Peyronie's Disease

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UT Southwestern Medical Center’s team of urologists expertly diagnoses and treats men suffering from Peyronie’s disease, an often painful and life-altering penile condition.

Leading-Edge Treatment for a Sensitive Problem

Peyronie's disease is a condition in which scar tissue develops beneath the skin of the penis, causing it to become curved, lumpy, and hard. The condition can be painful; cause problems with voiding, erections, and sexual intercourse; and diminish emotional well-being and quality of life.

Peyronie’s disease is usually caused by an injury to the penis, often sustained during intercourse. Certain connective tissue disorders and a family history of the condition also increase the risk of developing it. Although Peyronie’s disease is likely underreported, about six in 100 men between the ages of 40 and 70 are believed to suffer from it.

UT Southwestern’s experienced urologists use the most advanced tools and techniques – from collagenase injections to minimally invasive surgery – to treat men with Peyronie’s disease.

Diagnosis of Peyronie’s Disease

Peyronie’s disease often can be diagnosed with only a physical exam. In some cases, the urologist will inject a drug into the penis and order imaging studies such as an ultrasound to visualize the scar tissue and blood flow.

Treatment of Peyronie’s Disease

Because Peyronie’s disease resolves on its own in only a very few cases, most men with the condition eventually require some type of treatment, depending on the severity.

Treatments for Peyronie’s disease include:

  • Oral medications aimed at reducing scar tissue and inflammation
  • Injections of agents such as interferon and collagenase, to diminish scar tissue and swelling
  • Minimally invasive, same-day surgery
  • Traditional open surgery

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