Michael Dohopolski, M.D.

Radiation Oncology
Brain Tumors
Central Nervous System Tumors

New Patient Appointment Accepting Virtual Visits or 214-645-8525

Biography

Michael Dohopolski, M.D., is an Assistant Professor in the Department of Radiation Oncology at UT Southwestern Medical Center. He specializes in treating central nervous system malignancies with stereotactic radiosurgery (SRS) and image-guided radiation therapy (IGRT) for brain tumors and cancers of the spinal cord. He also has expertise in the use of brachytherapy for ocular cancer, gliomas and meningiomas.

Dr. Dohopolski earned his medical degree at the University of Pittsburgh School of Medicine. He completed a residency in radiation oncology at UT Southwestern, where he served as Chief Resident and worked on advanced computer techniques to create an artificial intelligence model to identify cancer, which has been implemented successfully in two clinical trials.

He joined the UT Southwestern faculty in 2023.

Dr. Dohopolski is a member of several professional organizations, including the American Society of Clinical Oncology, the Radiological Society of North America (RSNA), and the American Society for Radiation Oncology. Additionally, he serves on the trainee editorial board for Radiology: Artificial Intelligence.

He has delivered scores of presentations, contributed to the book Decision Making in Otolaryngology, and published numerous peer-reviewed academic articles, many related to machine learning and neural networks.

Among his many accolades, Dr. Dohopolski has received the Roentgen Resident/Fellow Research Award from the RSNA and the Dean’s Scholar in Clinical Research Program Award from UT Southwestern.

Personal Note

When he is not at work, Dr. Dohopolski enjoys spending time with his family, playing golf, and computer coding.

Education & Training

Medical School - University of Pittsburgh School of Medicine (2014-2018)
Residency - University of Texas Medical Center at Dallas (2019-2023), Radiation Oncology
Internship - Banner University Medical Center Phoenix (2018-2019), Medical Education

Professional Associations & Affiliations

American Society of Clinical Oncology
American Society for Radiation Oncology
Radiological Society of North America

Honors & Awards

Roentgen Resident/Fellow Research Award 2023, Radiological Society of North America
Dean’s Scholar in Clinical Research Program Award 2023-2026, UT Southwestern
Editor’s Recognition Award for reviewing with Distinction 2022, Radiology: Artificial Intelligence
Chief Resident 2021-2022, UT Southwestern Residency in Radiation Oncology
Travel Award 2022, ECOG-ACRIN Cancer Research Group Spring Meeting
Brown Family Award for Residence Excellence Nominee 2022, Texas Radiological Society Foundation
Holman Research Pathway 2020-2022, American Board of Radiology
Radiation Oncology Research Award 2018, University of Pittsburgh School of Medicine

Books & Publications

Books
- Radiotherapy for head and neck cancer in Decision Making in Otolaryngology (2nd revised ed.)
  Dohopolski M, Clump DA (2019), New Delhi, India, Jaypee Brothers Medical Publishers
Publications
- In silico evaluation and feasibility of near margin-less head and neck daily adaptive radiotherapy
  Dohopolski M, Visak J, Choi B, Meng B, Parsons D, Zhong X, Inam E, Avkshtol V, Moon D, Sher D, Lin MH Radiotherapy and Oncology 2024 Aug 197
- Progressive auto-segmentation for cone-beam computed tomography-based online adaptive radiotherapy
  Zhao H, Liang X, Meng B, Dohopolski M, Choi B, Cai B, Lin MH, Bai T, Nguyen D, Jiang S Physics and Imaging in Radiation Oncology 2024 Jul 31
- Performance deterioration of deep learning models after clinical deployment: a case study with auto-segmentation for definitive prostate cancer radiotherapy
  Wang B, Dohopolski M, Bai T, Wu J, Hannan R, Desai N, Garant A, Yang D, Nguyen D, Lin MH, Timmerman R, Wang X, Jiang SB Machine Learning: Science and Technology 2024 Jun 5
- Deep learning based automatic segmentation of the Internal Pudendal Artery in definitive radiotherapy treatment planning of localized prostate cancer
  Balagopal A, Dohopolski M, Suk Kwon Y, Montalvo S, Morgan H, Bai T, Nguyen D, Liang X, Zhong X, Lin MH, Desai N, Jiang S Physics and Imaging in Radiation Oncology 2024 Apr 30
- Harnessing uncertainty in radiotherapy auto-segmentation quality assurance
  Wahid KA, Sahlsten J, Jaskari J, Dohopolski MJ, Kaski K, He R, Glerean E, Kann BH, Mäkitie A, Fuller CD, Naser MA, Fuentes D Physics and Imaging in Radiation Oncology 2024 Jan 29
- The accuracy of artificial intelligence deformed nodal structures in cervical online cone-beam-based adaptive radiotherapy
  Wang E, Yen A, Hrycushko B, Wang S, Lin J, Zhong X, Dohopolski M, Nwachukwu C, Iqbal Z, Albuquerque K Physics and Imaging in Radiation Oncology 2024 Jan 29
- Efficacy and Quality-of-Life Following Involved Nodal Radiotherapy for Head and Neck Squamous Cell Carcinoma: The INRT-AIR Phase II Clinical Trial
  Sher DJ, Moon DH, Vo D, Wang J, Chen L, Dohopolski M, Hughes R, Sumer BD, Ahn C, Avkshtol V Clinical Cancer Research 2023 Sep 29 3284-3291
- Long-term Patient-Reported Outcomes in a Population-Based Cohort Following Radiotherapy vs Surgery for Oropharyngeal Cancer
  Dohopolski MJ, Diao K, Hutcheson KA, Akhave NS, Goepfert RP, He W, Lei XJ, Peterson SK, Shen Y, Sumer BD, Smith BD, Sher DJ JAMA Otolaryngology - Head and Neck Surgery 2023 Aug 149 697-707
- ARMO: automated and reliable multi-objective model for lymph node metastasis prediction in head and neck cancer
  Zhou Z, Chen L, Dohopolski M, Sher D, Wang J Physics in medicine and biology 2023 May 68
- Towards reliable head and neck cancers locoregional recurrence prediction using delta-radiomics and learning with rejection option
  Wang K, Dohopolski M, Zhang Q, Sher D, Wang J Medical physics 2023 Apr 50 2212-2223
- Deep learning based direct segmentation assisted by deformable image registration for cone-beam CT based auto-segmentation for adaptive radiotherapy
  Liang X, Morgan H, Bai T, Dohopolski M, Nguyen D, Jiang S Physics in medicine and biology 2023 Feb 68
- Recurrence-Free Survival Prediction Under the Guidance of Automatic Gross Tumor Volume Segmentation for Head and Neck Cancers
  Wang K, Li Y, Dohopolski M, Peng T, Lu W, Zhang Y, Wang J 2023 144-153
- Artificial Intelligence–Empowered Radiation Oncology Residency Education
  Kwon YS, Dohopolski M, Morgan H, Garant A, Sher D, Rahimi A, Sanford NN, Vo D, Albuquerque K, Kumar K, Timmerman R, Jiang SB Practical Radiation Oncology 2023 Jan 13 8-10
- Case study: Lymph node malignancy classification for head and neck cancer radiation therapy
  Wang J, Chen L, Dohopolski M, Sher D 2023 Jan 401-423
- A Proof-of-Concept Study of Artificial Intelligence– assisted Contour Editing
  Bai T, Balagopal A, Dohopolski M, Morgan HE, McBeth R, Tan J, Lin MH, Sher DJ, Nguyen D, Jiang S Radiology: Artificial Intelligence 2022 Sep 4
- Real-time MRI motion estimation through an unsupervised k-space-driven deformable registration network (KS-RegNet)
  Shao HC, Li T, Dohopolski MJ, Wang J, Cai J, Tan J, Wang K, Zhang Y Physics in medicine and biology 2022 Jul 67
- Use of deep learning to predict the need for aggressive nutritional supplementation during head and neck radiotherapy
  Dohopolski M, Wang K, Morgan H, Sher D, Wang J Radiotherapy and Oncology 2022 Jun 171 129-138
- Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer
  Hannan R, Dohopolski MJ, Pop LM, Mannala S, Watumull L, Womack KB, Gao A, Garant A, Arriaga YE, Bowman I, Chung J, Wang J, Ariizumi K, Ahn C, Timmerman R, Courtney K Biomedicines 2022 Jun 10
- Dose-Intensified Stereotactic Ablative Radiation for Localized Prostate Cancer
  Chen L, Gannavarapu BS, Desai NB, Folkert MR, Dohopolski M, Gao A, Ahn C, Cadeddu J, Bagrodia A, Woldu S, Raj GV, Roehrborn C, Lotan Y, Timmerman RD, Garant A, Hannan R Frontiers in Oncology 2022 Feb 12
- Exploratory ensemble interpretable model for predicting local failure in head and neck cancer: The additive benefit of CT and intra-treatment cone-beam computed tomography features
  Morgan HE, Wang K, Dohopolski M, Liang X, Folkert MR, Sher DJ, Wang J Quantitative Imaging in Medicine and Surgery 2021 Dec 11 4781-4796
- PSA-Net: Deep learning–based physician style–aware segmentation network for postoperative prostate cancer clinical target volumes
  Balagopal A, Morgan H, Dohopolski M, Timmerman R, Shan J, Heitjan DF, Liu W, Nguyen D, Hannan R, Garant A, Desai N, Jiang S Artificial Intelligence in Medicine 2021 Nov 121
- Radiation therapy in non-small-cell lung cancer
  Dohopolski M, Gottumukkala S, Gomez D, Iyengar P Cold Spring Harbor Perspectives in Medicine 2021 Oct 11
- A deep learning-based framework for segmenting invisible clinical target volumes with estimated uncertainties for post-operative prostate cancer radiotherapy
  Balagopal A, Nguyen D, Morgan H, Weng Y, Dohopolski M, Lin MH, Barkousaraie AS, Gonzalez Y, Garant A, Desai N, Hannan R, Jiang S Medical Image Analysis 2021 Aug 72
- Future Directions in the Use of SAbR for the Treatment of Oligometastatic Cancers
  Morris Z, Dohopolski M, Rahimi A, Timmerman R Seminars in Radiation Oncology 2021 Jul 31 253-262
- Attention Guided Lymph Node Malignancy Prediction in Head and Neck Cancer
  Chen L, Dohopolski M, Zhou Z, Wang K, Wang R, Sher D, Wang J International Journal of Radiation Oncology Biology Physics 2021 Jul 110 1171-1179
- Oligometastatic non-small cell lung cancer: A narrative review of stereotactic ablative radiotherapy
  Dohopolski M, Iyengar P Annals of palliative medicine 2021 May 10 5944-5953
- Predicting lymph node metastasis in patients with oropharyngeal cancer by using a convolutional neural network with associated epistemic and aleatoric uncertainty
  Dohopolski M, Chen L, Sher D, Wang J Physics in medicine and biology 2020 Nov 65
- The reintroduction of radiotherapy into the integrated management of kidney cancer
  Dohopolski M, Hannan R, Wardak Z, Hammers H, Garant A Cancer Journal 2020 Sep 26 448-459
- Reliable lymph node metastasis prediction in head neck cancer through automated multi-objective model
  Zhou Z, Dohopolski M, Chen L, Chen X, Jiang S, Sher D, Wang J 2019 May
- The Prognostic Significance of p16 Status in Patients With Vulvar Cancer Treated With Vulvectomy and Adjuvant Radiation
  Dohopolski MJ, Horne ZD, Pradhan D, Bhargava R, Edwards RP, Kelley JL, Comerci JT, Olawaiye AB, Courtney-Brooks M, Berger JL, Sukumvanich P, Beriwal S International Journal of Radiation Oncology Biology Physics 2019 Jan 103 152-160
- Human papillomavirus infection mediates response and outcome of vulvar squamous cell carcinomas treated with radiation therapy
  Horne ZD, Dohopolski MJ, Pradhan D, Bhargava R, Edwards RP, Kelley JL, Comerci JT, Olawaiye AB, Courtney-Brooks MB, Bockmeier MM, Berger JL, Taylor SE, Sukumvanich P, Beriwal S Gynecologic oncology 2018 Oct 151 96-101
- Thoracic reirradiation with SBRT for residual/recurrent and new primary NSCLC within or immediately adjacent to a prior high-dose radiation field
  Horne ZD, Dohopolski MJ, Clump DA, Burton SA, Heron DE Practical Radiation Oncology 2018 May 8 e117-e123
- Single-institutional outcomes of adjuvant brachytherapy for Stage I endometrial cancer—Are outcomes consistent with randomized studies?
  Dohopolski MJ, Horne ZD, Gebhardt BJ, Glaser SM, Edwards RP, Kelley JL, Comerci JT, Olawaiye AB, Courtney-Brooks M, Berger JL, Sukumvanich P, Beriwal S Brachytherapy 2018 May 17 564-570
- Stereotactic body radiation therapy for isolated hilar and mediastinal non-small cell lung cancers
  Horne ZD, Richman AH, Dohopolski MJ, Clump DA, Burton SA, Heron DE Lung Cancer 2018 Jan 115 1-4
- Stereotactic body radiotherapy for locally-advanced unresectable pancreatic cancer - Patterns of care and overall survival
  Dohopolski MJ, Glaser SM, Vargo JA, Balasubramani GK, Beriwal S Journal of Gastrointestinal Oncology 2017 Oct 8 766-777
- Glioblastoma multiforme (GBM) in the elderly: initial treatment strategy and overall survival
  Glaser SM, Dohopolski MJ, Balasubramani GK, Flickinger JC, Beriwal S Journal of Neuro-Oncology 2017 Aug 134 107-118
- Brachytherapy boost for prostate cancer: Trends in care and survival outcomes
  Glaser SM, Dohopolski MJ, Balasubramani GK, Benoit RM, Smith RP, Beriwal S Brachytherapy 2017 Mar 16 330-341

Research

Adaptive radiation therapy
Artificial intelligence applications within medicine

Clinical Focus

Brain Tumors
Central Nervous System Tumors
Brain & Spinal Cord Cancer
Ocular Lymphoma
Ocular oncology