Radiation Oncology

Head and Neck Cancer

Appointment New Patient Appointment or 214-645-8525

UT Southwestern Medical Center’s head and neck cancer program includes a dedicated team that offers a level of expertise unmatched in Dallas and North Texas. We provide our patients with comprehensive, timely, and effective care.

As the only National Cancer Institute-designated comprehensive cancer center in North Texas, we deliver the best cancer care available today and push to discover new treatments. NCI designation means we offer patients the ability to participate in the broadest possible range of clinical trials, with access to potential therapies not available at other facilities.

The head and neck team works alongside radiation oncology physicists, dosimetrists, therapists, social workers, head and neck-focused nurses, and other dedicated clinical staff.

Meet Our Team

David Sher, M.D., M.P.H., Chief of Head & Neck Radiation Oncology Service

David Sher, M.D., M.P.H., Chief of Head & Neck Radiation Oncology Service

Rochelle Jackson, DNP, FNP-C

Rochelle Jackson, DNP, FNP-C

Dominic Moon, M.D.

Dominic Moon, M.D.

Educational Materials

Mask Process Simulation

During your CT simulation, a custom mask will be made so you can be placed in the same position during your radiation treatments. Lindsi Seaux, a radiation therapist in our Department, discusses the mask process, how it is made, and how it is used during your treatments. The purpose of a bite block and bolus is discussed as well.

Skin Care

Kaylee Cooper, a head and neck radiation oncology registered nurse in our Department, discusses skin changes that may occur during your radiation treatments and the different ways you can treat these changes at home.


During your radiation therapy many side effects can occur, such as a change in taste, an increase in saliva, and pain, making it difficult to preserve a diet and maintain a healthy weight. David Sher, M.D., M.P.H., Professor and Chief of Head and Neck Radiation Oncology services, discusses the importance of maintaining your nutrition during these treatments.

Dental Care

Kaylee Cooper talks about general dental and oral care during your radiation treatments.

Taste and Changes in the Mouth

Kaylee Cooper discusses the taste and changes in your mouth you may experience during radiation treatments.

Head and Neck Clinical Trials

As one of the top academic medical centers in the country and the only National Cancer Institute-designated cancer center in North Texas, we lead and participate in a number of clinical trials aimed at improving the outcomes of patients with cancer. The Department of Radiation Oncology enrolls approximately 200 new patients in clinical trials each year. 

Clinical trials are critical in developing new therapies for cancer and can mean having access to new medication, groundbreaking research, and additional clinical care. Our clinical trials team is comprised of radiation oncologists, radiation biologists, clinical research coordinators, quality assurance coordinators, and clinical data specialists. Learn about adaptive clinical trials.


NRG-HN001 - Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA). (STU 072014-041)

RTOG 3507 - KEYSTROKE: A Randomized Phase II Study of Pembrolizumab (KEYTRUDA) Plus Stereotactic Re-Irradiation versus SBRT Alone for Locoregionally Recurrent or Second Primary Head and Neck Carcinoma. (STU 2019-1316)

HYPORT-HN - A Randomized Non-Inferiority Phase II Study of Hypofractionated Post-Operative Radiation Therapy for Head and Neck Squamous Cell Carcinoma. (STU 2020-0522) Learn more about the HYPORT trial.

HYHOPE - A Phase I Study of De-Intensified Hypofractionated Radiation Therapy for Human Papilloma Virus-Associated Oropharynx Cancer. (STU 2020-1079) Learn more about the HYHOPE trial.

EA3161 - A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate Risk HPV-Positive OPCA. (STU 2020-1000) Learn more about EA3161 trial.

RTOG 1216 - A Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin versus Docetaxel versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck. (STU 022013-055) Learn more about the RTOG 1216 trial.

DARTBOARD - A Prospective Randomized Phase II Study of Daily Adaptive Radiotherapy to Better Organ-at-Risk Doses in Head and Neck Cancer. (STU 2021-041) Learn more about the DARTBOARD trial.


Registry Study to Evaluate the Clinical and Dosimetric Outcomes of Cancer Patients Adaptive Radiation Therapy (ART). (STU 2021-0529)

If you’re interested in a clinical trial, please talk to your doctor.

Learn more about clinical trials.

Helpful Resources