Cornea and External Eye Diseases

Appointment New Patient Appointment or 214-645-2020

UT Southwestern Medical Center’s ophthalmologists have specialized training in identifying and treating cornea disease and other external eye conditions. We offer advanced treatments, including specialized medications and laser surgery, based on the latest research for successful patient outcomes.

Experienced Care for Cornea and External Eye Diseases

The cornea is the clear, outer layer covering the front of the eye. It acts as a barrier to protect the eye from foreign objects, helps with vision by focusing light, and filters ultraviolet rays that enter the eye.

The cornea can usually heal itself after scratches or minor injuries. However, the cornea and other external eye structures require medical treatment for more serious injuries, allergies, inflammation, infections, corneal dystrophies, and a wide range of other conditions.

At UT Southwestern, our eye specialists perform thousands of outpatient surgeries each year, including cornea transplants and other procedures. This level of experience means safe, effective care for our patients and the best possible outcomes.

Types of Cornea and External Eye Diseases

Some of the cornea and external eye conditions treated at UT Southwestern include:

  • Acanthamoeba keratitis: This rare but serious infection in the cornea is most often seen in people who wear soft contact lenses and who don’t follow care and wear instructions. Patients initially have eye pain, redness, sensitivity to light, and blurry vision. If untreated, it can lead to permanent vision loss. 
  • Benign tumors and pseudotumors
  • Blepharitis: Inflammation of the eyelid
  • Conjunctivitis: Sometimes called “pink eye,” conjunctivitis means inflammation of the outer covering of the white part of the eye, the conjunctiva. It can result from allergy, irritation, viral infection, or bacterial infection.  Each type has its own symptoms and signs. If an eye is red for more than a day or two, has a lot of discharge, or is painful or blurry, the patient should be examined. 
  • Corneal dystrophies: These are a group of conditions of the cornea. Some are mild changes that a doctor can see only with a microscope and which don’t cause any problems. Others, however, can lead to corneal haze or opacities and can affect vision. Many corneal dystrophies run in families.
  • Contact lens problems and management of lens-related complications
  • Dry eye: As people age, the eye loses some of its ability to make tears. Because the eye is designed to work “under water,” inadequate tears can cause blurry vision as well as irritation. This condition is often treated by using artificial tears, drops, and ointments. There are also medications available to help the eye to make more of its own tears, including Restasis and Xiidra
  • Excessive tearing: Often referred to as epiphora, this is a condition in which the eye tears too much. It can be caused by too much tear production, by inadequate drainage of the tears from the eyes, or by malposition of the lower eyelids. Generally, inadequate drainage and malposition of the lids can be surgically corrected.
  • Fuchs’ corneal dystrophy: This condition affects the innermost layer of the cornea, the endothelium, causing it to lose the ability to keep fluid from soaking into the cornea.  If the endothelium needs to be replaced, then either DSAEK or DMEK is performed (see below).
  • Herpes keratitis: This inflammation and infection of the cornea can be caused by either the herpes simplex virus, which causes the common fever blisters, or by the herpes zoster virus (same as the chicken pox virus) that causes shingles. Both can result in scarring of the cornea and inflammation inside the eye. Patients with herpes simplex infection might experience fever blisters, red eye, blurry vision, and light sensitivity. Patients with herpes zoster might experience mid-face breakouts with shingles and considerable pain. Patients should seek care promptly.
  • Injuries to the cornea, including foreign objects lodged in the surface of the eye
  • Keratitis: Inflammation or infection of the cornea. There are many causes, but symptoms generally include sensitivity to light, blurry vision, and irritation. This generally needs evaluation and treatment.
  • Keratoconus: In some people, the cornea is weak and tends to lose its shape easily and over time, becoming cone shaped and resulting in blurry, out-of-focus vision. 
  • Photokeratitis: Photokeratitis is an inflammation of the cornea caused by exposure to light. Exposure can be from welding, too much sun exposure, or overexposure to UV light, such as from a tanning booth. It generally heals completely but can be quite uncomfortable.
  • Presbyopia (age-related farsightedness), nearsightedness, farsightedness, and astigmatism: These conditions affect people as they age, especially past age 40. when the natural lens inside the eye, which is behind the pupil, becomes stiffer and can’t change shape as easily for either near or far vision. Prescription glasses are generally the answer.

Normal vision in sight for cornea transplant patient

Glenda Marshall struggled for decades with thick glasses and foggy vision. Now following a corneal transplantation she received at UT Southwestern Medical Center, she’s seeing better than ever.

Causes of Cornea and External Eye Diseases

Medical experts don’t fully understand what causes some conditions affecting the cornea and external eye structures. Some well-known causes include:

  • Injury or trauma
  • Infection caused by bacteria, viruses, fungi, or parasites
  • Hereditary conditions
  • Allergic reactions to medications

Symptoms

Because there are many cornea and external eye conditions, the symptoms are wide-ranging and include:

  • Eye pain
  • Sensitivity to light
  • Blurry, reduced, or distorted vision
  • Excessing tearing
  • Redness, itching, burning, stinging, or inflammation in the eye
  • Discharge from the eye
  • Headache, nausea, fatigue
  • Feeling of having something in the eye
  • Poor night vision
  • Cloudy cornea

Diagnosis

Our ophthalmologists begin with a comprehensive eye exam, which includes:

  • Vision test
  • Dilated eye test to allow the physician to examine structures inside the eye
  • Tonometry, a painless test that measures pressure inside the eye

Other tests we might perform include:

  • Slit-lamp examination to look at the structures at the front of the eye
  • Contrast sensitivity and glare testing
  • Corneal topography to map the cornea’s surface
  • Pachymetry to measure the cornea’s thickness
  • Keratometry to measure the curve of the cornea
  • Blood tests to check for infection or inflammatory disorders

Treatment for Cornea and External Eye Diseases

Treatment options for conditions affecting the cornea and external eye structures vary depending on the specific condition and its severity. For common conditions such as allergies and minor injuries and infections, we offer:

  • Antihistamine decongestant eyedrops for allergic conditions
  • Antibacterial, antiviral, antifungal, or steroid eyedrops for infections and inflammation
  • Eye ointments to reduce symptoms

For more advanced or severe conditions, our treatment options include:

  • Glasses or contact lenses
  • Specialty contact lenses
  • Surgery to remove foreign objects and repair injuries to the cornea
  • Laser surgery to reshape and restore the cornea
  • Corneal grafts and corneal transplants

Our specialized corneal treatments include:

  • Corneal cross-linking: A special procedure performed to increase the strength of the cornea for people with keratoconus, making the cornea less likely to develop further conical changes.
  • Corneal inlays: Small acrylic implants that are placed in the cornea. They are not used commonly but can treat high or irregular astigmatism (misshaped cornea).
  • Corneal transplantation: A highly successful surgical procedure in which the patient's own cornea is replaced with a human donor's cornea. It's usually done for a corneal scar or irregularity, which can be caused by infection, trauma, genetic condition (like keratoconus), or degeneration. Newer techniques allow for the transplantation of only one layer of the cornea when appropriate.  
  • DALK (deep anterior lamellar keratoplasty): If the cornea is scarred or misshapen, replacement can mean that clear vision can be restored. DALK is one of the newer methods of replacing a cornea. It leaves the patient’s innermost corneal layer, resulting in less chance of complications with the new cornea.
  • DMEK (Descemet’s membrane endothelial keratoplasty): When the inner layer of the cornea – which is responsible for keeping the fluid inside of the eye from soaking into the cornea – fails, the cornea swells and vision gets cloudy. DMEK allows doctors to replace just the inner layer of the cornea, which is about as thick as a piece of plastic wrap.
  • DSAEK (Descemet’s stripping automated endothelial keratoplasty): This is a procedure similar to DMEK.

Related Conditions and Treatments

See More

Find a Clinical Trial

Search for opportunities to participate in a vision or eye-related research study.

StudyFinder

Award-Winning Care

We’re one of the world’s top academic medical centers, with a unique legacy of innovation in patient care and scientific discovery.  

Why UT Southwestern

MyChart

Our secure online portal for patients makes it easy to communicate with your doctor, access test results, and more.

Log In

Related Clinics

Showing 5 locations

Laser Center for Vision Care

at Outpatient Building 1801 Inwood Road, 5th Floor
Dallas, Texas 75390
214-645-2027 Directions Parking Info

Ophthalmology

at UT Southwestern Monty and Tex Moncrief Medical Center at Fort Worth 600 South Main Street, 1st Floor, Suite 1.500
Fort Worth, Texas 76104
817-429-3050 Directions

Ophthalmology

at UT Southwestern Frisco 12500 Dallas Parkway, 2nd Floor
Frisco, Texas 75033
469-604-9000 Directions Parking Info

Ophthalmology Clinic

at James W. Aston Ambulatory Care Center 5303 Harry Hines Blvd., 6th Floor
Dallas, Texas 75390
214-645-2020 Directions Parking Info

UT Southwestern Medical Group at North Dallas - Ophthalmology

12606 Greenville Avenue, 1st Floor, Suite 180
Dallas, Texas 75243
214-645-0950 Directions