John Cain, M.D.

Peter O'Donnell Jr. Brain Institute

Psychiatry
Adult Psychiatry
Mood and Anxiety Disorders

Effective Jan. 31, 2025, John Cain, M.D. will be closing his practice at UT Southwestern Medical Center.

The clinic will be happy to recommend a physician to assume your care. Patients can obtain a copy of their medical records by calling 214-645-3030 or by email at medical.records@utsouthwestern.edu.

Biography

Dr. Cain was named a Super Doctor by Texas Monthly in 2018.

Education & Training

Medical School - UT Health Science Center McGovern Medical School (1978-1982)
Internship - UT Health Science Center McGovern Medical School (1982-1983), Internal Medicine & Psychiatry
Residency - UT Health Science Center McGovern Medical School (1983-1985), Psychiatry
Fellowship - University of California at San Diego School of Medicine (1985-1987), Biological Psychiatry

Books & Publications

Publications
- Moclobemide in social phobia: a controlled dose-response trial.
  Noyes R, Moroz G, Davidson JR, Liebowitz MR, Davidson A, Siegel J, Bell J, Cain JW, Curlik SM, Kent TA, Lydiard RB, Mallinger AG, Pollack MH, Rapaport M, Rasmussen SA, Hedges D, Schweizer E, Uhlenhuth EH Journal of clinical psychopharmacology 1997 Aug 17 4 247-54
- Are fluoxetine plasma levels related to outcome in obsessive-compulsive disorder?
  Koran LM, Cain JW, Dominguez RA, Rush AJ, Thiemann S The American journal of psychiatry 1996 Nov 153 11 1450-4
- The effects of fluoxetine on the polysomnogram of depressed outpatients: a pilot study.
  Hendrickse WA, Roffwarg HP, Grannemann BD, Orsulak PJ, Armitage R, Cain JW, Battaglia J, Debus JR, Rush AJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994 Apr 10 2 85-91
- The effects of nefazodone on sleep architecture in depression.
  Armitage R, Rush AJ, Trivedi M, Cain J, Roffwarg HP, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994 Apr 10 2 123-7
- Poor response to fluoxetine: underlying depression, serotonergic overstimulation, or a "therapeutic window"?
  Cain JW The Journal of clinical psychiatry 1992 Aug 53 8 272-7
- Biological and cognitive predictors of response to acute treatment in depressed outpatients.
  Rush AJ, Gullion CM, Cain JW, Roffwarg HP Clinical neuropharmacology 1992 15 Suppl 1 Pt A 576A-577A
- Hypertension associated with oral administration of physostigmine in a patient with Alzheimer's disease.
  Cain JW The American journal of psychiatry 1986 Jul 143 7 910-2

Clinical Focus

Adult Psychiatry
Mood and Anxiety Disorders