An accurate liver cancer diagnosis is the first step in
determining the optimal treatment plan,
which our team creates specifically for each patient. Once we have a diagnosis,
we stage the cancer, which means we see how large it is and if it has spread.
At UT Southwestern Medical Center, the Harold C.
Simmons Comprehensive Cancer Center has highly trained specialists and the most
advanced equipment to diagnose and stage liver cancer. Our radiologists
specialize in gastrointestinal cancers and have expertise in abdominal magnetic
resonance imaging (MRI), a common tool used to stage (and sometimes diagnose)
liver cancer.
Diagnosing Liver Cancer
Our liver cancer team, including national experts in early detection and diagnosis, helped define the criteria currently used to diagnose liver cancer in the United States. To diagnose liver cancer, we might perform one or more of
the following:
- Physical
exams to check the abdomen for lumps, swelling, or signs of
jaundice.
- Blood
tests to measure the level of proteins called alpha fetoprotein
(AFP), or carbohydrate antigen (CA) 19-9, which can be elevated in many
cases of primary liver cancer. Other blood tests can show how well the
liver is functioning.
- Imaging with computed
tomography (CT) or magnetic resonance
imaging (MRI).
- Biopsy to remove
a sample of liver tissue for examination under a microscope. However, if
the patient has hepatocellular carcinoma (HCC), the most common type
of liver cancer, we can diagnose without a biopsy if it has a
characteristic appearance on an MRI or CT scan.
- Molecular
testing to gather biomarker information about a patient’s unique
tumor to help determine if specific treatments will be effective.
Liver Cancer Staging
After the diagnostic testing to confirm liver cancer, we’ll
conduct additional tests to learn more about the tumor and determine how much
it has spread, if any.
At UT Southwestern, imaging tests used to diagnose and stage
liver cancer might include ultrasound, computed
tomography (CT scan), and magnetic resonance
imaging (MRI).
Information from staging tests helps us figure out if the
cancer:
- Is in
one area and can be completely removed
- Is in
one area but cannot be completely removed safely
- Has
spread throughout the liver or to other parts of the body
With this information, our experienced team will discuss the
results with the patient and determine the best treatment strategy for that
situation.
