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UT Southwestern Medical Center’s dedicated gastrointestinal cancer team creates individualized treatment plans for patients with stomach/EG junction cancer and uses the latest therapies to treat this complex disease.

As the only National Cancer Institute-designated comprehensive cancer center in North Texas, we deliver the best cancer care available today and push to discover new treatments. NCI designation means we offer patients the ability to participate in the broadest possible range of clinical trials, with access to potential therapies not available at other facilities.

A Specialized Approach to Care

Stomach cancer, also known as gastric cancer, is a type of gastrointestinal cancer that starts in any part of the stomach. Cancer located at the junction of the esophagus and stomach is called esophagogastric (EG) junction cancer or gastroesophageal (GE) junction cancer.

At UT Southwestern Harold C. Simmons Comprehensive Cancer Center, our multidisciplinary team of physicians has extensive experience with stomach/EG junction cancer. Patients benefit from our specialization, our individualized treatment plans, and our access to the most innovative, promising new therapies, such as minimally invasive surgical techniques.

Symptoms and Diagnosis

Symptoms of stomach/EG junction cancer can include:

  • Fatigue
  • Bloated feeling after eating
  • Feeling of fullness after eating small amounts of food
  • Severe, persistent heartburn
  • Severe indigestion that is always present
  • Unexplained, persistent nausea
  • Stomach pain
  • Persistent vomiting
  • Unintentional weight loss

To diagnose the cancer, we perform a physical exam and ask patients about their health, lifestyle (such as smoking and drinking habits), and family medical history. Early tests to diagnose stomach cancer might include X-rays and stool testing for traces of blood.

In addition, we might use one or more of the following tests to diagnose stomach cancer and determine if it has spread:

Treatments for Stomach Cancer

The main treatments for stomach cancer are:

  • Surgery
  • Chemotherapy
  • Targeted therapy
  • Radiation therapy

If a patient’s cancer requires all of these treatments, the standard approach is often to give chemotherapy or radiation before surgery. For patients with very early-stage cancers, surgery alone can be a sufficient treatment to control the tumor.

UT Southwestern’s surgeons are experienced in all the surgical options for treating stomach/EG junction cancer, such as minimally invasive gastrectomy and removal of the necessary lymph nodes.

Support Services

To treat the whole patient, not just the cancer, we offer other resources patients might need during their cancer journey, such as nutrition counseling, support groups, physical therapy and rehabilitation, lifestyle education, genetic counseling, and much more.

Clinical Trials

UT Southwestern offers clinical trials that can provide patients with an opportunity to complement traditional therapy for stomach/EG junction cancer with the newest, most promising treatment strategies. Patients should speak with their doctors about these opportunities.

Related Conditions and Treatments

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Find a Clinical Trial

We have a wide range of clinical trials open to patients with all stages of cancer. Search for opportunities to participate in a cancer study.


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