- Residency - UT Southwestern Medical School (1996-1999), Ophthalmology
- Internship - UT Southwestern Medical School (1995-1996), Transitional Year
- Fellowship - UT Southwestern Medical School (1988-1990), Cornea Service
- Fellowship - University of Washington Affiliated Hospitals (1999-2001), Vitreoretinal
- Residency - Tongii Medical University, Ophthalmology
- Medical School - Tongji Medical University (1978-1982)
Yu-Guang He, M.D.
- Zora Meagher Macular Degeneration Research Professorship
- Josephine Long Biddle Chair in Age-Related Macular Degeneration Research
- Retina & Vitreous
- Macular Degeneration
Yu‐Guang He, M.D., is a Professor in the Department of Ophthalmology at UT Southwestern Medical Center, where he also serves as Director of the Vitreoretinal Fellowship Program. He specializes in retina and vitreous diseases, macular degeneration, and diabetic retinopathy.
Dr. He earned his medical degree at Tongji Medical University in Wuhan, China. He completed a research fellowship and an ophthalmology residency at UT Southwestern before receiving advanced training through a fellowship in surgical and medical retina at the University of Washington affiliated hospitals.
Certified by the American Board of Ophthalmology, Dr. He joined the UT Southwestern faculty in 2001.
The author of numerous papers, book chapters, and presentations, Dr. He is an internationally invited lecturer on vitreoretinal diseases and macular degeneration. He holds the Josephine Long Biddle Chair in Age-Related Macular Degeneration Research and the Zora Meagher Macular Degeneration Research Professorship.
Dr. He is a member of numerous professional organizations, including the American Academy of Ophthalmology, the American Society of Retina Specialists, the Dallas County Medical Society, the Texas Chinese Physicians Association, the Texas Medical Association, and the Texas Ophthalmological Association.
Dr. He has been named both a D Magazine Best Doctor and a Texas Monthly Super Doctor.
Meet Dr. He
Yu-Guang He, M.D., specializes in the diagnosis and treatment of vitreoretinal disorders, both acute and chronic in nature. A faculty member in the Department of Ophthalmology at UT Southwestern Medical Center since 2001, Dr. He remains fascinated by ophthalmology and the extent to which eye disease oftentimes involves more than the body’s visual system.
"As both a clinician and researcher, I’ve seen first-hand the refinement of procedures to treat emergent conditions like a retinal detachment. Changes in surgical techniques have resulted in smaller incisions, and no sutures, for the patient.”
“The eye is the only organ through which you can look to the brain, and it tells us a lot,” says Dr. He, who often diagnoses diabetes in patients by the distinct pattern the disease leaves on the retina. Other disorders Dr. He specializes in include macular degeneration; retinal vein occlusion; retinal holes, tears, and detachments; lattice degeneration; retinopathy of prematurity; ruptured globe injury; macular puckers; choroidal nevus; uveal melanoma; and central serious retinopathy.
A self-described “Texan by choice,” Dr. He became an ophthalmologist as the result of a series of serendipitous events in China in the early 1980s. At the conclusion of medical school in China, the government informed him he would specialize in ophthalmology.
“There was a shortage of ophthalmologists in China,” says Dr. He, who sees patients in the Aston and Fort Worth Ophthalmology clinics.
“I love the active, problem-solving aspects of ophthalmology,” says Dr. He. “I can see what’s causing my patients’ vision problems and put together a customized treatment plan for the patient. There’s been incredible progress from just 10 years ago, and I look forward to helping many more patients get through acute and chronic retinal problems.”
- TMA (Texas Medical Association)
- ASRS (American Society of Retina Specialists)
- ARVO (Assn. for Research in Vision & Ophthalmology)
- AAO (American Academy of Ophthalmology)
- Small Business Innovation Research Award (NEI/NIH) 2010, Validation of a Novel Vision Assessment System
- Endowed Chair 2011, Josephine Lond Biddle Chair in Age-Related Macular Degeneration Research
- D Magazine 2013, Best Doctors in Dallas
- Texas Monthly Magazine 2014, Super Doctors
Recovery of visual functions in a mouse model of Leber congenital amaurosis.
Van Hooser JP, Liang Y, Maeda T, Kuksa V, Jang GF, He YG, Rieke F, Fong HK, Detwiler PB, Palczewski K The Journal of biological chemistry 2002 May 277 21 19173-82
Role of TRAIL and IFN-gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye.
Wang S, Boonman ZF, Li HC, He Y, Jager MJ, Toes RE, Niederkorn JY Journal of immunology (Baltimore, Md. : 1950) 2003 Sep 171 6 2789-96
Expression and possible function of IL-2 and IL-15 receptors on human uveal melanoma cells.
He YG, Mayhew E, Mellon J, Niederkorn JY Investigative ophthalmology & visual science 2004 Dec 45 12 4240-6
Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues.
Lindqvist A, He YG, Andersson S The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005 Nov 53 11 1403-12
Progressive outer retinal necrosis complicated by combined central retinal vein and central retinal artery occlusions.
Tran PT, Crow RW, Blomquist PH, He YG Retinal cases & brief reports 2007 1 3 138-40
Cystoid and diabetic macular edema treated with nepafenac 0.1%.
Hariprasad SM, Callanan D, Gainey S, He YG, Warren K Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2007 Dec 23 6 585-90
The effect of intravitreal triamcinolone on intraocular pressure.
Kramar M, Vu L, Whitson JT, He YG Current medical research and opinion 2007 Jun 23 6 1253-8
Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.
Chen PW, Mellon JK, Mayhew E, Wang S, He YG, Hogan N, Niederkorn JY Experimental eye research 2007 Nov 85 5 617-25
Transplanted corneal graft with metastatic cholangiocarcinoma to the donor eye.
Yao X, Lee M, Ying F, Huang L, Qi W, Zhao P, He YG Eye & contact lens 2008 Nov 34 6 340-2
PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation.
Yang W, Li H, Chen PW, Alizadeh H, He Y, Hogan RN, Niederkorn JY Investigative ophthalmology & visual science 2009 Jan 50 1 273-80
Functional analysis of platelet-activating factor in the retinal pigment epithelial cells and choroidal endothelial cells.
He YG, Wang H, Zhao B, Hsu M, Liao D, Owens J, Johnston J Current eye research 2009 Nov 34 11 957-65
Elevated vascular endothelial growth factor level in Coats' disease and possible therapeutic role of bevacizumab.
He YG, Wang H, Zhao B, Lee J, Bahl D, McCluskey J Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2010 Oct 248 10 1519-21
Reticular drusen associated with geographic atrophy in age-related macular degeneration.
Schmitz-Valckenberg S, Alten F, Steinberg JS, Jaffe GJ, Fleckenstein M, Mukesh BN, Hohman TC, Holz FG Investigative ophthalmology & visual science 2011 Aug 52 9 5009-15
miRNAs as potential therapeutic targets for age-related macular degeneration.
Wang S, Koster KM, He Y, Zhou Q Future medicinal chemistry 2012 Mar 4 3 277-87
FEASIBILITY OF A NOVEL REMOTE DAILY MONITORING SYSTEM FOR AGE-RELATED MACULAR DEGENERATION USING MOBILE HANDHELD DEVICES: Results of a Pilot Study.
Kaiser PK, Wang YZ, He YG, Weisberger A, Wolf S, Smith CH Retina (Philadelphia, Pa.) 2013 Apr
Handheld shape discrimination hyperacuity test on a mobile device for remote monitoring of visual function in maculopathy.
Wang YZ, He YG, Mitzel G, Zhang S, Bartlett M Investigative ophthalmology & visual science 2013 Aug 54 8 5497-505
Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2).
Danis RP, Domalpally A, Chew EY, Clemons TE, Armstrong J, SanGiovanni JP, Ferris FL Investigative ophthalmology & visual science 2013 Jul 54 7 4548-54
Dexamethasone intravitreal implant (Ozurdex) for the treatment of pediatric uveitis.
Bratton ML, He YG, Weakley DR Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 2014 Apr 18 2 110-3
- Recovery of visual functions in a mouse model of Leber congenital amaurosis.
- Transplantation of RPE cells
- Ocular immunology
- Ocular cell biology
- Retina & Vitreous
- Macular Degeneration
- Diabetic Retinopathy
Q&A by Dr. He
Articles by Dr. He
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Fort Worth, Texas 76104 817-429-3050