Yu-Guang He, M.D.

Yu-Guang He, M.D.

  • Josephine Long Biddle Chair in Age-Related Macular Degeneration Research
  • Zora Meagher Macular Degeneration Research Professorship
  • Ophthalmology
  • Retina & Vitreous
  • Macular Degeneration


Yu‐Guang He, M.D., is a Professor in the Department of Ophthalmology at UT Southwestern Medical Center, where he also serves as Director of the Vitreoretinal Fellowship Program. He specializes in retina and vitreous diseases, macular degeneration, and diabetic retinopathy.

Dr. He earned his medical degree at Tongji Medical University in Wuhan, China. He completed a research fellowship and an ophthalmology residency at UT Southwestern before receiving advanced training through a fellowship in ​surgical and medical retina at the University of Washington affiliated hospitals. 

Certified by the American Board of Ophthalmology, Dr. He joined the UT Southwestern faculty in 2001. 

The author of numerous papers, book chapters, and presentations, Dr. He is an internationally invited lecturer on vitreoretinal diseases and macular degeneration. He holds the Josephine Long Biddle Chair in Age-Related Macular Degeneration Research and the Zora Meagher Macular Degeneration Research Professorship. 

Dr. He is a member of numerous professional organizations, including the American Academy of Ophthalmology, the American Society of Retina Specialists, the Dallas County Medical Society, the Texas Chinese Physicians Association, the Texas Medical Association, and the Texas Ophthalmological Association.

Dr. He has been named both a D Magazine Best Doctor and a Texas Monthly Super Doctor.

Meet Dr. He

Yu-Guang He, M.D., specializes in the diagnosis and treatment of vitreoretinal disorders, both acute and chronic in nature. A faculty member in the Department of Ophthalmology at UT Southwestern Medical Center since 2001, Dr. He remains fascinated by ophthalmology and the extent to which eye disease oftentimes involves more than the body’s visual system.

"As both a clinician and researcher, I’ve seen first-hand the refinement of procedures to treat emergent conditions like a retinal detachment. Changes in surgical techniques have resulted in smaller incisions, and no sutures, for the patient.”

“The eye is the only organ through which you can look to the brain, and it tells us a lot,” says Dr. He, who often diagnoses diabetes in patients by the distinct pattern the disease leaves on the retina. Other disorders Dr. He specializes in include macular degeneration; retinal vein occlusion; retinal holes, tears, and detachments; lattice degeneration; retinopathy of prematurity; ruptured globe injury; macular puckers; choroidal nevus; uveal melanoma; and central serious retinopathy.

A self-described “Texan by choice,” Dr. He became an ophthalmologist as the result of a series of serendipitous events in China in the early 1980s. At the conclusion of medical school in China, the government informed him he would specialize in ophthalmology.

“There was a shortage of ophthalmologists in China,” says Dr. He, who sees patients in the Aston and Fort Worth Ophthalmology clinics.

“I love the active, problem-solving aspects of ophthalmology,” says Dr. He. “I can see what’s causing my patients’ vision problems and put together a customized treatment plan for the patient. There’s been incredible progress from just 10 years ago, and I look forward to helping many more patients get through acute and chronic retinal problems.”

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Education & Training
  • Residency - UT Southwestern Medical School (1996-1999), Ophthalmology
  • Internship - UT Southwestern Medical School (1995-1996), Transitional Year
  • Fellowship - UT Southwestern Medical School (1988-1990), Cornea Service
  • Fellowship - University of Washington Affiliated Hospitals (1999-2001), Vitreoretinal
  • Residency - Tongii Medical University, Ophthalmology
  • Medical School - Tongji Medical University (1978-1982)
Professional Associations & Affiliations
  • TMA (Texas Medical Association)
  • ASRS (American Society of Retina Specialists)
  • ARVO (Assn. for Research in Vision & Ophthalmology)
  • AAO (American Academy of Ophthalmology)
Honors & Awards
  • Small Business Innovation Research Award (NEI/NIH) 2010, Validation of a Novel Vision Assessment System
  • Endowed Chair 2011, Josephine Lond Biddle Chair in Age-Related Macular Degeneration Research
  • D Magazine 2013, Best Doctors in Dallas
  • Texas Monthly Magazine 2014, Super Doctors
Books & Publications
  • Transplantation of RPE cells
  • Ocular immunology
  • Ocular cell biology

Clinical Focus

  • Retina & Vitreous
  • Macular Degeneration
  • Diabetic Retinopathy
  • Ophthalmology
  • Retinoblastoma
  • Diseases of the retina and vitreous
  • Vitreoretinal diseases
  • Ocular oncology
  • Uveal melanoma

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Q&A by Dr. He