- Fellowship - Cleveland Clinic Foundation (2014), Epilepsy
- Residency - University of Pennsylvania (2013), Neurological Surgery
- Internship - University of Pennsylvania Health System (2007), General Surgery
- Medical School - Baylor College of Medicine (2006)
Bradley Lega, M.D.
- Peter O'Donnell Jr. Brain Institute
- Neurological Surgery
Meet Dr. Lega
As the surgical leader of UT Southwestern Medical Center’s comprehensive epilepsy program, one of the top programs in the world, Dr. Lega is recognized as a national expert in using stereoelectroencephalography, or stereo EEG to locate the origin of epileptic seizures in the brain. This can then help determine if a patient is a candidate for surgical treatment.
Revolutionizing Treatment Using Emerging Technologies
Through experience acquired through hundreds of epilepsy and tumor cases, Dr. Lega tailors his mapping and treatment strategies to the unique circumstances of each patient. This includes using new, less invasive techniques along with traditional surgical approaches.
“It’s an exciting time to be working in this field,” Dr. Lega says. “New tools, such as stereo EEG and NeuroPace, are giving options to patients who may have previously been told surgical treatments weren’t available to them. And laser interstitial therapy (LITT) has given us a less invasive option that is ideally suited to treating some patients with epilepsy and tumors.”
LITT is only available at UT Southwestern through Southwest Health Resources, and Dr. Lega is the only surgeon in North Texas who provides this therapy to patients with brain tumors and epilepsy.
“Laser therapy requires an expert team working together, and the close collaborative environment at UT Southwestern is really necessary for these complex cases. Brain tumors are often linked to seizures, and our integrated team provides the best approach for their treatment.”
This integrated approach also helps protect the brain’s vital functions, including memory, during a patient's treatment for tumors and epilepsy.
“Our team at UT Southwestern works with a group of leading centers across the country to understand memory and other cognitive functions, such as language processing. Our work has led to exciting breakthroughs,” Dr. Lega says.
Dr. Lega has been widely recognized for his contributions to understanding how the brain creates memories. “One day, we hope to restore memory function to patients in whom tumors or epilepsy have affected their brain. For now, this work has given me a deep understanding of how best to preserve these vital functions for patients who need surgery,” Dr. Lega says.
“With the tools we have at UT Southwestern, the expertise of our team, and our experience as one of the busiest centers in the country, I am proud to say that the care we provide patients with these conditions is truly top notch.”
Bradley Lega, M.D., is an Assistant Professor in the Department of Neurological Surgery at UT Southwestern Medical Center. He has secondary appointments in Neurology and Neurotherapeutics and Psychiatry.
Dr. Lega earned his undergraduate degree at Rice University and his medical degree at Baylor College of Medicine. He completed his neurological surgery residency at the University of Pennsylvania and received advanced training through a fellowship in epilepsy surgery at the Cleveland Clinic.
He offers patients access to emerging techniques for the treatment of epilepsy, brain tumors, and disorders of the spine. His area of specialty includes using novel brain mapping and computer-assisted navigation technologies to improve the safety and efficacy of neurosurgical procedures.
During his fellowship training at the Cleveland Clinic, Dr. Lega gained expertise in the use of stereo EEG, a technique used to identify whether patients with epilepsy are candidates for surgical treatment. He is one of only a handful of neurosurgeons in the country using this technique.
Dr. Lega’s research focuses on how brain conditions affect memory. The research he began at the University of Pennsylvania and that he continues at UT Southwestern focuses on preserving memory function and restoring memory to patients with brain injuries or brain tumors.
He is a member of several professional organizations, including the American Association of Neurological Surgeons, the Congress of Neurological Surgeons, and the Society for Neuroscience.
An essay concerning human understanding: how the cerebri anatome of Thomas Willis influenced John Locke.
Lega BC Neurosurgery 2006 Mar 58 3 567-76; discussion 567-76
Postoperative dural sinus thrombosis in a patient in a hypercoagulable state. Case report.
Lega BC, Yoshor D Journal of neurosurgery 2006 Nov 105 5 772-4
Recurrent hemifacial spasm following minor trauma: report of a case.
Lega BC, Harper RL, Dannenbaum MD, Yoshor D Stereotactic and functional neurosurgery 2008 86 6 394-6
Local cortical function after uncomplicated subdural electrode implantation. Laboratory investigation.
Yoshor D, Bosking WH, Lega BC, Sun P, Maunsell JH Journal of neurosurgery 2008 Jan 108 1 139-44
Microvascular decompression for hemifacial spasm: long-term results from 114 operations performed without neurophysiological monitoring.
Dannenbaum M, Lega BC, Suki D, Harper RL, Yoshor D Journal of neurosurgery 2008 Sep 109 3 410-5
Quality of life after hemicraniectomy for traumatic brain injury in adults. A review of the literature.
Danish SF, Barone D, Lega BC, Stein SC Neurosurgical focus 2009 Jun 26 6 E2
Cortical resection tailored to awake, intraoperative ictal recordings and motor mapping in the treatment of intractable epilepsia partialis continua: technical case report.
Lega BC, Wilfong AA, Goldsmith IL, Verma A, Yoshor D Neurosurgery 2009 Mar 64 3 Suppl ons195-6; discussion ons196
Isolated lower extremity monoplegia due to a traumatic intraparenchymal contusion: report of two cases.
Lega BC, Bailey RL, Kramer DR, Heuer GG, Chen JY, Schuster JM Brain injury : [BI] 2010 24 10 1231-5
Deep brain stimulation in the treatment of refractory epilepsy: update on current data and future directions.
Lega BC, Halpern CH, Jaggi JL, Baltuch GH Neurobiology of disease 2010 Jun 38 3 354-60
Choosing the best operation for chronic subdural hematoma: a decision analysis.
Lega BC, Danish SF, Malhotra NR, Sonnad SS, Stein SC Journal of neurosurgery 2010 Sep 113 3 615-21
Brain-machine interfaces: electrophysiological challenges and limitations.
Lega BC, Serruya MD, Zaghloul KA Critical reviews in biomedical engineering 2011 39 1 5-28
A patient with thoracic intradural disc herniation.
Whitmore RG, Williams BJ, Lega BC, Sanborn MR, Marcotte P Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2011 Dec 18 12 1730-2
Morphometric measurements of the anterior skull base for endoscopic transoral and transnasal approaches.
Lega BC, Kramer DR, Newman JG, Lee JY Skull base : official journal of North American Skull Base Society ... [et al.] 2011 Jan 21 1 65-70
Neuronal and oscillatory activity during reward processing in the human ventral striatum.
Lega BC, Kahana MJ, Jaggi J, Baltuch GH, Zaghloul K Neuroreport 2011 Nov 22 16 795-800
Human hippocampal theta oscillations and the formation of episodic memories.
Lega BC, Jacobs J, Kahana M Hippocampus 2012 Apr 22 4 748-61
Neuronal activity in the human subthalamic nucleus encodes decision conflict during action selection.
Zaghloul KA, Weidemann CT, Lega BC, Jaggi JL, Baltuch GH, Kahana MJ The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Feb 32 7 2453-60
Hemispheric malformations of cortical development: surgical indications and approach.
Lega B, Mullin J, Wyllie E, Bingaman W Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2014 Nov 30 11 1831-7
Slow-Theta-to-Gamma Phase-Amplitude Coupling in Human Hippocampus Supports the Formation of New Episodic Memories.
Lega B, Burke J, Jacobs J, Kahana MJ Cerebral cortex (New York, N.Y. : 1991) 2014 Oct
The gamma band effect for episodic memory encoding is absent in epileptogenic hippocampi.
Lega B, Dionisio S, Bingaman W, Najm I, Gonzalez-Martinez J Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2014 Sep
- An essay concerning human understanding: how the cerebri anatome of Thomas Willis influenced John Locke.
- Restoring memory function after brain injury
- Memory encoding and retrieval