Ayeeshik Kole, M.D., Ph.D.

Ayeeshik Kole, M.D., Ph.D.

  • Internal Medicine - Cardiology
  • High Cholesterol and Lipid Disorders
  • Cardiovascular Risk Assessment

Biography

Ayeeshik Kole, M.D., Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He specializes in cardiovascular disease prevention.

Dr. Kole earned his medical degree at the Indiana University School of Medicine and his doctoral degree in biomedical engineering at Purdue University. He completed a residency in internal medicine at UT Southwestern Medical Center, where he also received advanced training through a cardiovascular disease fellowship.

Certified by the American Board of Internal Medicine, he joined the UT Southwestern faculty in 2026.

Dr. Kole’s areas of clinical specialization include:

  • High cholesterol and lipid disorders, including elevated lipoprotein(a)
  • Premature coronary artery disease and subclinical atherosclerosis
  • Cardiovascular risk assessment, particularly for patients with a strong family history of heart disease or abnormal coronary artery calcium or cardiac imaging
  • South Asian cardiovascular risk and heart health
  • Obesity and cardiometabolic risk

Dr. Kole is a member of numerous professional associations, including the American Society for Preventive Cardiology, the American Heart Association, and the Society of Cardiovascular Computed Tomography. He serves on national committees focused on cardiovascular imaging and prevention, including the American Heart Association Committee on Cardiac Imaging and Intervention and the American Society for Preventive Cardiology South Asian Cardiometabolic Health Working Group. He also serves as a junior editor of the Journal of Cardiovascular Computed Tomography.

Dr. Kole has published numerous peer-reviewed articles on cardiovascular prevention, coronary atherosclerosis, lipid management, and cardiovascular imaging, and has presented his work nationally and internationally, including through invited lectures and scientific presentations.

Personal Note

When he’s not at work, Dr. Kole enjoys spending time with his family and dog, and exploring new restaurants.

  • Graduate School - Purdue University (2014-2018)
  • Medical Education - Indiana University School of Medicine (2012-2020), MD
  • Residency - UT Southwestern Medical Center (2020-2023), Internal Medicine
  • Fellowship - UT Southwestern Medical Center (2023-2026), Cardiology Fellowship
  • American College of Cardiology
  • American Heart Association
  • American Society for Preventive Cardiology
  • International Society for Applied Cardiovascular Biology
  • National Lipid Association
  • Society of Cardiovascular Computed Tomography
  • Young Researcher Award 2026-2028, NewAmsterdam Pharma
  • Foster Fellow 2026, UT Southwestern Department of Internal Medicine
  • SANSAR/Burgundy Young Investigator Award 2024, South Asian Network Supporting Awareness and Research and South Asian Health Foundation
  • Coronary CT angiography and quantitative coronary plaque imaging
  • Subclinical and noncalcified coronary atherosclerosis
  • Artificial intelligence and quantitative cardiovascular imaging
  • Cardiovascular disease prevention in South Asian adults

Clinical Focus

  • High Cholesterol and Lipid Disorders
  • Cardiovascular Risk Assessment
  • Premature Coronary Artery Disease
  • Hypertension
  • Obesity and Cardiometabolic Risk

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