Shelby Holt, M.D.

Shelby Holt, M.D.

  • Surgery - GI/Endocrine Surgery
  • Endocrine Surgery Treatments
  • Parathyroid & Thyroid Conditions


Shelby Holt, M.D., is a Professor in UT Southwestern Medical Center’s Department of Surgery, where she specializes in thyroid surgery and parathyroid surgery. Dr. Holt serves as the Chief of Endocrine Surgery at UT Southwestern.

Dr. Holt was valedictorian of her high school graduating class in San Angelo, Texas. She completed her undergraduate degree in biology at Southwestern University, and earned her medical degree at the University of Texas Health Science Center in Houston, where she finished first in her class. She completed general surgery residency training at UT Southwestern Medical Center, during which time she was selected to serve as Administrative Chief Resident and was a member of the resident evaluation committee. Prior to joining the UT Southwestern faculty, she completed advanced training in endocrine surgery through a fellowship at the Mayo Clinic and the University of Michigan. 

As a faculty member, Dr. Holt has made national and international presentations for surgical organizations. She organized the First Annual Texas Endocrine Surgery symposium, a collaborative effort between the three University of Texas medical school campuses. She serves as a Co-Director of the Bimonthly Thyroid Cancer Conference at UT Southwestern and is a reviewer for Surgery, the World Journal of Surgery and the Annals of Surgical Oncology.

Dr. Holt is a Fellow of the American College of Surgeons, as well as a member of multiple professional organizations including the American College of Surgeons, the American Association of Endocrine Surgeons, the American Association of Clinical Endocrinologists, the International Association of Endocrine Surgeons, the Western Surgical Association, the Texas Surgical Society, and the Parkland Surgical Society.

In 2018, she was named a Super Doctor by Texas Monthly. In 2010, D Magazine recognized Dr. Holt with a Best Doctor award. She has received numerous accolades for her teaching, including a Special Recognition for Outstanding Achievement in Resident Teaching award in 2012 and a Core Clerkship Teaching Award for Surgery in 2008. 

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Meet Dr. Holt

Endocrine surgeon Shelby Holt, M.D., performs nearly 400 thyroid and parathyroid surgeries each year, making her one of the most experienced in North Texas. Dr. Holt treats a wide range of thyroid and parathyroid diseases, including hyperparathyroidism, thyroid cancer, thyroid masses and tumors, and thyroid nodules.

With thyroid and parathyroid surgery, the experience of the surgeon has a direct impact on patients’ outcomes. Dr. Holt’s expertise is validated by the large number of referrals she receives from other physicians, including highly complicated cases that other doctors can’t or won’t treat. 

D Magazine Best Doctor, Dr. Holt prides herself on offering excellent patient care in addition to technical expertise. It’s one of the reasons she chose to focus on thyroid and parathyroid surgery.

“It is very rewarding to make a significant impact on my patients’ lives with very well-tolerated endocrine surgical procedures, “she says.

Dr. Holt was at the forefront of establishing UT Southwestern Medical Center’s multidisciplinary thyroid cancer conference to discuss research and treatment options to achieve patient-focused solutions. She also runs a multidisciplinary tumor clinic where she monitors and treats endocrine cancer patients.

“We have dedicated radiologists and pathologists who are experts at imaging and diagnosing thyroid and parathyroid diseases and cancer – a critical first stop in the treatment process. We all work together as a team to provide the best patient care,” Dr. Holt says.

As a surgical resident at UT Southwestern, Dr. Holt was encouraged to specialize in endocrine surgery. After fellowship training at the Mayo Clinic and the University of Michigan, she joined UT Southwestern’s faculty and is now the Chief of Endocrine Surgery.

Dr. Holt credits her team’s multidisciplinary approach to care as key to the success they’ve achieved at UT Southwestern.

In her research, Dr. Holt constantly seeks better ways to treat patients. She studies parathyroid surgery outcomes and long-term monitoring of thyroid cancer patients.

Dr. Holt is also active in training residents and works closely with physicians in the community. As part of those efforts, she organized the First Annual Texas Endocrine Surgery symposium, in which doctors come together to present research and learn about the latest treatments and discoveries related to endocrinology.

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Education & Training
  • Fellowship - University of Michigan (2000-2001), Endocrine Surgery
  • Residency - Parkland Health and Hospital System (1996-2000), General Surgery
  • Internship - Parkland Health and Hospital System (1995-1996), General Surgery
  • Medical School - University of Texas Health Science Center, Houston (1991-1995)
Professional Associations & Affiliations
  • Western Surgical Society
  • Texas Surgical Society
  • American College of Surgeons
  • American Association of Endocrine Surgeons
  • American Association of Clinical Endocrinologists
Honors & Awards
  • Valedictorian of Graduating Class 1987, San Angelo Central High School
  • Alpha Omega Alpha Honor Society 1994, University of Texas Medical School, Houston
  • Faculty Teaching Award 2004, University of Texas Southwestern Medical Center - Dept. of Surgery
Books & Publications
  • Evaluation and management of endocrine disease

Clinical Focus

  • Endocrine Surgery Treatments
  • Parathyroid & Thyroid Conditions

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Q&A by Dr. Holt

Showing 2 locations

Endocrine Surgery

at UT Southwestern Monty and Tex Moncrief Medical Center at Fort Worth 600 South Main Street, 2nd Floor, Suite 2.200
Fort Worth, Texas 76104
817-882-2420 Directions

Multidisciplinary Surgery Clinic

at Outpatient Building 1801 Inwood Road, 7th Floor, Suite 100
Dallas, Texas 75390
214-645-2900 Directions Parking Info