- American Association of Neurological Surgeons
- Congress of Neurological Surgeons
- North American Skull Base Society
- Society for Neuro-Oncology
- Texas Association of Neurological Surgeons
Matthew Sun, M.D.
- Neurological Surgery
- Meningiomas
- Skull Base Tumors
New Patient Appointment Accepting Virtual Visits or 214-645-2300
Biography
Matthew Sun, M.D., is an Assistant Professor in the Department of Neurological Surgery at UT Southwestern Medical Center. He specializes in the treatment of meningiomas, skull base tumors including pituitary tumors, gliomas, brain metastases, and other brain tumors. He offers treatment through all modalities, including conventional open cranial surgery, endoscopic minimally invasive surgery, and radiosurgery.
Dr. Sun earned his medical degree at the University of California, San Francisco. He completed a residency in neurological surgery at the Ronald Reagan UCLA Medical Center and gained advanced training through a combined cerebrovascular and skull base fellowship at the University of Miami’s Jackson Memorial Hospital.
He joined the UT Southwestern faculty in 2023.
Dr. Sun’s research (Sun Lab) focuses on developing novel immunotherapies for meningiomas. He wants to understand the immune microenvironment of malignant meningiomas and develop targeted immunotherapy regimens incorporating adoptive T cell therapy. His goal is to develop a brain tumor immunotherapy program and conduct clinical trials to test new immunotherapies for meningiomas.
His research has been supported by various grants and ongoing support through the UT Southwestern Clinical Scholars Program. He has authored more than 50 publications on neurosurgery, delivered podium presentations at national neuro-oncology and neurosurgery conferences, and contributed to the textbook Youmans and Winn Neurological Surgery.
His research on meningioma immunotherapy won the Best Basic Science Research Award at the 2021 Western Neurosurgical Society Meeting, as well as the Synaptic Preuss Brain Tumor Research Award at the 2022 American Association of Neurological Surgeons Meeting.
Personal Note
When he’s not at work, Dr. Sun enjoys traveling, playing simulated racing, watching Formula 1, playing the violin, going to the gym, and hiking.
Education & Training
- Residency - University of California Los Angeles (2015-2022)
- Fellowship - University of Miami (2022-2023), Combined Cerebrovascular and Skullbase
- Medical School - University of California (San Francisco)
Professional Associations & Affiliations
Honors & Awards
- Synaptic Preuss Research Award 2022, American Association of Neurological Surgeons Meeting
- Best Basic Science Research Award 2021, Western Neurosurgical Society Meeting
- Silver Award, Resident Research Symposium 2020, University of California, Los Angeles
- Resident Award for Academic Excellence 2019, University of California, Los Angeles, Neurosurgery Department
Books & Publications
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Books
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Brain tumor immunology and immunotherapy in Youmans and Winn Neurological Surgery (8th ed.)
Uy B, Sun MZ, Everson RG, Liau LM (2022), Elsevier
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Brain tumor immunology and immunotherapy in Youmans and Winn Neurological Surgery (8th ed.)
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Publications
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The social deprivation index and perioperative outcomes following meningioma resection.
Ebada A, Shukla IY, Bever N, Sun MZ, Clinical neurology and neurosurgery 2026 Mar 262 109307 -
Tumor control following gamma knife radiosurgery for parasagittal meningiomas: a single institution retrospective analysis.
Ebada A, Bever N, Shukla IY, Traylor JI, Wan B, Timmerman RD, Dohopolski M, De Vis J, Patel T, Patel A, Barnett SL, Wardak Z, Dan T, Sun MZ, Clinical neurology and neurosurgery 2025 Oct 259 109219 -
Comparative Outcomes of Standard Radiation Therapy and 5-Fraction Adaptive Stereotactic Radiation Therapy in Newly Diagnosed Glioblastoma: A Propensity Score-Matched Analysis.
Dohopolski M, Schmitt LG, de Vis J, Mostardeiro TR, Anand S, Youssef M, Noch E, Maher E, Sun M, Patel T, Patel A, Barnett S, Lee M, Iakovenko V, Chiu T, Su FC, Pompos A, Lin MH, Cai X, Timmerman R, Dan T, Wardak Z, Advances in radiation oncology 2025 Aug 10 8 101813 -
Immunotherapeutic targeting of NY-ESO-1 in malignant meningiomas with TCR-transduced T-cells.
Sun MZ, Contreras E, Treger J, Imbroane M, Orpilla J, Ko M, Reynoso J, Khattab S, Lai TJ, Tsang JE, Vitte J, Giovannini M, Liau LM, Prins R, Everson RG, Journal of neuro-oncology 2025 Aug -
Disparities in meningioma resection outcomes: a retrospective analysis of patients with public versus private insurance.
Bever N, Shukla IY, Ebada A, Wan B, Shah D, Traylor JI, Barnett SL, Sun MZ, Journal of neuro-oncology 2025 Jul -
Online and ChatGPT-generated patient education materials regarding brain tumor prognosis fail to meet readability standards.
Shukla IY, Sun MZ, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 Jun 138 111410 -
Prognostic value of MIB-1 index in meningioma: a retrospective cohort study to establish an optimal cutoff for recurrence and survival.
Shukla IY, Ebada A, Bever N, Traylor JI, Wan B, Shah D, Barnett SL, Sun MZ, Journal of neuro-oncology 2025 May -
Epigenetic induction of cancer testis antigens and endogenous retroviruses at single-cell level enhances immune recognition and response in glioma.
Lai TJ, Sun L, Li K, Prins TJ, Treger J, Li T, Sun MZ, Nathanson DA, Liau LM, Lai A, Prins RM, Everson RG, Cancer research communications 2024 Jun -
Neuroanatomy guidance to successful neurosurgical interventions.
Sun MZ, Morcos JJ Surgical anatomy of the cavernous sinus and refinement of its surgery 2024 1 397- 411 -
Approaches to the Middle Cerebellar Peduncle for Resection of Pontine Cavernomas.
Wu EM, Khan NR, Sun MZ, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Nov -
Clipping of Recurrent Right Middle Cerebral Artery Trifurcation Aneurysm With Extracranial-Intracranial and Intracranial-Intracranial Bypass Using a Radial Artery Graft: 2-Dimensional Operative Video.
Sun MZ, Wu EM, Starke RM, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Oct -
"Stump Patch Rescue" Reclipping Using Divided Origin of Temporal M2 in a Recurrent Reruptured Bilobed Middle Cerebral Artery Bifurcation Aneurysm: 2-Dimensional Operative Video.
Wu EM, Sun MZ, Starke RM, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Sep 25 3 e163 -
Combined Transcavernous and Anterior Petrosectomy [Kawase] Approach to a Trigeminal Schwannoma: 2-Dimensional Operative Video.
Wu EM, Sun MZ, Khan NR, Benjamin CG, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Sep 25 3 e150 -
Hakuba-Dolenc Approach for Resection of a Large Cavernous Sinus Dermoid Cyst: 2-Dimensional Operative Video.
Sun MZ, Wu EM, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Aug 25 2 e88 -
Kawase Approach for "Macrovascular" Decompression of Dolichoectatic Basilar Artery Causing Hemifacial Spasm Using Gore-tex Sling: 2-Dimensional Operative Video.
Wu EM, Sun MZ, Khan NR, Morcos JJ, Operative neurosurgery (Hagerstown, Md.) 2023 Aug 25 2 e84 -
Contralateral transfalcine approach for resection of right medial frontal AVM.
Sun MZ, Wu EM, Costello MC, Abdelsalam A, Starke RM, Morcos JJ, Clinical neurology and neurosurgery 2023 Jun 232 107843 -
Upper lumbar spine far lateral disc herniations masquerading as peripheral nerve sheath tumors: illustrative cases.
Uy BR, Sun MZ, Muftuoglu Y, Cheng M, Kim WJ, Magaki S, Yoo BY, Salehi B, Beckett JS, Macyszyn L, Journal of neurosurgery. Case lessons 2023 Apr 5 14 -
Machine learning predicts improvement of functional outcomes in traumatic brain injury patients after inpatient rehabilitation.
Say I, Chen YE, Sun MZ, Li JJ, Lu DC, Frontiers in rehabilitation sciences 2022 3 1005168 -
Youmans and winn neurological surgery.
UY B, Sun MZ, Everson RG, Liau LM Brain Tumor Immunology and Immunotherapy. 2022 2 913 -922 -
Venous thromboembolic (VTE) prophylaxis in cushing disease patients undergoing transsphenoidal surgery.
McCormick JP, Sun M, Shafqat I, Heaney AP, Bergsneider M, Wang MB Interdisciplinary neurosurgery: advanced techniques and case management 2022 27 -
Relationship Between Superior Semicircular Canal Dehiscence Volume with Clinical Symptoms: Case Series.
Preet K, Udawatta M, Mozaffari K, Ong V, Franks A, Ng E, Gaonkar B, Sun MZ, Salamon N, Gopen Q, Yang I, World neurosurgery 2021 Dec 156 e345-e350 -
Selective scalp block decreases short term post-operative pain scores and opioid use after craniotomy: A case series.
Patel KS, Sun MZ, Willis SL, Alemnew M, De Jong R, Evans AS, Duong C, Gopen Q, Yang I, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021 Nov 93 183-187 -
Predictors of mortality and tumor recurrence in desmoplastic infantile ganglioglioma and astrocytoma-and individual participant data meta-analysis (IPDMA).
Wang S, Sun MZ, Abecassis IJ, Weil AG, Ibrahim GM, Fallah A, Ene C, Leary SES, Cole BL, Lockwood CM, Olson JM, Geyer JR, Ellenbogen RG, Ojemann JG, Wang AC, Journal of neuro-oncology 2021 Nov 155 2 155-163 -
Superior Semicircular Canal Dehiscence Revision Surgery Outcomes: A Single Institution's Experience.
Mozaffari K, Ghodrati F, Pradhan A, Ng E, Ding K, Rana S, Duong C, Anderson RN, Enomoto A, Sheppard JP, Sun MZ, Phillips HW, Gopen Q, Yang I, World neurosurgery 2021 Sep -
Postoperative Admission of Adult Craniotomy Patients to the Neuroscience Ward Reduces Length of Stay and Cost.
Sun MZ, Babayan D, Chen JS, Wang MM, Naik PK, Reitz K, Li JJ, Pouratian N, Kim W, Neurosurgery 2021 Apr -
Impact of 3-d virtual reality visualization on patient education, engagement, and satisfaction in pre-surgical consultation.
Sun MZ, Peeters SM, Wang AC Journal of surgery and research 2021 4 4 711-722 -
Spontaneous Resolution of Dural and Pial Arteriovenous Fistulae Arising After Superficial Temporal Artery to Middle Cerebral Artery Bypass for Moyamoya Disease.
Peeters SM, Colby GP, Guivatchian E, Sun MZ, Tateshima S, Wang AC, World neurosurgery 2020 Oct 142 404-407 -
Thinning or dehiscence of bone in structures of the middle cranial fossa floor in superior semicircular canal dehiscence.
Arsenault JJ, Romiyo P, Miao T, Monteiro K, De Jong R, Kaur T, Johanis M, Duong C, Sheppard JP, Sun MZ, Ferraro R, Salamon N, Yang I, Gopen Q, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2020 Apr 74 104-108 -
A systematic analysis of stereotactic radiosurgery surveys for residents in neurosurgery training programs.
Ding K, Romiyo P, Ng E, Udawatta M, Dejam D, Phillips HW, Sun MZ, Yang I, Journal of the neurological sciences 2020 Apr 116867 -
In Reply: Systemic Antimicrobial Prophylaxis and Antimicrobial-Coated External Ventricular Drain Catheters for Preventing Ventriculostomy-Related Infections: A Meta-Analysis of 5242 Cases.
Sheppard JP, Duong C, Lagman C, Patel K, Sun MZ, Prashant GN, Yang I, Neurosurgery 2020 Feb 86 2 E240-E243 -
Meta-analysis of tumor control rates in patients undergoing stereotactic radiosurgery for cystic vestibular schwannomas.
Ding K, Ng E, Romiyo P, Dejam D, Udawatta M, Sun MZ, Gopen Q, Yang I, Clinical neurology and neurosurgery 2019 Oct 188 105571 -
Patient safety analysis in radiation burden of head computed tomography imaging in 1,185 neurosurgical inpatients.
Sheppard JP, Duong C, Romiyo P, Azzam D, Alkhalid Y, Nguyen T, Babayan D, Lagman C, Sun MZ, Prashant GN, Beckett JS, Yang I, World neurosurgery 2019 Sep -
CT evaluation of normal bone thickness overlying the superior semicircular canal.
Kaur T, Johanis M, Miao T, Romiyo P, Duong C, Sun MZ, Ferraro R, Salamon N, McArthur D, Yang I, Gopen Q, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2019 Aug 66 128-132 -
Survival impact of time to initiation of chemoradiotherapy after resection of newly diagnosed glioblastoma.
Sun MZ, Oh T, Ivan ME, Clark AJ, Safaee M, Sayegh ET, Kaur G, Parsa AT, Bloch O, Journal of neurosurgery 2015 May 122 5 1144-50 -
Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas.
Ivan ME, Safaee M, Oh T, Clark AJ, Sun MZ, Kim J, Bloch O, Jahangiri A, Phillips JJ, Aghi MK, Parsa AT, Journal of neuro-oncology 2015 Jan 121 1 53-61 -
Proportional upregulation of CD97 isoforms in glioblastoma and glioblastoma-derived brain tumor initiating cells.
Safaee M, Fakurnejad S, Bloch O, Clark AJ, Ivan ME, Sun MZ, Oh T, Phillips JJ, Parsa AT, PloS one 2015 10 2 e0111532 -
Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma.
Sun MZ, Ivan ME, Oh MC, Delance AR, Clark AJ, Safaee M, Oh T, Kaur G, Molinaro A, Gupta N, Parsa AT, Journal of neuro-oncology 2014 Nov 120 2 353-60 -
Surgical risk factors for post-operative pneumonia following meningioma resection.
Oh T, Safaee M, Sun MZ, Garcia RM, McDermott MW, Parsa AT, Bloch O, Clinical neurology and neurosurgery 2014 Mar 118 76-9
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The social deprivation index and perioperative outcomes following meningioma resection.
Research
- Meningiomas
- Brain tumor immunotherapy
- Adoptive T cell therapy
Clinical Focus
- Meningiomas
- Skull Base Tumors
- Pituitary Tumors
- Brain Metastases
- Gliomas and Other Brain Tumors
Links
Neuro-Oncology Clinic
at Cancer Care Outpatient Building 6202 Harry Hines Blvd., 7th FloorDallas, Texas 75235 (214) 645-4673 Directions to Neuro-Oncology Clinic at Cancer Care Outpatient Building, Dallas Parking Info for Neuro-Oncology Clinic
New Patient Appointment Accepting Virtual Visits or 214-645-2300