Radiation Oncology

Types of Treatment

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A cancer diagnosis can be frightening. At UT Southwestern, patients can take comfort in the experience and expertise each team member brings to help them on their treatment journey.

With some of the most sophisticated treatment machines capable of treating all types of cancer, our team of experts, which includes radiation oncologists, physicists, dosimetrists, radiation biologists, therapists, nurses, and other clinical staff, are specially trained to treat cancer. In addition, we work collaboratively with other departments such as  surgical oncology, medical oncology,  radiology,  and  pathology  to provide each patient the most comprehensive and effective treatment plan possible. Our multidisciplinary approach coupled with the most advanced technology available means our patients have the highest possibility for superior treatment outcomes.

Treatment therapies are chosen based on each patient’s specific cancer and where it’s located. Through computer targeting, each treatment delivers a high dose of radiation precisely to a tumor, which kills cancer cells while sparing surrounding healthy tissue.

External beam radiation therapy

The most common type of radiation therapy is external beam radiation therapy (EBRT). During EBRT, a linear accelerator (linac) is used to send high-energy X-rays or gamma-rays to the tumor. Because of the precision we use during treatment, we’re able to send higher doses of radiation into the tumor without damaging surrounding healthy tissue.

Due to breathing and digestion, tumors in the body are constantly moving. To compensate for this, we use advanced image-guided systems to allow for that motion. At times, motion-control devices are used as well.

There are various types of external radiation therapy – all of which are noninvasive and done on an outpatient basis. Your radiation oncologist will determine the best course of treatment for the specific cancer and tumor. Types of external beam radiation include:

Stereotactic ablative radiation therapy (SAbR)/stereotactic body radiation therapy (SBRT)

SAbR, also known as SBRT, is used to treat tumors throughout the body, excluding the brain. Because the technology is so advanced and precise, we can administer a stronger dose of radiation at a time, which means fewer treatments – usually only three to five – and very little healthy tissue receives any radiation. Through innovation and clinical testing, our department pioneered the specialty, which has allowed its safe implementation throughout the field.

Image-guided radiation therapy (IGRT)

IGRT uses imaging technology to ensure accuracy and precisely target tumors, while adjusting for changes in tumor position during treatment. Imaging tests are performed in the same room as the patient’s treatment, immediately prior to, during treatment, or both.

3D conformal radiation therapy (3D-CRT)

Using a state-of-the-art computer program, 3D-CRT shapes the radiation beams to match the tumor’s size and shape in three dimensions. In doing so, we’re able to precisely target the tumor with higher levels of radiation and avoid healthy surrounding tissue. This technique is often used to create a sharp difference between treated and non-treated tissue.

Intensity-modulated radiation therapy (IMRT)

IMRT, a specialized form of 3D-CRT, allows us to control the intensity of the radiation beam in multiple small volumes to create precisely conformed dose distribution. The radiation beams may be re-shaped dozens or hundreds of times during treatment, resulting in radiation dose distribution that is “sculpted” in three dimensions. Rather than creating a uniform field of radiation, the radiation is delivered to precisely conform to the actual shape of the tumor, thus sparing healthy tissue.

Volumetric modulated arc therapy (VMAT)

VMAT, an advanced form of IMRT, delivers radiation while the treatment machine rotates around the patient. Continuous and coordinated changes in gantry speed, dose rate, and shape of the treatment aperture increase delivery treatment speeds two to eight times faster than conventional therapy, reducing a typical 10- to 15-minute treatment to less than one minute in some cases. Though it doesn’t reduce the total number of treatments patients require, the duration of each treatment is shorter which makes it more convenient for patients who must undergo multiple treatments. VMAT is particularly useful when delivering radiation near sensitive organs. Prostate  and  head and neck patients are often candidates for VMAT therapy.

Stereotactic radiosurgery (SRS)

SRS, first developed to treat brain tumors in a single dose, is a treatment where several high-dose radiation beams enter the body through various angles and intersect at the desired target, which allows for a concentrated dose to reach the tumor while limiting the radiation to nearby healthy tissues. Because of this, a one-time, high-dose application of radiation to a tumor can be used instead of multiple smaller doses typical in standard radiation treatment.

During SRS treatment, the patient lies on a couch that rotates 180 degrees for maximum targeting. SRS is used to treat brain  and  spine cancer, some  head and neck tumors,  as well as certain benign tumors and neurological conditions.

Partnering with Technology - The SAbR Approach

Proven effective in treating various types of cancer, we see evidence that SAbR may improve the survival for patients with metastatic disease.

Internal Beam Radiation Therapy

Brachytherapy is internal radiation therapy that involves a radioactive substance implanted in or near a cancerous tumor to provide direct, targeted treatment. Learn about brachytherapy.

Adaptive Therapy

Adaptive therapy provides precise, patient-specific treatment and must be done in concert with an understanding of how the body’s organ systems and immune system react, or fail to react, to cancer invasion. Adaptive radiation therapy can be performed with external beam radiation or with brachytherapy.

Using adaptive therapy, we’re exploring an innovative, more personalized way of delivering radiation treatments for our patients. This concept, PULSAR™, will be evaluated in a series of clinical trials at UT Southwestern over the next several years. PULSAR is based on a limited number of fairly large dose “pulses” in the ablative range that are separated in time by weeks or months. Learn more about adaptive therapy.

Adaptive therapy today is focused on conforming radiation to changing anatomy to make treatment more precise — but the dosage level and treatment schedule remain the same throughout despite the other changes. Moving forward, UTSW’s goal is to take data gleaned from research and artificial intelligence to make the care not just more precise, but more personal.

Steve Jiang, Ph.D., Professor; Vice Chair, Digital Health & AI; and Division Chief of Medical Physics & Engineering

For frequently asked questions about radiation therapy, please visit our patient resource page.