Muhammad Beg, M.D.

  • Dedman Family Scholar in Clinical Care
  • Internal Medicine - Hematology/Oncology
  • Medical Treatment of Pancreatic Cancer
  • Pancreatic Cancer


Muhammad Shaalan Beg, M.D., has a lot of irons in the fire at UT Southwestern Medical Center. And his patients are the driving force behind everything he does here.

He is Director for Gastrointestinal (GI) Medical Oncology at UT Southwestern. As a medical oncologist, Dr. Beg treats patients with cancer of the pancreas, bile duct, and liver. He is an Associate Professor of Hematology and Medical Oncology and is Medical Director of the Clinical Research Office. Dr. Beg conducts trials for new cancer treatments and is Principal Investigator for the Simmons Comprehensive Cancer Center Experimental Therapeutics Clinical Trials Network (ETCTN) Clinical Trial Network National Cancer Institute (NCI) UM1 grant.

He completed the Leadership Development Program of the American Society of Clinical Oncology where he serves on the Cancer Communications Committee and is on the Editorial Board of ASCO Daily News. He leads the Pancreatic-Hepatobiliary Cancers working group of the ECOG-ACRIN Cancer Research Group’s Gastrointestinal Cancer Core Committee. He is also a member of the National Cancer Institute (NCI) GI Cancer Steering Committee’s Pancreatic Cancer task force. Additionally, he is leading multiple trials on drug combinations in our labs at UT Southwestern.

Prior to joining joined UT Southwestern in 2011, Dr. Beg attended medical school at Aga Khan University in Karachi, Pakistan, where he graduated with honors. He completed his residency in internal medicine and a fellowship in hematology/oncology at the University of Cincinnati.

Dr. Beg is board certified in hematology and medical oncology, and he is a member of the American Association for Cancer Research and the American Society of Clinical Oncology.

His research has been featured in national and international cancer meetings, and he has published articles in many peer-reviewed medical publications including Journal of Clinical Oncology, JAMA Oncology, Clinical Cancer Research and Cancer Cell. Dr. Beg is often invited to give lectures on pancreatic cancer treatments and health information technology, and he is a reviewer for multiple oncology journals.

Dr. Beg has been included in D Magazine's Best Doctors list several times, including 2021, and was named a Texas Monthly Super Doctor from 2013 to 2018.

Personal Note

When he’s not working, Dr. Beg spends quality time with his wife and their two children. He also enjoys traveling and exploring the outdoors. He is very interested in understanding how to use electronic communication tools such as social media to better communicate scientific findings.

Meet Dr. Beg

Medical Oncologist and GI Cancer Specialist

In the fight against gastrointestinal cancers, Muhammad Shaalan Beg, M.D., is leading the charge.

"I spend a lot of time trying to understand what my patients' needs and expectations are, and what they want me to help them achieve. Is it to continue being able to work their current job, keep playing the piano, or attend a grandchild's graduation party? I need to understand where my patient is coming from."

As a medical oncologist at UT Southwestern Medical Center’s Simmons Cancer Center, Dr. Beg treats patients with pancreatic, liver, colorectal, and stomach cancer, as well as rare cancers such as neuroendocrine tumors and gastrointestinal stromal tumors (GIST). He is also Associate Professor of Hematology and Medical Oncology and is co-Leader of the Gastrointestinal Cancer Multidisciplinary team.

Dr. Beg is very active in clinical research including leading clinical trials at the Simmons Cancer Center, where he is bringing promising basic science discoveries from the lab to the clinic to better care for his patients.

He believes that GI cancers are best treated by a group of doctors. GI cancer patients are a very special and diverse group with specific needs, so Dr. Beg spends a lot of time getting to know his patients to assess their needs and expectations for cancer care. He believes in offering the best, personalized care available, which includes cutting-edge medical care, clinical trials, and innovations in surgery.

“We need to provide patients with more opportunities, and the best way to do that is through clinical trials,” Dr. Beg says. “My goal is to bring ideas from the lab and see how we can apply that to the clinic. We always think of clinical trials as something we are investing our time and money in, but if it’s not helping the patient, it’s not really a benefit at all.”

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Education & Training
  • Fellowship - University of Cincinnati (2008-2011), Hematology Oncology
  • Residency - University of Cincinnati College of Medicine (2005-2008), Internal Medicine
  • Medical School - Aga Khan Univ, Pakistan (1998-2003)
Professional Associations & Affiliations
  • American Society of Clinical Oncology (2008)
  • American Association for Cancer Research (2011)
Honors & Awards
  • Resident Teacher Award 2008, University of Cincinnati
  • Leadership Development Program - American Society of Clinical Oncology 2018-2019
  • Leadership Emerging in Academic Departments (LEAD) Program - UT Southwestern Medical Center 2016
  • Cancer Communications Committee - American Society of Clinical Oncology 2018-2021
  • Pancreatic Cancer Task Force, GI Cancer Steering Committee, NCI 2017-2021
  • Chair, Pancreatic-Hepatobiliary Working Group, GI Core Committee ECOG/ACRIN 2017-2021
  • D Magazine Best Doctor 2021
Books & Publications
  • Cancer of Pancreas, Liver, and Bile Duct
  • Digital Health
  • Experimental Therapeutics
  • Clinical Informatics
  • Early Phase Drug Development, Phase I/II Clinical Trials
  • Cancers of the Gastrointestinal Tract
  • Decentralized Clinical Trials

Clinical Focus

  • Medical Treatment of Pancreatic Cancer
  • Pancreatic Cancer
  • Liver Cancer
  • Gallbladder/Bile Duct (Cholangiocarcinoma) Cancer

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Q&A by Dr. Beg