Trish Perl, M.D.

Chief, Division of Infectious Diseases

Jay P. Sanford Professorship in Infectious Diseases

Internal Medicine - Infectious Diseases and Geographic Medicine
Infectious Disease

New Patient Appointment or 214-645-8300

See Dr. Perl's Locations

Education & Training

Fellowship - University of Iowa Medical Center (1988-1992), Infectious Diseases
Residency - McGill University Faculty of Medicine (1983-1987), Internal Medicine
Medical School - University of North Carolina School of Medicine (1979-1983)

Professional Associations & Affiliations

University of Iowa (1988-1991), Fellow--Infectious Diseases and Clinical Epidemiology
Johns Hopkins University (1996-2016), Assistant Professor to Professor
UTSouthwestern (2016), Professor and Chief of Infectious Diseases

Books & Publications

Publications
- A polymicrobial fungal outbreak in a regional burn center after Hurricane Sandy.
  Sood G, Vaidya D, Dam L, Grubb LM, Zenilman J, Krout K, Khouri-Stevens Z, Bennett R, Blanding R, Riedel S, Milner S, Price LA, Perl TM American journal of infection control 2018 Sep 46 9 1047-1050
- Livestock-Associated, Antibiotic-Resistant Staphylococcus aureus Nasal Carriage and Recent Skin and Soft Tissue Infection among Industrial Hog Operation Workers.
  Nadimpalli M, Stewart JR, Pierce E, Pisanic N, Love DC, Hall D, Larsen J, Carroll KC, Tekle T, Perl TM, Heaney CD PloS one 2016 11 11 e0165713
- Pseudo-outbreak of Penicillium in an outpatient obstetrics and gynecology clinic.
  Sood G, Huber K, Dam L, Riedel S, Grubb L, Zenilman J, Perl TM, Argani C American journal of infection control 2017 May 45 5 557-558
- Healthcare personnel exposure in an emergency department during influenza season.
  Rule AM, Apau O, Ahrenholz SH, Brueck SE, Lindsley WG, de Perio MA, Noti JD, Shaffer RE, Rothman R, Grigorovitch A, Noorbakhsh B, Beezhold DH, Yorio PL, Perl TM, Fisher EM PloS one 2018 13 8 e0203223
- Protecting Healthcare Personnel in Outpatient Settings: The Influence of Mandatory Versus Nonmandatory Influenza Vaccination Policies on Workplace Absenteeism During Multiple Respiratory Virus Seasons.
  Frederick J, Brown AC, Cummings DA, Gaydos CA, Gibert CL, Gorse GJ, Los JG, Nyquist AC, Perl TM, Price CS, Radonovich LJ, Reich NG, Rodriguez-Barradas MC, Bessesen MT, Simberkoff MS Infection control and hospital epidemiology 2018 04 39 4 452-461
- Infections complicating cesarean delivery.
  Sood G, Argani C, Ghanem KG, Perl TM, Sheffield JS Current opinion in infectious diseases 2018 08 31 4 368-376
- Nasal Carriage among Industrial Hog Operation Workers and Household Contacts, USA.
  Nadimpalli ML, Stewart JR, Pierce E, Pisanic N, Love DC, Hall D, Larsen J, Carroll KC, Tekle T, Perl TM, Heaney CD Environmental health perspectives 2018 12 126 12 127005
- Infections: A Snapshot of Processes and Outcomes in the Real World.
  Townsend J, Keller S, Tibuakuu M, Thakker S, Webster B, Siegel M, Psoter KJ, Mansour O, Perl TM Open forum infectious diseases 2018 Nov 5 11 ofy274
- Environmental Exposures and the Risk of Central Venous Catheter Complications and Readmissions in Home Infusion Therapy Patients.
  Keller SC, Williams D, Gavgani M, Hirsch D, Adamovich J, Hohl D, Krosche A, Cosgrove S, Perl TM Infection control and hospital epidemiology 2017 01 38 1 68-75
- National Costs Associated With Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Hospitalizations in the United States, 2010-2014.
  Klein EY, Jiang W, Mojica N, Tseng KK, McNeill R, Cosgrove SE, Perl TM Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Jan 68 1 22-28
- Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008.
  Pfaller MA, Andes DR, Diekema DJ, Horn DL, Reboli AC, Rotstein C, Franks B, Azie NE PloS one 2014 9 7 e101510
- Does use of Electronic Alerts for Systemic Inflammatory Response Syndrome (SIRS) to Identify Patients with Sepsis Improve Mortality?
  Seetharaman S, Wilson C, Landrum M, Qasba S, Katz M, Ladikos N, Harris JE, Galiatsatos P, Yousem DM, Knight AM, Pearse DB, Blanding R, Bennett R, Galai N, Perl TM, Sood G The American journal of medicine 2019 Mar
- Preparedness planning and care of patients under investigation for or with Ebola virus disease: A survey of physicians in North America.
  Lewis JD, Enfield KB, Perl TM, Sifri CD American journal of infection control 2017 Jan 45 1 65-68
- Gonococcal Conjunctivitis: A Case Report of an Unusual Mode of Transmission.
  Bodurtha Smith AJ, Holzman SB, Manesh RS, Perl TM Journal of pediatric and adolescent gynecology 2017 Aug 30 4 501-502
- Practices to Reduce Surgical Site Infections Among Women Undergoing Cesarean Section: A Review.
  McKibben RA, Pitts SI, Suarez-Cuervo C, Perl TM, Bass EB Infection control and hospital epidemiology 2015 Aug 36 8 915-21
- Variable screening and decolonization protocols for Staphylococcus aureus carriage prior to surgical procedures.
  Kline S, Highness M, Herwaldt LA, Perl TM Infection control and hospital epidemiology 2014 Jul 35 7 880-2
- Impact of colonization pressure and strain type on methicillin-resistant Staphylococcus aureus transmission in children.
  Popoola VO, Carroll KC, Ross T, Reich NG, Perl TM, Milstone AM Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Nov 57 10 1458-60
- Risk factors for persistent methicillin-resistant Staphylococcus aureus colonization in children with multiple intensive care unit admissions.
  Popoola VO, Tamma P, Reich NG, Perl TM, Milstone AM Infection control and hospital epidemiology 2013 Jul 34 7 748-50
- Using the Pillars of Infection Prevention to Build an Effective Program for Reducing the Transmission of Emerging and Reemerging Infections.
  Branch-Elliman W, Savor Price C, Bessesen MT, Perl TM Current environmental health reports 2015 Sep 2 3 226-35
- Impact of Toxigenic Clostridium difficile Colonization on the Risk of Subsequent C. difficile Infection in Intensive Care Unit Patients.
  Tschudin-Sutter S, Carroll KC, Tamma PD, Sudekum ML, Frei R, Widmer AF, Ellis BC, Bartlett J, Perl TM Infection control and hospital epidemiology 2015 Nov 36 11 1324-9
- Protecting the frontline: designing an infection prevention platform for preventing emerging respiratory viral illnesses in healthcare personnel.
  Branch-Elliman W, Savor Price C, McGeer A, Perl TM Infection control and hospital epidemiology 2015 Mar 36 3 336-45
- Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).
  McCarty TP, Baddley JW, Walsh TJ, Alexander BD, Kontoyiannis DP, Perl TM, Walker R, Patterson TF, Schuster MG, Lyon GM, Wingard JR, Andes DR, Park BJ, Brandt ME, Pappas PG Medical mycology 2015 Jun 53 5 440-6
- Middle East respiratory syndrome coronavirus in healthcare settings.
  Al-Tawfiq JA, Perl TM Current opinion in infectious diseases 2015 Aug 28 4 392-6
- A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates.
  Yokoe DS, Anderson DJ, Berenholtz SM, Calfee DP, Dubberke ER, Ellingson KD, Gerding DN, Haas JP, Kaye KS, Klompas M, Lo E, Marschall J, Mermel LA, Nicolle LE, Salgado CD, Bryant K, Classen D, Crist K, Deloney VM, Fishman NO, Foster N, Goldmann DA, Humphreys E, Jernigan JA, Padberg J, Perl TM, Podgorny K, Septimus EJ, VanAmringe M, Weaver T, Weinstein RA, Wise R, Maragakis LL Infection control and hospital epidemiology 2014 Sep 35 Suppl 2 S21-31
- Multidrug-resistant gram-negative bloodstream infections among residents of long-term care facilities.
  Venkatachalam I, Yang HL, Fisher D, Lye DC, Moi Lin L, Tambyah P, Perl TM Infection control and hospital epidemiology 2014 May 35 5 519-26
- Ventilator-associated pneumonia: overdiagnosis and treatment are common in medical and surgical intensive care units.
  Nussenblatt V, Avdic E, Berenholtz S, Daugherty E, Hadhazy E, Lipsett PA, Maragakis LL, Perl TM, Speck K, Swoboda SM, Ziai W, Cosgrove SE Infection control and hospital epidemiology 2014 Mar 35 3 278-84
- Healthcare providers as sources of vaccine-preventable diseases.
  Sydnor E, Perl TM Vaccine 2014 Aug 32 38 4814-22
- Saving costs through the decontamination of the packaging of unused medical supplies using hydrogen peroxide vapor.
  Otter JA, Nowakowski E, Salkeld JA, Duclos M, Passaretti CL, Yezli S, Ross T, Carroll KC, Perl TM Infection control and hospital epidemiology 2013 May 34 5 472-8
- Hospital outbreak of Middle East respiratory syndrome coronavirus.
  Assiri A, McGeer A, Perl TM, Price CS, Al Rabeeah AA, Cummings DA, Alabdullatif ZN, Assad M, Almulhim A, Makhdoom H, Madani H, Alhakeem R, Al-Tawfiq JA, Cotten M, Watson SJ, Kellam P, Zumla AI, Memish ZA The New England journal of medicine 2013 Aug 369 5 407-16
- Combating the spread of carbapenemases in Enterobacteriaceae: a battle that infection prevention should not lose.
  Savard P, Perl TM Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2014 Sep 20 9 854-61
- Minimizing hair dispersal: Is this an opportunity for improvement in health care-acquired infection prevention?
  Mantyh CR, Xi H, Pearson L, Perl TM American journal of infection control 2017 Mar 45 3 308-310
- Medusa's ugly head again: from SARS to MERS-CoV.
  Perl TM, McGeer A, Price CS Annals of internal medicine 2014 Mar 160 6 432-3
- Approaches for preventing healthcare-associated infections: go long or go wide?
  Septimus E, Weinstein RA, Perl TM, Goldmann DA, Yokoe DS Infection control and hospital epidemiology 2014 Jul 35 7 797-801
- The challenges of carbapenemase-producing Enterobacteriaceae and infection prevention: protecting patients in the chaos.
  Savard P, Carroll KC, Wilson LE, Perl TM Infection control and hospital epidemiology 2013 Jul 34 7 730-9
- Clinical practice guidelines for antimicrobial prophylaxis in surgery.
  Bratzler DW, Dellinger EP, Olsen KM, Perl TM, Auwaerter PG, Bolon MK, Fish DN, Napolitano LM, Sawyer RG, Slain D, Steinberg JP, Weinstein RA Surgical infections 2013 Feb 14 1 73-156
- A request for an alliance in the battle for clean and safe hospital surfaces.
  Otter JA, Yezli S, Perl TM, Barbut F, French GL The Journal of hospital infection 2013 Aug 84 4 341-2
- The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel.
  Radonovich LJ, Bessesen MT, Cummings DA, Eagan A, Gaydos C, Gibert C, Gorse GJ, Nyquist AC, Reich NG, Rodrigues-Barradas M, Savor-Price C, Shaffer RE, Simberkoff MS, Perl TM BMC infectious diseases 2016 Jun 16 243
- Maintaining the momentum of change: the role of the 2014 updates to the compendium in preventing healthcare-associated infections.
  Septimus E, Yokoe DS, Weinstein RA, Perl TM, Maragakis LL, Berenholtz SM Infection control and hospital epidemiology 2014 May 35 5 460-3
- The prediction of complicated Clostridium difficile infections in children.
  Tschudin-Sutter S, Tamma PD, Milstone AM, Perl TM Infection control and hospital epidemiology 2014 Jul 35 7 901-3
- Predictors of first recurrence of Clostridium difficile infections in children.
  Tschudin-Sutter S, Tamma PD, Milstone AM, Perl TM The Pediatric infectious disease journal 2014 Apr 33 4 414-6
- Assessment of operating room airflow using air particle counts and direct observation of door openings.
  Teter J, Guajardo I, Al-Rammah T, Rosson G, Perl TM, Manahan M American journal of infection control 2017 May 45 5 477-482
- Preventing healthcare-associated transmission of the Middle East Respiratory Syndrome (MERS): Our Achilles heel.
  Balkhy HH, Perl TM, Arabi YM Journal of infection and public health 2016 May-Jun 9 3 208-12
- Saccharomyces boulardii probiotic-associated fungemia: Questioning the safety of this preventive probiotic's use.
  Martin IW, Tonner R, Trivedi J, Miller H, Lee R, Liang X, Rotello L, Isenbergh E, Anderson J, Perl T, Zhang SX Diagnostic microbiology and infectious disease 2016 Dec
- Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia.
  Al Ghamdi M, Alghamdi KM, Ghandoora Y, Alzahrani A, Salah F, Alsulami A, Bawayan MF, Vaidya D, Perl TM, Sood G BMC infectious diseases 2016 Apr 16 174
- The Creation of a Biocontainment Unit at a Tertiary Care Hospital: The Johns Hopkins Medicine Experience.
  Garibaldi BT, Kelen GD, Brower RG, Bova G, Ernst N, Reimers M, Langlotz R, Gimburg A, Iati M, Smith C, MacConnell S, James H, Lewin JJ, Trexler P, Black MA, Lynch C, Clarke W, Marzinke MA, Sokoll LJ, Carroll KC, Parish NM, Dionne K, Biddison EL, Gwon HS, Sauer L, Hill P, Newton SM, Garrett MR, Miller RG, Perl TM, Maragakis LL Annals of the American Thoracic Society 2016 Apr
- Postdischarge surveillance for infection following cesarean section: A prospective cohort study comparing methodologies.
  Halwani MA, Turnbull AE, Harris M, Witter F, Perl TM American journal of infection control 2016 Apr 44 4 455-7
- Triggering interventions for influenza: the ALERT algorithm.
  Reich NG, Cummings DA, Lauer SA, Zorn M, Robinson C, Nyquist AC, Price CS, Simberkoff M, Radonovich LJ, Perl TM Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015 Feb 60 4 499-504
- Operating room myths: what is the evidence for common practices.
  Pada S, Perl TM Current opinion in infectious diseases 2015 Aug 28 4 369-74
- Epidemiology of Candida kefyr in Patients with Hematologic Malignancies.
  Dufresne SF, Marr KA, Sydnor E, Staab JF, Karp JE, Lu K, Zhang SX, Lavallée C, Perl TM, Neofytos D Journal of clinical microbiology 2014 Mar
- Contact precautions: more is not necessarily better.
  Dhar S, Marchaim D, Tansek R, Chopra T, Yousuf A, Bhargava A, Martin ET, Talbot TR, Johnson LE, Hingwe A, Zuckerman JM, Bono BR, Shuman EK, Poblete J, Tran M, Kulhanek G, Thyagarajan R, Nagappan V, Herzke C, Perl TM, Kaye KS Infection control and hospital epidemiology 2014 Mar 35 3 213-21
- A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals: 2014 Updates.
  Yokoe DS, Anderson DJ, Berenholtz SM, Calfee DP, Dubberke ER, Ellingson KD, Gerding DN, Haas JP, Kaye KS, Klompas M, Lo E, Marschall J, Mermel LA, Nicolle LE, Salgado CD, Bryant K, Classen D, Crist K, Deloney VM, Fishman NO, Foster N, Goldmann DA, Humphreys E, Jernigan JA, Padberg J, Perl TM, Podgorny K, Septimus EJ, VanAmringe M, Weaver T, Weinstein RA, Wise R, Maragakis LL American journal of infection control 2014 Aug 42 8 820-8
- A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates.
  Yokoe DS, Anderson DJ, Berenholtz SM, Calfee DP, Dubberke ER, Ellingson KD, Gerding DN, Haas JP, Kaye KS, Klompas M, Lo E, Marschall J, Mermel LA, Nicolle LE, Salgado CD, Bryant K, Classen D, Crist K, Deloney VM, Fishman NO, Foster N, Goldmann DA, Humphreys E, Jernigan JA, Padberg J, Perl TM, Podgorny K, Septimus EJ, VanAmringe M, Weaver T, Weinstein RA, Wise R, Maragakis LL Infection control and hospital epidemiology 2014 Aug 35 8 967-77
- Methicillin-resistant Staphylococcus aureus transmission and infections in a neonatal intensive care unit despite active surveillance cultures and decolonization: challenges for infection prevention.
  Popoola VO, Budd A, Wittig SM, Ross T, Aucott SW, Perl TM, Carroll KC, Milstone AM Infection control and hospital epidemiology 2014 Apr 35 4 412-8
- Distinguishing community-associated from hospital-associated Clostridium difficile infections in children: implications for public health surveillance.
  Tschudin-Sutter S, Tamma PD, Naegeli AN, Speck KA, Milstone AM, Perl TM Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Dec 57 12 1665-72
- Universal Influenza Vaccination Among Healthcare Personnel: Yes We Should.
  Perl TM, Talbot TR, Open forum infectious diseases 2019 Apr 6 4 ofz096
- Managing Emerging Infectious Diseases: Should Travel Be the Fifth Vital Sign?
  Perl TM, Price CS, Annals of internal medicine 2020 04 172 8 560-561
- N95 Respirators vs Medical Masks in Outpatient Settings-Reply.
  Radonovich LJ, Simberkoff MS, Perl TM, JAMA 2020 02 323 8 789-790
- Efficacy and safety of a novel antimicrobial preoperative skin preparation.
  Crnich CJ, Pop-Vicas AE, Hedberg TG, Perl TM, Infection control and hospital epidemiology 2019 Oct 40 10 1157-1163
- "The Art of War" in the Era of Coronavirus Disease 2019 (COVID-19).
  Maxwell DN, Perl TM, Cutrell JB, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Mar
- N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial.
  Radonovich LJ, Simberkoff MS, Bessesen MT, Brown AC, Cummings DAT, Gaydos CA, Los JG, Krosche AE, Gibert CL, Gorse GJ, Nyquist AC, Reich NG, Rodriguez-Barradas MC, Price CS, Perl TM, JAMA 2019 09 322 9 824-833
- Personal protective equipment for viral hemorrhagic fevers.
  Raj D, Hornsey E, Perl TM, Current opinion in infectious diseases 2019 Aug 32 4 337-347
- Obstetricians on the Coronavirus Disease 2019 (COVID-19) Front Lines and the Confusing World of Personal Protective Equipment.
  Jamieson DJ, Steinberg JP, Martinello RA, Perl TM, Rasmussen SA, Obstetrics and gynecology 2020 06 135 6 1257-1263