Xiao-Fei Kong, M.D., Ph.D.

Xiao-Fei Kong, M.D., Ph.D.

  • Internal Medicine - Digestive and Liver Diseases
  • Celiac Disease
  • Common variable immunodeficiency


Xiao-Fei Kong, M.D., Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He specializes in celiac disease, common variable immunodeficiency, Down syndrome, inflammatory bowel disease, and rare liver disease.

Originally from China, Dr. Kong was educated and trained across three continents. He earned his medical degree at Yangzhou University Medical College in Jiangsu, China, and completed a residency in internal medicine at Ruijin Hospital and Shanghai Jiaotong University. He then obtained a doctoral degree in immunology and genetics from the Sorbonne University in Paris, France, under the mentorship of Jean-Laurent Casanova, M.D., Ph.D. As a clinical scholar, Dr. Kong earned a master's degree in translational medicine from the Rockefeller University in New York. He then received additional internal medicine residency training at the Icahn School of Medicine at Mount Sinai, also in New York, followed by advanced fellowship training in gastroenterology and a one-year faculty appointment at Columbia University Medical Center.

Certified by the American Board of Internal Medicine in internal medicine and gastroenterology, he joined the UT Southwestern faculty in 2022.

An investigator on numerous clinical projects, Dr. Kong's research interests include celiac disease, inflammatory bowel disease, inborn errors of immunity, and rare liver diseases. His work has led to the discovery of several new genetic diseases, including human SPPL2A deficiency, inherited STAT1 disorders, and interferonopathy in Down syndrome. He has published numerous articles in peer-reviewed journals and presented widely at national and international conferences.

Dr. Kong is an active member of several professional organizations, including the American Association for the Study of Liver Diseases, the American Gastroenterological Association, and the European Society for Immunodeficiencies.

In 2021, he received a career development award from the National Institute of Diabetes and Digestive and Kidney Diseases.

Education & Training
  • Medical School - Yangzhou University Medical College (1996-2001)
  • Other Post Graduate Training - The Rockefeller University (2012-2015)
  • Residency - Icahn School of Medicine at Mount Sinai /Queens Hospital Center (2015-2018), Internal Medicine
  • Fellowship - Columbia University - New York Presbyterian Hospital (2018-2021), Gastroenterology
Professional Associations & Affiliations
  • American Association for the Study of Liver Diseases
  • American Gastroenterological Association
  • Clinical Immunology Society
  • European Society for Immunodeficiencies
Honors & Awards
  • Clinical and Translational Science Award 2014, The Rockefeller University
  • Jérôme Lejeune Foundation Award 2013
  • Stony Wold-Herbert Fund Award 2012
  • C. H. Li Memorial Scholar Award 2009, The Rockefeller University
  • Keystone Symposia Travel Award 2009
  • Chen-Guang Plan Scholar 2007, Shanghai Education Development Foundation
  • First-Prize Scholarship 2004, Shanghai Jiaotong University, School of Medicine
Books & Publications
  • Celiac disease
  • Human genetics
  • Immunology
  • Inflammatory bowel disease
  • Rare digestive and liver diseases

Clinical Focus

  • Celiac Disease
  • Common variable immunodeficiency
  • Down syndrome
  • Inflammatory Bowel Disease
  • Rare liver disease

See More