- Fellowship - Cleveland Clinic Foundation (2015-2016), Advanced Heart Failure & Transplant Cardiology
- Graduate School - Harvard School of Public Health (2013-2015)
- Fellowship - Cleveland Clinic Foundation (2012-2015), Cardiovascular Disease
- Residency - UT Southwestern Medical School (2009-2012), Internal Medicine
- Medical School - UT Southwestern Medical School (2005-2009)
Justin Grodin, M.D.
- Internal Medicine - Cardiology
- Heart Transplant Medicine
Justin Grodin, M.D., is an Assistant Professor of Medicine in the UT Southwestern Department of Internal Medicine.
He earned his medical degree at UT Southwestern, where he also completed a residency in internal medicine. He performed two fellowships at the Cleveland Clinic, one in cardiovascular disease and one in advanced heart failure and transplant cardiology. Dr. Grodin also holds a master’s degree in public health from Harvard University.
Dr. Grodin specializes in caring for patients with end-stage heart failure, restrictive cardiomyopathies, hereditary cardiomyopathies, and hypertropic cardiomyopathies. His research interests include heart failure, the treatment of acute heart failure, cardiorenal syndrome, and metabolic and hemodynamic biomarkers of heart failure.
Dr. Grodin has numerous peer-reviewed publications in scientific journals. He serves as Co-Section Editor for the Current Heart Failure Reports’ “Biomarkers of Heart Failure” and as an ad-hoc reviewer for the Journal of Cardiac Failure, the Journal of the American College of Cardiology, the American Heart Journal, Circulation: Heart Failure, and reviews abstracts for the American College of Cardiology.
He is a member of the American College of Cardiology, the Heart Failure Society of America, and the Texas Medical Association.
Dr. Grodin is a native Texan and was born and raised in El Paso.
Meet Dr. Grodin
Heart Failure and Transplantation Specialist in Dallas
Justin Grodin, M.D., has specialty training in caring for people who are living with end-stage congestive heart failure. And he emphasizes the focus on living.
Dr. Grodin says, “I take a lot of pride in helping my patients understand their diagnosis, and in reassuring them that even though heart failure is serious, we’re going to make sure they’re getting the most thorough evaluation and best, individualized treatment.”
In severe cases, the treatment of advanced heart failure may require a heart transplant or a left ventricular assist device (LVAD), but Dr. Grodin says that medications and modifications in diet and lifestyle may be effective in delaying or even preventing major surgical interventions.
“For a portion of patients, the use of routine heart failure medications can actually improve cardiac function over time. In addition, there are novel disease-specific medications which may also treat specific heart conditions," Dr. Grodin says. Other patients benefit from minor surgical options, such as implantable defibrillators or pacemakers that resynchronize the heart.
In every case, Dr. Grodin takes his patients through a comprehensive evaluation to identify the best treatment approach. For people who need a transplant or an LVAD, Dr. Grodin walks them through the entire process, from the initial evaluation to the hospital and ICU, and then he continues to see them for follow-up care after surgery.
Answering an Increasing Epidemic
Dr. Grodin has a master’s degree in public health and specializes in clinical epidemiology. He leads research to improve our understanding of heart failure and to identify better treatments.
“Treatment for heart failure is continually evolving and we are constantly identifying clinical features which better our understanding of patient risk and may lead to individualized therapy,” he says.
The incidence of heart failure in the United States is increasing, which makes research even more important.
“We have a growing need for improved treatment options,” Dr. Grodin says. “Heart transplants are great, but we’re limited by the number of organs available. There are going to be more people needing better medical therapies, better LVADs, and other alternatives to transplants.”
Attention to the Details
Dr. Grodin joined the UT Southwestern faculty in 2016. In addition to treating patients with heart failure, he also cares for patients with cardiomyopathies and has significant experience with hypertrophic obstructive and nonobstructive cardiomyopathy.
No matter what heart issue he’s treating, Dr. Grodin says the best outcomes start with a meticulous, patient-centered approach to treatment.
“Sometimes heart failure is as bad as it sounds, but sometimes it might not be. When someone is frightened and you can offer reassurance, when someone is critically ill and you can offer a life-saving therapy, it’s incredibly gratifying.”
- American Heart Association (2010)
- American College of Cardiology (2012)
- Heart Failure Society of America (2013)
- International Society for Heart and Lung Transplantation (2016)
- Best Published Paper, UT Southwestern Internal Medicine Residency 2012
- Gus P. Karos Foundation Scholarship, Cleveland Clinic 2013
- Best Fellow In-Training Poster at the American College of Cardiology Scientific Sessions 2014
- The Lower Clinical Award, Cleveland Clinic 2016
Case Files in Cardiology
Faulx and Toy.(Ed.) (2015), McGraw-Hill Education
Cardiology: An Illustrated Textbook
Chatterjee(Ed.) (2016), Jaypee Brothers Medical Publishers
- Case Files in Cardiology
Variation of heart transplant rates in the united states during holidays.
Grodin JL, Ayers CR, Thibodeau JT, Mishkin JD, Mammen PP, Markham DW, Drazner MH, Patel PC Clinical transplantation 2014 Jun
Prognostic Role of Serum Chloride Levels in Acute Decompensated Heart Failure.
Grodin JL, Simon J, Hachamovitch R, Wu Y, Jackson G, Halkar M, Starling RC, Testani JM, Tang WH Journal of the American College of Cardiology 2015 Aug 66 6 659-66
Prognostic role of cardiac power index in ambulatory patients with advanced heart failure.
Grodin JL, Mullens W, Dupont M, Wu Y, Taylor DO, Starling RC, Tang WH European journal of heart failure 2015 Jul 17 7 689-96
A disproportionate elevation in right ventricular filling pressure, in relation to left ventricular filling pressure, is associated with renal impairment and increased mortality in advanced decompensated heart failure.
Grodin JL, Drazner MH, Dupont M, Mullens W, Taylor DO, Starling RC, Tang WH American heart journal 2015 Jun 169 6 806-12
Prognostic comparison of different sensitivity cardiac troponin assays in stable heart failure.
Grodin JL, Neale S, Wu Y, Hazen SL, Tang WH The American journal of medicine 2015 Mar 128 3 276-82
Circulating Kidney Injury Molecule-1 Levels in Acute Heart Failure: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).
Grodin JL, Perez AL, Wu Y, Hernandez AF, Butler J, Metra M, Felker GM, Voors AA, McMurray JJ, Armstrong PW, Califf RM, Starling RC, O'Connor CM, Tang WH JACC. Heart failure 2015 Oct 3 10 777-85
Pharmacologic Approaches to Electrolyte Abnormalities in Heart Failure.
Grodin JL Current heart failure reports 2016 Aug 13 4 181-9
Clinical Implications of Serum Albumin Levels in Acute Heart Failure: Insights From DOSE-AHF and ROSE-AHF.
Grodin JL, Lala A, Stevens SR, DeVore AD, Cooper LB, AbouEzzeddine OF, Mentz RJ, Groarke JD, Joyce E, Rosenthal JL, Vader JM, Tang WH Journal of cardiac failure 2016 Feb
Importance of Abnormal Chloride Homeostasis in Stable Chronic Heart Failure.
Grodin JL, Verbrugge FH, Ellis SG, Mullens W, Testani JM, Tang WH Circulation. Heart failure 2016 Jan 9 1 e002453
Intensification of Medication Therapy for Cardiorenal Syndrome in Acute Decompensated Heart Failure.
Grodin JL, Stevens SR, de Las Fuentes L, Kiernan M, Birati EY, Gupta D, Bart BA, Felker GM, Chen HH, Butler J, Dávila-Román VG, Margulies KB, Hernandez AF, Anstrom KJ, Tang WH Journal of cardiac failure 2016 Jan 22 1 26-32
Driving with the headlights on: Measuring adequate urinary sodium excretion on the road to precision diuresis.
Grodin JL, Tang WHW American heart journal 2018 May
Hyperkalemia in Heart Failure: Probably Not O"K".
Fudim M, Grodin JL, Mentz RJ Journal of the American Heart Association 2018 May 7 11
Association of Galectin-3 with Diabetes Mellitus in the Dallas Heart Study.
Vora A, de Lemos JA, Ayers C, Grodin JL, Lingvay I, The Journal of clinical endocrinology and metabolism 2019 Jun
Identifying a low-flow phenotype in heart failure with preserved ejection fraction: a secondary analysis of the RELAX trial.
Patel KV, Mauricio R, Grodin JL, Ayers C, Fonarow GC, Berry JD, Pandey A, ESC heart failure 2019 Apr
Dilemmas in the Dosing of Heart Failure Drugs: Titrating Diuretics in Chronic Heart Failure.
Pham D, Grodin JL Cardiac failure review 2017 Nov 3 2 108-112
Impact of Ultrafiltration on Serum Sodium Homeostasis and its Clinical Implication in Patients With Acute Heart Failure, Congestion, and Worsening Renal Function.
Kitai T, Grodin JL, Kim YH, Tang WH Circulation. Heart failure 2017 Feb 10 2 e003603
Circulating intestinal fatty acid-binding protein (I-FABP) levels in acute decompensated heart failure.
Kitai T, Kim YH, Kiefer K, Morales R, Borowski AG, Grodin JL, Tang WH Clinical biochemistry 2017 Feb
Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy.
Perez AL, Grodin JL, Wu Y, Hernandez AF, Butler J, Metra M, Felker GM, Voors AA, McMurray JJ, Armstrong PW, Starling RC, O'Connor CM, Tang WH European journal of heart failure 2016 Mar 18 3 290-7
Transient Hyponatremia During Hospitalization for Acute Heart Failure.
Verbrugge FH, Grodin JL, Mullens W, Taylor DO, Starling RC, Tang WH The American journal of medicine 2016 Jun 129 6 620-7
Prevalence and prediction of obstructive coronary artery disease in patients referred for valvular heart surgery.
Lappé JM, Grodin JL, Wu Y, Bott-Silverman C, Cho L The American journal of cardiology 2015 Jul 116 2 280-5
Worsening heart failure: challenges as a therapeutic target.
Tang WH, Grodin JL JACC. Heart failure 2015 May 3 5 404-7
Implications of Perceived Dyspnea and Global Well-Being Measured by Visual Assessment Scales During Treatment for Acute Decompensated Heart Failure.
Hendren NS, Drazner MH, Pandey A, Tang WHW, Grodin JL, The American journal of cardiology 2019 May
High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure.
Aimo A, Januzzi JL, Vergaro G, Ripoli A, Latini R, Masson S, Magnoli M, Anand IS, Cohn JN, Tavazzi L, Tognoni G, Gravning J, Ueland T, Nymo SH, Rocca HB, Bayes-Genis A, Lupón J, de Boer RA, Yoshihisa A, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Tentzeris I, Wilson Tang WH, Grodin JL, Passino C, Emdin M International journal of cardiology 2019 Feb 277 166-172
Prognostic implications of plasma volume status estimates in heart failure with preserved ejection fraction: insights from TOPCAT.
Grodin JL, Philips S, Mullens W, Nijst P, Martens P, Fang JC, Drazner MH, Tang WHW, Pandey A European journal of heart failure 2019 Feb
Prognostic Implications of Changes in Amino-Terminal Pro-B-Type Natriuretic Peptide in Acute Decompensated Heart Failure: Insights from ASCEND-HF.
Grodin JL, Liebo MJ, Butler J, Metra M, Felker GM, Hernandez AF, Voors AA, McMurray JJ, Armstrong PW, O'Connor C, Starling RC, Troughton RW, Wilson Tang WH, Journal of cardiac failure 2019 Apr
Direct comparison of ultrafiltration to pharmacological decongestion in heart failure: a per-protocol analysis of CARRESS-HF.
Grodin JL, Carter S, Bart BA, Goldsmith SR, Drazner MH, Tang WHW European journal of heart failure 2018 Mar
Perturbations in serum chloride homeostasis in heart failure with preserved ejection fraction: insights from TOPCAT.
Grodin JL, Testani JM, Pandey A, Sambandam K, Drazner MH, Fang JC, Tang WHW European journal of heart failure 2018 Jun
Clinical Significance of Early Fluid and Weight Change During Acute Heart Failure Hospitalization.
Groarke JD, Stevens SR, Mentz RJ, Cooper LB, Vader JM, AbouEzzeddine OF, Grodin JL, Joyce E, Anstrom KJ, Felker GM, Redfield MM, Stevenson LW, Lala A Journal of cardiac failure 2018 Jan
Implications of Alternative Hepatorenal Prognostic Scoring Systems in Acute Heart Failure (from DOSE-AHF and ROSE-AHF).
Grodin JL, Gallup D, Anstrom KJ, Felker GM, Chen HH, Tang WHW The American journal of cardiology 2017 Mar
Meta-Analysis of Soluble Suppression of Tumorigenicity-2 and Prognosis in Acute Heart Failure.
Aimo A, Vergaro G, Ripoli A, Bayes-Genis A, Pascual Figal DA, de Boer RA, Lassus J, Mebazaa A, Gayat E, Breidthardt T, Sabti Z, Mueller C, Brunner-La Rocca HP, Tang WH, Grodin JL, Zhang Y, Bettencourt P, Maisel AS, Passino C, Januzzi JL, Emdin M JACC. Heart failure 2017 Feb
Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial.
Kitai T, Grodin JL, Mentz RJ, Hernandez AF, Butler J, Metra M, McMurray JJ, Armstrong PW, Starling RC, O'Connor CM, Swedberg K, Tang WH European journal of heart failure 2016 Sep
Implications of Serum Chloride Homeostasis in Acute Heart Failure (from ROSE-AHF).
Grodin JL, Sun JL, Anstrom KJ, Chen HH, Starling RC, Testani JM, Tang WH The American journal of cardiology 2016 Sep
Prognostic implication of relative regional strain ratio in cardiac amyloidosis.
Senapati A, Sperry BW, Grodin JL, Kusunose K, Thavendiranathan P, Jaber W, Collier P, Hanna M, Popovic ZB, Phelan D Heart (British Cardiac Society) 2016 May 102 10 748-54
Prevalence, Profile, and Prognosis of Severe Obesity in Contemporary Hospitalized Heart Failure Trial Populations.
Joyce E, Lala A, Stevens SR, Cooper LB, AbouEzzeddine OF, Groarke JD, Grodin JL, Braunwald E, Anstrom KJ, Redfield MM, Stevenson LW JACC. Heart failure 2016 Dec 4 12 923-931
Hypochloremia and Diuretic Resistance in Heart Failure: Mechanistic Insights.
Hanberg JS, Rao V, Ter Maaten JM, Laur O, Brisco MA, Perry Wilson F, Grodin JL, Assefa M, Samuel Broughton J, Planavsky NJ, Ahmad T, Bellumkonda L, Tang WH, Parikh CR, Testani JM Circulation. Heart failure 2016 Aug 9 8
Timing and Causes of Readmission After Acute Heart Failure Hospitalization-Insights From the Heart Failure Network Trials.
Vader JM, LaRue SJ, Stevens SR, Mentz RJ, DeVore AD, Lala A, Groarke JD, AbouEzzeddine OF, Dunlay SM, Grodin JL, Dávila-Román VG, de Las Fuentes L Journal of cardiac failure 2016 Apr
Prognostic value of estimating functional capacity with the use of the duke activity status index in stable patients with chronic heart failure.
Grodin JL, Hammadah M, Fan Y, Hazen SL, Tang WH Journal of cardiac failure 2015 Jan 21 1 44-50
Treatment strategies for the prevention of heart failure.
Grodin JL, Tang WH Current heart failure reports 2013 Dec 10 4 331-40
Respiratory syncytial virus pneumonia treated with lower-dose palivizumab in a heart transplant recipient.
Grodin JL, Wu KS, Kitchell EE, Le J, Mishkin JD, Drazner MH, Markham DW Case reports in cardiology 2012 2012 723407
Predictors of Death in Adults With Duchenne Muscular Dystrophy-Associated Cardiomyopathy.
Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA Journal of the American Heart Association 2017 Oct 6 10
Body Mass Index, Natriuretic Peptides, and Risk of Adverse Outcomes in Patients With Heart Failure and Preserved Ejection Fraction: Analysis From the TOPCAT Trial.
Pandey A, Berry JD, Drazner MH, Fang JC, Tang WHW, Grodin JL Journal of the American Heart Association 2018 Nov 7 21 e009664
Reply: Hypochloremia in Acute Decompensated Heart Failure.
Grodin JL, Testani JM, Tang WH Journal of the American College of Cardiology 2015 Dec 66 23 2683-4
Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure.
Tang WH, Wu Y, Grodin JL, Hsu AP, Hernandez AF, Butler J, Metra M, Voors AA, Felker GM, Troughton RW, Mills RM, McMurray JJ, Armstrong PW, O'Connor CM, Starling RC JACC. Heart failure 2016 Jan 4 1 68-77
Trends and causes of hospitalizations in patients with amyloidosis.
Patil N, Arora S, Qamar A, Strassle PD, Alexander KM, Fatima A, Maurer MS, Grodin JL, Pandey A, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2019 Jun 1-2
Generalizability and Implications of the H2FPEF Score in a Cohort of Patients With Heart Failure With Preserved Ejection Fraction.
Segar MW, Patel KV, Berry JD, Grodin JL, Pandey A, Circulation 2019 Apr 139 15 1851-1853
Delayed febrile response with bloodstream infections in patients with continuous-flow left ventricular assist devices.
Wrobel CA, Drazner MH, Ayers CR, Pham DD, La Hoz RM, Grodin JL, Garg S, Mammen PPA, Morlend RM, Araj F, Amin AA, Cornwell WK, Thibodeau JT Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2019 Mar 67 3 653-658
Hemodynamic factors associated with serum chloride in ambulatory patients with advanced heart failure.
Grodin JL, Mullens W, Dupont M, Taylor DO, McKie PM, Starling RC, Testani JM, Tang WHW International journal of cardiology 2018 Feb 252 112-116
Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights from the ASCEND-HF Trial.
Grodin JL, Butler J, Metra M, Felker GM, Voors AA, McMurray JJ, Armstrong PW, Hernandez AF, O'Connor C, Starling RC, Wilson Tang WH Journal of cardiac failure 2018 Jul
Determinants of Diuretic Responsiveness and Associated Outcomes during Acute Heart Failure Hospitalization: an Analysis From the NHLBI Heart Failure Network Clinical Trials.
Kiernan MS, Stevens SR, Tang WHW, Butler J, Anstrom KJ, Birati EY, Grodin JL, Gupta D, Margulies KB, LaRue S, Dávila-Román VG, Hernandez AF, de Las Fuentes L Journal of cardiac failure 2018 Feb
Diuretic Strategies in Acute Decompensated Heart Failure.
Hardin EA, Grodin JL Current heart failure reports 2017 Feb
Circulating levels of matrix metalloproteinase-9 and abdominal aortic pathology: from the Dallas Heart Study.
Grodin JL, Powell-Wiley TM, Ayers CR, Kumar DS, Rohatgi A, Khera A, McGuire DK, de Lemos JA, Das SR Vascular medicine (London, England) 2011 Oct 16 5 339-45
Temporal association between hospitalization event and subsequent risk of mortality among patients with stable chronic heart failure with preserved ejection fraction: insights from the TOPCAT trial.
Pandey A, Patel KV, Ayers C, Tang WHW, Fang JC, Drazner MH, Berry J, Grodin JL, European journal of heart failure 2019 Apr
Intensive Blood Pressure Control and Body Size.
Hendren NS, Neeland IJ, Vongpatanasin W, Kumbhani DJ, Drazner MH, Tang WHW, Grodin JL Journal of the American College of Cardiology 2018 Sep 72 11 1317-1318
I will take my heart failure 'lactate-free' please.
Grodin JL, Tang WHW European journal of heart failure 2018 Apr
Finding Mentorship Among Your Peers: Sharing the Wealth.
Sperry BW, Grodin JL Journal of the American College of Cardiology 2016 Dec 68 23 2585-2587
Hemodynamically, the kidney is at the heart of cardiorenal syndrome.
Grodin JL Cleveland Clinic journal of medicine 2018 Mar 85 3 240-242
Novel Biomarkers of Heart Failure: Do They Have Incremental Clinical Utility?
Tang WH, Grodin JL Journal of cardiac failure 2016 Apr 22 4 263-4
- Variation of heart transplant rates in the united states during holidays.
- Heart Failure Epidemiology
- Chronic Heart Failure
- Cardiorenal Physiology
- Cardiac Transplantation and Ventricular Assist Devices
- Advanced Heart Failure
- Acute Heart Failure
- Heart Transplant Medicine
- Heart Failure & Cardiac Support
Q&A by Dr. Grodin
Articles by Dr. Grodin
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