Biography

Georgios Karagkounis, M.D., is an Assistant Professor in the Department of Surgery at UT Southwestern Medical Center.

He specializes in colon and rectal cancer, with a focus on adults under age 50; liver malignancies; and peritoneal surfaces malignancies. He has advanced training in minimally invasive techniques, including robotic surgery; cytoreductive surgery; and regional therapies, including hepatic artery infusion pump chemotherapy and hyperthermic intraperitoneal chemotherapy (HIPEC).

Dr. Karagkounis earned his medical degree with honors at the University of Athens School of Medicine in Greece and gained advanced training in surgical oncology through a research fellowship at Johns Hopkins University. He completed his general surgery residency and a cancer biology research fellowship at the Cleveland Clinic and, following that, a clinical fellowship in complex general surgical oncology at the Memorial Sloan Kettering Cancer Center.

Certified by the American Board of Surgery, he joined the UT Southwestern faculty in 2021.

Dr. Karagkounis is a member of several professional organizations, including the American College of Surgeons (ACS), the American Society of Colon and Rectal Surgeons (ASCRS), the Americas Hepato-Pancreato-Biliary Association (AHPBA), the Association for Academic Surgery (AAS), the Society of Surgical Oncology (SSO), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES).

His research in gastrointestinal oncology has been presented at national and international meetings and published in several journals.

Education & Training
  • Medical School - University of Athens School of Health Sciences, Greece (2004-2010)
  • Research Fellowship - Johns Hopkins University (2011-2012), Surgical Oncology
  • Residency - Cleveland Clinic Foundation (2012-2019), General Surgery
  • Research Fellowship - Cleveland Clinic Foundation (2014-2016), Cancer Biology
  • Chief Resident - Cleveland Clinic Foundation (2018-2019), General Surgery
  • Fellowship - Memorial Sloan-Kettering Cancer Center (2019-2021), Surgical Oncology
Professional Associations & Affiliations
  • American College of Surgeons (ACS)
  • American Society of Colon and Rectal Surgeons (ASCRS)
  • Americas Hepato-Pancreato-Biliary Association (AHPBA)
  • Association for Academic Surgery (AAS)
  • Society of Surgical Oncology (SSO)
  • Society for Surgery of the Alimentary Tract (SSAT)
  • Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)
Honors & Awards
  • Steiger Award for Significant Research Contribution 2019, Cleveland Clinic Foundation
  • Research Forum Works in Progress Award 2017, American Society of Colon and Rectal Surgeons Annual Meeting
  • Best Paper 2016, American Society of Colon and Rectal Surgeons Annual Meeting
  • First Place, Annual Resident Essay Competition 2016, Cleveland Surgical Society
  • Career Development Award 2015, Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)
Books & Publications
Research
  • Understanding the reasons behind the increase in early-onset colon and rectal cancer (i.e., in patients under 50), determining the differences between early-onset and average-onset tumors, and identifying potential treatments specific to early-onset patients
  • Understanding the mechanisms behind the peritoneal spread (carcinomatosis) of gastrointestinal cancers to discover new therapy options

Clinical Focus

  • Colorectal Cancer
  • Liver malignancies
  • Peritoneal surfaces malignancies

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