- Internship - Children's Health Dallas (1994-1995), Pediatrics
- Medical School - UT Southwestern Medical School (1990-1994)
- Residency - Children's Health Dallas (1995-1997), Pediatrics
- Fellowship - UT Southwestern Medical Center (1997-2000), Neonatal-perinatal Medicine
Myra Wyckoff, M.D.
- Pediatrics - Neonatal-Perinatal
Dr. Wyckoff earned her engineering science degree from Trinity University in San Antonio, TX. She then came to UTSW Medical Center at Dallas for medical school and subsequently stayed for General Pediatrics training. She remained at UTSW for Neonatal-Perinatal Medicine training and worked under Phil Shaul, MD on a project which elucidated how plasma membrane estrogen receptors are coupled to eNOS production via G-protein signaling. Upon completion of sub-specialty training she joined the faculty of UTSW Pediatrics Department to become the director of Newborn Resuscitation Services at Parkland Memorial Hospital, a large, urban county hospital with over 12,000 deliveries annually. She developed and coordinates an educational rotation in newborn resuscitation for the senior pediatric house-officer, 2nd year emergency medicine residents, neonatal-perinatal medicine fellows and OB anesthesia fellows. In addition, she oversees the continued development of the high-risk neonatal resuscitation team. Dr. Wyckoff maintains and utilizes one of the most comprehensive neonatal resuscitation databases in the country to continually try to improve neonatal resuscitation processes locally and nationally. Prospective resuscitation protocols are studied in the delivery room and she has developed a neonatal piglet model of asphyxia-induced hypotension/bradycardia and asphyxia-induced asystole to better elucidate the hemodynamics and optimize resuscitation strategies during CPR in the controlled setting of the laboratory. She has served on the International Liaison Committee on Resuscitation, Newborn Subsection since 2003 and currently co-chair of the Neonatal Task Force. She has served on the American Academy of Pediatrics Neonatal Resuscitation Program Steering Committee since 2006 and recently completed 2 terms Co-chair. Since 2013 she has served as UTSW site PI for the NICHD Neonatal Research Network.
- Texas Medical Association
- Dallas County Medical Society
- American Academy of Pediatrics (2000)
- American Heart Association (2006)
- Society for Pediatric Research (2007)
- Perinatal Research Society (2008)
- Pediatric Faculty Teaching Award, UT Southwestern Pediatric Program Residents (2006, 2008, 2011)
- AOA 1994, Medical Academic Honor Society
- Elected to Society for Pediatric Research 2006
- Acute Care Rotation Teaching Award 2007-2009, UT Southwestern Medical School
- Invited Lectureship, 6th Annual Fellows' Invited Lectureship 2014, Wayne State University, Detroit, MI
- Elected to Perinatal Research Society 2008
- Elected Co-Chair of the Neonatal Resuscitation Program Steering Committee 2011, American Academy of Pediatrics
Delivery Room Resuscitation in Rudolph CD, Rudolph AM, Lister G, First LR, Gershon AA, eds. Rudolph's Pediatrics. 22nd ed.
Wyckoff MH. (2011), McGraw-Hill; 164-169.
Chest Compression, Medications, and Special Problems in Neonatal Resuscitation in Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine. 2nd ed.
Wyckoff M, Goldsmith JP. (2014), Elsevier Saunders.
Medications in NRP Neonatal Resuscitation Textbook. 6th ed.
Wyckoff MH. (2011), American Academy of Pediatrics/American Heart Association; 211-236.
Respiratory and Cardiovascular Support in the Delivery Room in Bancalari E, ed. The Newborn Lung: Neonatology Questions and Controversies. 2nd ed.
Wyckoff MH. (2012), Philadelphia: Elsevier Saunders; 247-264.
- Delivery Room Resuscitation in Rudolph CD, Rudolph AM, Lister G, First LR, Gershon AA, eds. Rudolph's Pediatrics. 22nd ed.
Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.
Sarkar S, Shankaran S, Barks J, Do BT, Laptook AR, Das A, Ambalavanan N, Van Meurs KP, Bell EF, Sanchez PJ, Hintz SR, Wyckoff MH, Stoll BJ, Carlo WA The Journal of pediatrics 2018 Feb
The International Liaison Committee for Resuscitation-Review of the last 25 years and vision for the future.
Perkins GD, Neumar R, Monsieurs KG, Lim SH, Castren M, Nolan JP, Nadkarni V, Montgomery B, Steen P, Cummins R, Chamberlain D, Aickin R, de Caen A, Wang TL, Stanton D, Escalante R, Callaway CW, Soar J, Olasveengen T, Maconochie I, Wyckoff M, Greif R, Singletary EM, O'Connor R, Iwami T, Morrison L, Morley P, Lang E, Bossaert L Resuscitation 2017 Oct
Outcomes of Extremely Preterm Infants Born to Insulin-Dependent Diabetic Mothers.
Boghossian NS, Hansen NI, Bell EF, Brumbaugh JE, Stoll BJ, Laptook AR, Shankaran S, Wyckoff MH, Colaizy TT, Das A, Higgins RD Pediatrics 2016 May
Endotracheal delivery of medications during neonatal resuscitation.
Wyckoff MH, Wyllie J Clinics in perinatology 2006 Mar 33 1 153-60, ix
Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012.
Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sánchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD JAMA 2015 Sep 314 10 1039-51
Epinephrine Use during Newborn Resuscitation.
Kapadia VS, Wyckoff MH Frontiers in pediatrics 2017 5 97
Neonatal cardiopulmonary resuscitation: Critical hemodynamics
Wyckoff MH NeoReviews 2010 March 11 3 e123-e129
Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants.
Laptook AR, Bell EF, Shankaran S, Boghossian NS, Wyckoff MH, Kandefer S, Walsh M, Saha S, Higgins R The Journal of pediatrics 2018 Jan 192 53-59.e2
Efficacy of pharmacologic closure of patent ductus arteriosus in small-for-gestational-age extremely preterm infants.
Boghossian NS, Do BT, Bell EF, Dagle JM, Brumbaugh JE, Stoll BJ, Vohr BR, Das A, Shankaran S, Sanchez PJ, Wyckoff MH, Bethany Ball M Early human development 2017 Jul 113 10-17
Impact of the Neonatal Resuscitation Program-Recommended Low Oxygen Strategy on Outcomes of Infants Born Preterm.
Kapadia VS, Lal CV, Kakkilaya V, Heyne R, Savani RC, Wyckoff MH The Journal of pediatrics 2017 Dec 191 35-41
Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, Parikh NA, Ambalavanan N, Pedroza C, Pappas A, Das A, Chaudhary AS, Ehrenkranz RA, Hensman AM, Van Meurs KP, Chalak LF, Hamrick SEG, Sokol GM, Walsh MC, Poindexter BB, Faix RG, Watterberg KL, Frantz ID, Guillet R, Devaskar U, Truog WE, Chock VY, Wyckoff MH, McGowan EC, Carlton DP, Harmon HM, Brumbaugh JE, Cotten CM, Sánchez PJ, Hibbs AM, Higgins RD JAMA 2017 10 318 16 1550-1560
The impact of ambient operating room temperature on neonatal and maternal hypothermia and associated morbidities: a randomized controlled trial.
Duryea EL, Nelson DB, Wyckoff MH, Grant EN, Tao W, Sadana N, Chalak LF, McIntire DD, Leveno KJ American journal of obstetrics and gynecology 2016 Feb
Perinatal Asphyxia with Hyperoxemia within the First Hour of Life Is Associated with Moderate to Severe Hypoxic-Ischemic Encephalopathy.
Kapadia VS, Chalak LF, Dupont TL, Rollins NK, Brion LP, Wyckoff MH The Journal of pediatrics 2013 Jun
Resuscitation of preterm neonates with limited versus high oxygen strategy.
Kapadia VS, Chalak LF, Sparks JE, Allen JR, Savani RC, Wyckoff MH Pediatrics 2013 Dec 132 6 e1488-96
Chest compressions for bradycardia or asystole in neonates.
Kapadia V, Wyckoff MH Clinics in perinatology 2012 Dec 39 4 833-42
Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100% oxygen.
Østerholt HC, Dannevig I, Wyckoff MH, Liao J, Akgul Y, Ramgopal M, Mija DS, Cheong N, Longoria C, Mahendroo M, Nakstad B, Saugstad OD, Savani RC PloS one 2012 7 6 e38839
End-tidal CO2 detection of an audible heart rate during neonatal cardiopulmonary resuscitation after asystole in asphyxiated piglets.
Chalak LF, Barber CA, Hynan L, Garcia D, Christie L, Wyckoff MH Pediatric research 2011 May 69 5 Pt 1 401-5
Extended series of cardiac compressions during CPR in a swine model of perinatal asphyxia.
Solevåg AL, Dannevig I, Wyckoff M, Saugstad OD, Nakstad B Resuscitation 2010 Nov 81 11 1571-6
Enterovirus is not present in placentas from cases of perinatal depression using polymerase chain reaction analysis.
Cover J, Popek E, Wyckoff M, Leos NK, Rogers BB Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2009 May-Jun 12 3 177-9
Optimizing chest compressions during delivery-room resuscitation.
Wyckoff MH, Berg RA Seminars in fetal & neonatal medicine 2008 Dec 13 6 410-5
Use of high-dose epinephrine and sodium bicarbonate during neonatal resuscitation: is there proven benefit?
Wyckoff MH, Perlman JM Clinics in perinatology 2006 Mar 33 1 141-51, viii-ix
Gastric suction at birth.
Conklin LS, Perlman JM, Wyckoff MH The Journal of pediatrics 2005 Jan 146 1 152-3; author reply 153
Neonatal lethal osteochondrodysplasia with low serum levels of alkaline phosphatase and osteocalcin.
Wyckoff MH, El-Turk C, Laptook A, Timmons C, Gannon FH, Zhang X, Mumm S, Whyte MP The Journal of clinical endocrinology and metabolism 2005 Feb 90 2 1233-40
Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants.
Natarajan G, Shankaran S, Saha S, Laptook A, Das A, Higgins R, Stoll BJ, Bell EF, Carlo WA, D'Angio C, DeMauro SB, Sanchez P, Van Meurs K, Vohr B, Newman N, Hale E, Walsh M The Journal of pediatrics 2018 Jan
Perinatal management: What has been learned through the network?
Chawla S, Foglia EE, Kapadia V, Wyckoff MH Seminars in perinatology 2016 Aug
Change in Care Among Nonenrolled Patients During and After a Randomized Trial.
Levan JM, Wyckoff MH, Ahn C, Heyne R, Sánchez PJ, Chalak L, Jaleel MA, Burchfield PJ, Christie L, Soll R, Badger GJ, Brion LP Pediatrics 2013 Sep
The two-thumb is superior to the two-finger method for administering chest compressions in a manikin model of neonatal resuscitation.
Christman C, Hemway RJ, Wyckoff MH, Perlman JM Archives of disease in childhood. Fetal and neonatal edition 2011 Mar 96 2 F99-F101
Part 15: neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Kattwinkel J, Perlman JM, Aziz K, Colby C, Fairchild K, Gallagher J, Hazinski MF, Halamek LP, Kumar P, Little G, McGowan JE, Nightengale B, Ramirez MM, Ringer S, Simon WM, Weiner GM, Wyckoff M, Zaichkin J Circulation 2010 Nov 122 18 Suppl 3 S909-19
Drugs during delivery room resuscitation - What, when and why?
Kapadia VS, Wyckoff MH Seminars in fetal & neonatal medicine 2013 Aug
Use of volume expansion during delivery room resuscitation in near-term and term infants.
Wyckoff MH, Perlman JM, Laptook AR Pediatrics 2005 Apr 115 4 950-5
Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.
Perlman JM, Wyllie J, Kattwinkel J, Atkins DL, Chameides L, Goldsmith JP, Guinsburg R, Hazinski MF, Morley C, Richmond S, Simon WM, Singhal N, Szyld E, Tamura M, Velaphi S Pediatrics 2010 Nov 126 5 e1319-44
Oxygen Therapy in the Delivery Room: What Is the Right Dose?
Kapadia V, Wyckoff MH Clinics in perinatology 2018 Jun 45 2 293-306
Animal models in neonatal resuscitation research: What can they teach us?
Hooper SB, Te Pas AB, Polglase GR, Wyckoff M, Seminars in fetal & neonatal medicine 2018 10 23 5 300-305
Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants.
Watterberg KL, Fernandez E, Walsh MC, Truog WE, Stoll BJ, Sokol GM, Kennedy KA, Fraga MV, Beauman SS, Carper B, Das A, Duncan AF, Buss WF, Gauldin C, Lacy CB, Sanchez PJ, Chawla S, Lakshminrusimha S, Cotten CM, Van Meurs KP, Poindexter BB, Bell EF, Carlo WA, Devaskar U, Wyckoff MH, Higgins RD Journal of perinatology : official journal of the California Perinatal Association 2017 Sep
Identification of Extremely Premature Infants at Low Risk for Early-Onset Sepsis.
Puopolo KM, Mukhopadhyay S, Hansen NI, Cotten CM, Stoll BJ, Sanchez PJ, Bell EF, Das A, Hensman AM, Van Meurs KP, Wyckoff MH Pediatrics 2017 Oct
Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest.
Vali P, Chandrasekharan P, Rawat M, Gugino S, Koenigsknecht C, Helman J, Jusko WJ, Mathew B, Berkelhamer S, Nair J, Wyckoff MH, Lakshminrusimha S Journal of the American Heart Association 2017 Feb 6 2
Hemodynamics and gas exchange during chest compressions in neonatal resuscitation.
Vali P, Chandrasekharan P, Rawat M, Gugino S, Koenigsknecht C, Helman J, Mathew B, Berkelhamer S, Nair J, Wyckoff M, Lakshminrusimha S PloS one 2017 12 4 e0176478
Part 7: Neonatal Resuscitation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.
Perlman JM, Wyllie J, Kattwinkel J, Wyckoff MH, Aziz K, Guinsburg R, Kim HS, Liley HG, Mildenhall L, Simon WM, Szyld E, Tamura M, Velaphi S Circulation 2015 Oct 132 16 Suppl 1 S204-41
Change in practice after the Surfactant, Positive Pressure and Oxygenation Randomised Trial.
LeVan JM, Brion LP, Wrage LA, Gantz MG, Wyckoff MH, Sánchez PJ, Heyne R, Jaleel M, Finer NN, Carlo WA, Das A, Stoll BJ, Higgins RD Archives of disease in childhood. Fetal and neonatal edition 2014 May
Outcome of extremely low birth weight infants who received delivery room cardiopulmonary resuscitation.
Wyckoff MH, Salhab WA, Heyne RJ, Kendrick DE, Stoll BJ, Laptook AR The Journal of pediatrics 2012 Feb 160 2 239-244.e2
Return of spontaneous circulation with a compression:ventilation ratio of 15:2 versus 3:1 in newborn pigs with cardiac arrest due to asphyxia.
Solevåg AL, Dannevig I, Wyckoff M, Saugstad OD, Nakstad B Archives of disease in childhood. Fetal and neonatal edition 2011 Nov 96 6 F417-21
Randomized trial of volume infusion during resuscitation of asphyxiated neonatal piglets.
Wyckoff M, Garcia D, Margraf L, Perlman J, Laptook A Pediatric research 2007 Apr 61 4 415-20
Naloxone during neonatal resuscitation: acknowledging the unknown.
Guinsburg R, Wyckoff MH Clinics in perinatology 2006 Mar 33 1 121-32, viii
Neonatal resuscitation guidelines versus the reality of the delivery room.
Wyckoff MH The Journal of pediatrics 2013 Dec 163 6 1542-3
Efficacy of Intravenous and Endotracheal Epinephrine during Neonatal Cardiopulmonary Resuscitation in the Delivery Room.
Halling C, Sparks JE, Christie L, Wyckoff MH The Journal of pediatrics 2017 Mar
Neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Kattwinkel J, Perlman JM, Aziz K, Colby C, Fairchild K, Gallagher J, Hazinski MF, Halamek LP, Kumar P, Little G, McGowan JE, Nightengale B, Ramirez MM, Ringer S, Simon WM, Weiner GM, Wyckoff M, Zaichkin J Pediatrics 2010 Nov 126 5 e1400-13
Part 1: Executive Summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Neumar RW, Shuster M, Callaway CW, Gent LM, Atkins DL, Bhanji F, Brooks SC, de Caen AR, Donnino MW, Ferrer JM, Kleinman ME, Kronick SL, Lavonas EJ, Link MS, Mancini ME, Morrison LJ, O'Connor RE, Samson RA, Schexnayder SM, Singletary EM, Sinz EH, Travers AH, Wyckoff MH, Hazinski MF Circulation 2015 Nov 132 18 Suppl 2 S315-67
Initial resuscitation and stabilization of the periviable neonate: The Golden-Hour approach.
Wyckoff MH Seminars in perinatology 2014 Feb 38 1 12-6
Improving Neonatal Cardiopulmonary Resuscitation Hemodynamics: Are Sustained Inflations During Compressions the Answer?
Wyckoff MH Circulation 2013 Oct
Delayed onset of cardiac compressions in cardiopulmonary resuscitation of newborn pigs with asphyctic cardiac arrest.
Dannevig I, Solevåg AL, Wyckoff M, Saugstad OD, Nakstad B Neonatology 2011 99 2 153-62
Use and efficacy of endotracheal versus intravenous epinephrine during neonatal cardiopulmonary resuscitation in the delivery room.
Barber CA, Wyckoff MH Pediatrics 2006 Sep 118 3 1028-34
Initial Oxygen Concentration for Term Neonatal Resuscitation
Isayama T, Dawson JA, Roehr CC, Rabi Y, Weiner GM, Aziz K, Kapadia VS, de Almeida MF, Trevisanuto D, Mildenhall L, Liley HG, Hosono S, Kim HS, Szyld E, Perlman JM, Velaphi S, Guinsburg R, Welsford M, Nishiyama C, Wyllie JP, Wyckoff MH International Liaison Committee on Resuscitation 2018 Nov
Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants.
Bajaj M, Natarajan G, Shankaran S, Wyckoff M, Laptook AR, Bell EF, Stoll BJ, Carlo WA, Vohr BR, Saha S, Van Meurs KP, Sanchez PJ, D'Angio CT, Higgins RD, Das A, Newman N, Walsh MC The Journal of pediatrics 2018 Jan
Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage.
Pappas A, Adams-Chapman I, Shankaran S, McDonald SA, Stoll BJ, Laptook AR, Carlo WA, Van Meurs KP, Hintz SR, Carlson MD, Brumbaugh JE, Walsh MC, Wyckoff MH, Das A, Higgins RD JAMA pediatrics 2017 Nov
Part 13: Neonatal Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Wyckoff MH, Aziz K, Escobedo MB, Kapadia VS, Kattwinkel J, Perlman JM, Simon WM, Weiner GM, Zaichkin JG Circulation 2015 Nov 132 18 Suppl 2 S543-60
Initial hypoglycemia and neonatal brain injury in term infants with severe fetal acidemia.
Salhab WA, Wyckoff MH, Laptook AR, Perlman JM Pediatrics 2004 Aug 114 2 361-6
Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial.
Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD JAMA 2014 Dec 24-31 312 24 2629-39
Effective ventilation and temperature control are vital to outborn resuscitation.
Wyckoff MH, Perlman JM Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 2004 Apr-Jun 8 2 191-5
- Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.
- Neonatal Research Network
- Neonatal Resuscitation