- Residency - Henry Ford Health Systems (1986-1990), Psychiatry
- Medical School - Baroda Medical College (1976-1980)
- Internship - S.S. General Hospital (1980-1981), Psychiatry
- Residency - University General Hospital (1982-1985), Psychiatry
- Fellowship - UT Southwestern Medical Center (1990-1993), Psychiatry
Madhukar Trivedi, M.D.
- Betty Jo Hay Distinguished Chair in Mental Health
- Julie K. Hersh Chair for Depression Research and Clinical Care
Madhukar H. Trivedi, M.D., is a Professor in the Department of Psychiatry at UT Southwestern Medical Center. He serves as Chief of the Division of Mood Disorders and the founding Director of the Center for Depression Research and Clinical Care, where he holds the Betty Jo Hay Distinguished Chair in Mental Health and the Julie K. Hersh Chair for Depression Research and Clinical Care. He specializes in treating depression.
Dr. Trivedi earned his medical degree at Baroda Medical College in India, where he also completed a residency in psychiatry. He performed a second residency in psychiatry at Henry Ford Hospital in Detroit, Michigan, and received advanced training in functional brain imaging and psychopharmacology through a research fellowship at UT Southwestern.
Certified by the American Board of Psychiatry and Neurology, Dr. Trivedi joined the UT Southwestern faculty in 1993.
Dr. Trivedi is an internationally recognized translational researcher focusing on developing and validating biosignatures of depression. He also conducts research on pharmacological, psychosocial, and nonpharmacological treatments for depression. He has been a principal investigator on numerous translational research projects as well as clinical trials; has authored more than 500 peer-reviewed scholarly articles, numerous abstracts, and book chapters; and has delivered more than 200 invited lectures. He serves on the editorial board of CNS Spectrums, Clinical Medicine: Psychiatry, Journal of Clinical Psychiatry, Journal of Affective Disorders, Psychiatric Annals and Asian Journal of Psychiatry. He is an ad hoc reviewer for several journals.
Dr. Trivedi is President-Elect of the American Society of Clinical Psychopharmacology and a member of numerous other professional organizations, including the American College of Neuropsychopharmacology, the American College of Psychiatrists, the American Medical Association, the American Psychiatric Association, the Dallas County Medical Society, the Society of Biological Psychiatry, the Texas Medical Association, and the Texas Society of Psychiatric Physicians.
He has been named a Texas Monthly Super Doctor multiple times, including in 2018, and has received numerous local and international accolades, including the Gerald L. Klerman Award from the National Depressive and Manic-Depressive Association Scientific Advisory Board, the Psychiatric Excellence Award from the Texas Society of Psychiatric Physicians, the Gerald Klerman Senior Investigator Award, the American Psychiatric Association Award for Research, and the Mood Disorders Research Award from the American College of Psychiatrists. Dr. Trivedi was listed by Thomson Reuters’ World’s Most Influential Scientific Minds as one of the nation’s most highly cited researchers in psychiatry in 2014, 2015, and 2017.
- ACNP American College of Neuropsychopharmacology
- American Psychiatric Association
- Texas Indo-American Physicians Society
- Texas Medical Association
- Texas Society of Psychiatric Physicians
- Outstanding Academician Award 2005, Indo American Psychiatric Association (IAPA)
- Honorary International Advisory Member 2002, The Chinese Pharmacology Algorithm Project
- Psychiatric Excellence Award 2002, Texas Society of Psychiatric Physicians (TSPP)
- Gerald L. Klerman Young Investigator Award 2000, National Depressive and Manic-Depressive Association Scientific Advisory Board
- Depression Specific Content Expert, Evidence Based Report Center (San Antonio) 1997, Agency for Health Care Policy and Research , U.S. Dept of Health and Human Services
Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression
Rush, A.J., Trivedi, M.H., Wisniewski, S.R., Stewart, J.W., Nierenberg, A., Thase, M.E., Ritz, L., Biggs, M.M., Warden, D., Luther, J.F., Shores-Wilson, K., Niederehe, G., Fava, M. New England Journal of Medicine Spring 2006 354 1231-42
Medication Augmentation after the Failure of SSRIs for Depression
Trivedi, M.H., Fava, M., Wisniewski, S.R., Thase, M.E., Quitkin, F., Warden, D., Ritz, L., Nierenberg, A.A., Lebowitz, B.D., Biggs, M.M., Luther, J. F., Shores-Wilson, K., Rush, A.J. New England Journal of Medicine Spring 2006 354 1243-52
Evidence-based recommendations for the prescription of exercise for major depressive disorder.
Rethorst CD, Trivedi MH Journal of psychiatric practice 2013 May 19 3 204-12
Increase in work productivity of depressed individuals with improvement in depressive symptom severity.
Trivedi MH, Morris DW, Wisniewski SR, Lesser I, Nierenberg AA, Daly E, Kurian BT, Gaynes BN, Balasubramani GK, Rush AJ The American journal of psychiatry 2013 Jun 170 6 633-41
Modeling predictors, moderators and mediators of treatment outcome and resistance in depression.
Trivedi MH Biological psychiatry 2013 Jul 74 1 2-4
Clinical and sociodemographic characteristics associated with suicidal ideation in depressed outpatients.
Trivedi MH, Morris DW, Wisniewski SR, Nierenberg AA, Gaynes BN, Kurian BT, Warden D, Stegman D, Shores-Wilson K, Rush AJ Canadian journal of psychiatry. Revue canadienne de psychiatrie 2013 Feb 58 2 113-22
Exercise as an augmentation treatment for nonremitted major depressive disorder: a randomized, parallel dose comparison.
Trivedi MH, Greer TL, Church TS, Carmody TJ, Grannemann BD, Galper DI, Dunn AL, Earnest CP, Sunderajan P, Henley SS, Blair SN The Journal of clinical psychiatry 2011 May 72 5 677-84
Concise associated symptoms tracking scale: a brief self-report and clinician rating of symptoms associated with suicidality.
Trivedi MH, Wisniewski SR, Morris DW, Fava M, Kurian BT, Gollan JK, Nierenberg AA, Warden D, Gaynes BN, Luther JF, A John R The Journal of clinical psychiatry 2011 Jun 72 6 765-74
Concise Health Risk Tracking scale: a brief self-report and clinician rating of suicidal risk.
Trivedi MH, Wisniewski SR, Morris DW, Fava M, Gollan JK, Warden D, Nierenberg AA, Gaynes BN, Husain MM, Luther JF, Zisook S, Rush AJ The Journal of clinical psychiatry 2011 Jun 72 6 757-64
The current crisis of confidence in antidepressants.
Nierenberg AA, Leon AC, Price LH, Shelton RC, Trivedi MH The Journal of clinical psychiatry 2011 Jan 72 1 27-33
Stimulant reduction intervention using dosed exercise (STRIDE) - CTN 0037: study protocol for a randomized controlled trial.
Trivedi MH, Greer TL, Grannemann BD, Church TS, Somoza E, Blair SN, Szapocznik J, Stoutenberg M, Rethorst C, Warden D, Ring KM, Walker R, Morris DW, Kosinski AS, Kyle T, Marcus B, Crowell B, Oden N, Nunes E Trials 2011 12 206
Psychosocial outcomes in patients with recurrent major depressive disorder during 2 years of maintenance treatment with venlafaxine extended release.
Trivedi MH, Dunner DL, Kornstein SG, Thase ME, Zajecka JM, Rothschild AJ, Friedman ES, Shelton RC, Keller MB, Kocsis JH, Gelenberg A Journal of affective disorders 2010 Nov 126 3 420-9
Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death.
Hedayati SS, Minhajuddin AT, Afshar M, Toto RD, Trivedi MH, Rush AJ JAMA : the journal of the American Medical Association 2010 May 303 19 1946-53
Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder.
Papakostas GI, Fava M Dialogues in clinical neuroscience 2008 10 4 439-51
Factors Associated with Health-Related Quality of Life Among Outpatients with Major Depressive Disorder: A STARD Report.
Trivedi, M.H., Rush, A.J., Wisniewski, S.R., Warden, D., McKinney, W., Downing, M., Berman, S.R., Farabaugh, A., Luther, J., Nierenberg, A.A., Lis, J., Sackeim, H. The Journal of Clinical Psychiatry 2006 67(2) 185-95.
Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice
Trivedi, M.H., Rush, A.J., Wisniewski, S.R., Nierenberg, A.A., Warden, D., Ritz, L, Norquist, G., Howland, R.H., McGrath, P.J., Shores-Wilson, K., Biggs, M.M., Balasubramani, G.K., Fava, M. The American Journal of Psychiatry 2006 163(1) 28-40
Recent Advances in the Treatment of Depression in the Presence of Physical Symptoms
Trivedi, M.H., Katon, W.J., Daly, E., Clayton, A.H., Frank, E. The Journal of Clinical Psychiatry 2006 67(2) 310-21
Exercise as an Augmentation Strategy for Treatment of Major Depression.
Trivedi, M.H., Greer, T.L., Grannemann, B.D., Chambliss, H.O., Jordan, A.N Journal of Psychiatric Practice 2006 12(4) 205-13
Use of Treatment Algorithms for Depression
Trivedi, M.H., Fava, M., Marangell, L.B., Osser, D.N., Shelton, R.C. Journal of Clinical Psychiatry 2006 67(9) 1458-65
The Texas Medication Algorithm Project (TMAP): Clinical Results for Patients with Major Depressive Disorder
Trivedi, M.H., Rush, A.J., Crismon, M.L., Kashner, T.M., Toprac, M.G., Carmody, T.J., Key, T., Biggs, N.M., Shores-Wilson, K., Witte, B, Suppes, T., Miller, A.L., Altshuler, K.Z., and Shon, S.P. Archives of General Psychiatry 2004 61(7) 669-680
Do Bupropion SR and Sertraline Differ in Their Effects on Anxiety in Depressed Patients
Trivedi MH, Rush AJ, Carmody TJ, Donahue RMJ, Bolden-Watson C, Houser TL, Metz A. Journal of Clinical Psychiatry 2001 62(10) 776-781
Which Depressed Patients Respond to Nefazodone and When?
Trivedi MH, Rush AJ, Pan Ji-Yang, Carmody TJ. Journal of Clinical Psychiatry 2001 62(3) 158-163
- Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression
- Evidence based psychopharmacology and treatment algorithms in Mood Disorders
- Functional Brain Imaging in Major Depressive and Obsessive Compulsive Disorders
- Neurobiology and Psychopharmacology of Depression and Bipolar Disorder