, Alvarez-Cardona J, Tomasek K, Su YR, Gordon M, Cornell RF, Lenihan DJ, JACC. CardioOncology 2020 Mar 2 1 56-66
- Cardiovascular Complications of Prostate Cancer Therapy
  Campbell CM, Zhang KW, Ponsky L, Collier A, Linch M, Guha A, Ghosh AK Curr Treat Options Cardio Med 2020 22 69
- Emerging Therapeutics for the Treatment of Light Chain and Transthyretin Amyloidosis.
  Zhang KW, Stockerl-Goldstein KE, Lenihan DJ, JACC. Basic to translational science 2019 Jun 4 3 438-448
- Abnormalities in 3-Dimensional Left Ventricular Mechanics With Anthracycline Chemotherapy Are Associated With Systolic and Diastolic Dysfunction.
  Zhang KW, Finkelman BS, Gulati G, Narayan HK, Upshaw J, Narayan V, Plappert T, Englefield V, Smith AM, Zhang C, Hundley WG, Ky B, JACC. Cardiovascular imaging 2018 08 11 8 1059-1068
- Cancer and cardiovascular disease: the use of novel echocardiography measures to predict subsequent cardiotoxicity in breast cancer treated with anthracyclines and trastuzumab.
  Gulati G, Zhang KW, Scherrer-Crosbie M, Ky B, Current heart failure reports 2014 Dec 11 4 366-73
- Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure.
  Zhang KW, French B, May Khan A, Plappert T, Fang JC, Sweitzer NK, Borlaug BA, Chirinos JA, St John Sutton M, Cappola TP, Ky B, Journal of the American Heart Association 2014 Jan 3 1 e000550
- Safety of minimal immunosuppression in liver transplantation for hepatoblastoma.
  Suh MY, Wang K, Gutweiler JR, Misra MV, Krawczuk LE, Jenkins RL, Lillehei CW, Jonas MM, Kim HB, Journal of pediatric surgery 2008 Jun 43 6 1148-52

Research

Cardio-oncology
Echocardiography

Clinical Focus

Cardio-oncology
Cancer Survivorship
Cardiac Imaging
General Cardiology