Sharon Nations, M.D.

Peter O'Donnell Jr. Brain Institute

Neurology
Neuromuscular Disorders
Neurophysiology (EMG)

Biography

Sharon Pond Nations, M.D., is a Professor in the Department of Neurology at UT Southwestern Medical Center. An expert in treating neuromuscular disorders, she also serves as Co-Director of the Muscular Dystrophy clinic at UT Southwestern.

Dr. Nations earned her medical degree at the University of Texas Medical Branch at Galveston. She completed a residency in neurology at Baylor College of Medicine and received advanced training in neurophysiology through a fellowship at UT Southwestern.

Certified by the American Board of Psychiatry and Neurology, Dr. Nations joined the UT Southwestern faculty in 1996.

Dr. Nations’ research interests include amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease; myasthenia gravis; myopathies; and chronic inflammatory demyelinating polyneuropathy (CIDP), and she has been involved in multiple clinical trials in these areas. She serves as a reviewer for Archives of Neurology, Neurology, Clinical Neuromuscular Disorders, and Muscle & Nerve.

Dr. Nations is a member of the American Academy of Neurology and the American Association of Neuromuscular & Electrodiagnostic Medicine.

Education & Training

Medical School - University of Texas Medical Branch at Galveston (1977-1981)
Internship - North Carolina Baptist Hospital (1981-1982), Neurology
Residency - Baylor College of Medicine (1982-1985), Neurology
Fellowship - Parkland Health and Hospital System (1995-1996), Neurophysiology

Professional Associations & Affiliations

American Academy of Neurology
American Association of Neuromuscular & Electrodiagnostic Medicine

Books & Publications

Books
- Infectious and Granulomatous Neuropathies in Bromberg MG and Smith AG (eds). Handbook of Peripheral Neuropathy
  Nations SP, Trivedi JR, Wolfe GI, New York, Marcel Dekker
- Motor Neuron Diseases in Braddom RL, et al. (eds). Physical Medicine and Rehabilitation
  Khanna P, Nations SP, Trivedi JR (2007), Saunders Elsevier
- A 34-Year-Old Man with Right Hand and Left Foot Numbness in Zhou L, Burns DK, Cai C (eds). A Case-based Guide to Neuromuscular Pathology
  Nations SP, Burns DK (2020), Switzerland, Springer Nature
Publications
- Plasma creatinine and oxidative stress biomarkers in amyotrophic lateral sclerosis.
  Mitsumoto H, Garofalo DC, Santella RM, Sorenson EJ, Oskarsson B, Fernandes JAM, Andrews H, Hupf J, Gilmore M, Heitzman D, Bedlack RS, Katz JS, Barohn RJ, Kasarskis EJ, Lomen-Hoerth C, Mozaffar T, Nations SP, Swenson AJ, Factor-Litvak P, Amyotrophic lateral sclerosis & frontotemporal degeneration 2020 Apr 1-10
- Primary lateral sclerosis: consensus diagnostic criteria.
  Turner MR, Barohn RJ, Corcia P, Fink JK, Harms MB, Kiernan MC, Ravits J, Silani V, Simmons Z, Statland J, van den Berg LH, Mitsumoto H, Journal of neurology, neurosurgery, and psychiatry 2020 Apr 91 4 373-377
- 'Minimal symptom expression' in patients with acetylcholine receptor antibody-positive refractory generalized myasthenia gravis treated with eculizumab.
  Vissing J, Jacob S, Fujita KP, O'Brien F, Howard JF, Journal of neurology 2020 Mar
- Primary lateral sclerosis (PLS) functional rating scale: PLS-specific clinimetric scale.
  Mitsumoto H, Chiuzan C, Gilmore M, Zhang Y, Simmons Z, Paganoni S, Kisanuki YY, Zinman L, Jawdat O, Sorenson E, Floeter MK, Pioro EP, Fernandes Filho JAM, Heitzman D, Fournier CN, Oskarsson B, Heiman-Patterson T, Maragakis N, Joyce N, Hayat G, Nations S, Scelsa S, Walk D, Elman L, Hupf J, McHale B, Muscle & nerve 2020 02 61 2 163-172
- Safety and efficacy of intravenous bimagrumab in inclusion body myositis (RESILIENT): a randomised, double-blind, placebo-controlled phase 2b trial.
  Hanna MG, Badrising UA, Benveniste O, Lloyd TE, Needham M, Chinoy H, Aoki M, Machado PM, Liang C, Reardon KA, de Visser M, Ascherman DP, Barohn RJ, Dimachkie MM, Miller JAL, Kissel JT, Oskarsson B, Joyce NC, Van den Bergh P, Baets J, De Bleecker JL, Karam C, David WS, Mirabella M, Nations SP, Jung HH, Pegoraro E, Maggi L, Rodolico C, Filosto M, Shaibani AI, Sivakumar K, Goyal NA, Mori-Yoshimura M, Yamashita S, Suzuki N, Katsuno M, Murata K, Nodera H, Nishino I, Romano CD, Williams VSL, Vissing J, Auberson LZ, Wu M, de Vera A, Papanicolaou DA, Amato AA, The Lancet. Neurology 2019 Sep 18 9 834-844
- Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.
  Wolfe GI, Kaminski HJ, Aban IB, Minisman G, Kuo HC, Marx A, Ströbel P, Mazia C, Oger J, Cea JG, Heckmann JM, Evoli A, Nix W, Ciafaloni E, Antonini G, Witoonpanich R, King JO, Beydoun SR, Chalk CH, Barboi AC, Amato AA, Shaibani AI, Katirji B, Lecky BRF, Buckley C, Vincent A, Dias-Tosta E, Yoshikawa H, Waddington-Cruz M, Pulley MT, Rivner MH, Kostera-Pruszczyk A, Pascuzzi RM, Jackson CE, Verschuuren JJGM, Massey JM, Kissel JT, Werneck LC, Benatar M, Barohn RJ, Tandan R, Mozaffar T, Silvestri NJ, Conwit R, Sonett JR, Jaretzki A, Newsom-Davis J, Cutter GR, The Lancet. Neurology 2019 03 18 3 259-268
- Eculizumab improves fatigue in refractory generalized myasthenia gravis.
  Andersen H, Mantegazza R, Wang JJ, O'Brien F, Patra K, Howard JF, Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2019 Mar
- Excellent response to therapeutic plasma exchange in myasthenia gravis patients irrespective of antibody status.
  Usmani A, Kwan L, Wahib-Khalil D, Trivedi J, Nations S, Sarode R Journal of clinical apheresis 2019 Feb
- Long-term safety and efficacy of eculizumab in generalized myasthenia gravis.
  Muppidi S, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Nowak RJ, Andersen H, Casasnovas C, De Bleecker JL, Vu TH, Mantegazza R, O'Brien FL, Wang JJ, Fujita KP, Howard JF Muscle & nerve 2019 Feb
- Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial.
  Statland JM, Moore D, Wang Y, Walsh M, Mozaffar T, Elman L, Nations SP, Mitsumoto H, Fernandes JA, Saperstein D, Hayat G, Herbelin L, Karam C, Katz J, Wilkins HM, Agbas A, Swerdlow RH, Santella RM, Dimachkie MM, Barohn RJ Muscle & nerve 2019 Feb 59 2 201-207
- Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort.
  Murphy J, Factor-Litvak P, Goetz R, Lomen-Hoerth C, Nagy PL, Hupf J, Singleton J, Woolley S, Andrews H, Heitzman D, Bedlack RS, Katz JS, Barohn RJ, Sorenson EJ, Oskarsson B, Fernandes Filho JA, Kasarskis EJ, Mozaffar T, Rollins YD, Nations SP, Swenson AJ, Koczon-Jaremko BA, Mitsumoto H Neurology 2016 Jan
- Phenotypic and molecular analyses of primary lateral sclerosis
  Mitsumoto H, Nagy PL, Gennings C, Murphy J, Andrews H, Goetz R, Floeter MK, Hupf J, Singleton J, Barohn RJ, Nations S, Shoesmith C, Kasarskis E, Factor-Litvak P Neurology: Genetics 2015 1 e3
- ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): Study methodology, recruitment, and baseline demographic and disease characteristics.
  Mitsumoto H, Factor-Litvak P, Andrews H, Goetz RR, Andrews L, Rabkin JG, McElhiney M, Nieves J, Santella RM, Murphy J, Hupf J, Singleton J, Merle D, Kilty M, Heitzman D, Bedlack RS, Miller RG, Katz JS, Forshew D, Barohn RJ, Sorenson EJ, Oskarsson B, Fernandes Filho JA, Kasarskis EJ, Lomen-Hoerth C, Mozaffar T, Rollins YD, Nations SP, Swenson AJ, Shefner JM, Andrews JA, Koczon-Jaremko BA Amyotrophic lateral sclerosis & frontotemporal degeneration 2014 Feb
- Leprosy of Lucio and Latapi with extremity livedoid vascular changes.
  Kourosh AS, Cohen JB, Scollard DM, Nations SP International journal of dermatology 2013 Oct 52 10 1245-7
- A randomized, pilot trial of etanercept in dermatomyositis
  Muscle Study Group Annals of Neurology 2011 70 427-436
- Denture cream: an unusual soure of ecess zinc, leading to hypocupremia and neurologic disease
  Nations SP, Boyer PJ, Love LA et al. Neurology 2008 71 639-643
- Adult Polyglucosan Body Disease Presenting with Levodopa-Responsive Tremor
  Trivedi JR, Wolfe GI, Nations SP, Burns DK, Bryan WW, Dewey RB Arch Neurol Spring 2003 60 764-766
- Peripheral Neuropathy Due to Leprosy.
  Nations SP, Barohn RJ Current treatment options in neurology 2002 May 4 3 189-196
- Randomized, Controlled Trial of Intravenous Immunoglobulin in Myasthenia Gravis
  Wolfe GI, Barohn RJ, Foster BM, Jackson CE, Kissel JT, Day JW, Thornton CA, Nations SP, Bryan WW, Amato AA, Freimer ML, Parry GJ, Mendell JR for the Myasthenia Gravis-IVIG Study Group Muscle & Nerve 2002 26 549-552
- Axonal Multifocal Motor Neuropathy Without Conduction Block or Other Features of Demyelination
  Katz JS, Barohn RJ, Kojan S, Wolfe GI, Nations SP, Saperstein DS, Amato AA Neurology 2002 58 615-620
- A Guide to Autoantibody Testing in Peripheral Neuropathies
  Wolfe GI, Nations SP The Neurologist 2001 7 195-207
- Cervicobrachial Involvement in Diabetic Radiculoplexus Neuropathy
  Katz J, Saperstein DE, Wolfe G, Nations S, Alkhersam H, Amato A, Barohn R Muscle & Nerve 2001 24 794-798
- Maysthenia gravis activities of daily living profile
  Wolfe BI, Baker, NS, Amato AA, Jackson CE, Nations SP, Saperstein OS, Cha CH, Katz JS, Bryan WW, Barohn RJ. Chronic cryptogenic sensory polyneuropathy: clinical and electrophysiologic characteristics Archives of Neurology 1999 56 540-547
- Diatl myasthenia gravis
  Nations SP, Wolfe GI, Amato AA, Jackson CE, Bryan WW, Barohn RJ Neurology 1999 52 632-634
- Leprous Neuropathy: An American Perspective
  Nations SP, Katz JS, Lyde C, Barohn RJ Seminars in Neurology 1998 18 113-124

Research

ALS
Myasthenia Gravis
Myopathies
CIDP

Clinical Focus

Neuromuscular Disorders
Neurophysiology (EMG)