Turning to the journal’s Original Research Articles, Jarett Barry, M.D., discussed his paper addressing coronary artery calcium (CAC) in individuals who exercise below, at, or well above guideline-recommended levels. In summary, CAC in individuals who exercise a tremendous amount is indeed clinically meaningful and not an artifact. Gregory Marcus, M.D., M.A.S., discussed his randomized control trial comparing retrograde access to the LV versus trans-septal access in VT ablation procedures, focusing on brain lesions detected on MRI. Josefine Windfeld-Mathiasen, M.D., presented her exciting work on the use of anabolic steroids in individuals in Denmark, uncovering a clear signal of cardiovascular harm. Jonathan Leor, M.D., discussed his paper reporting that infarcted LV tissue releases extracellular vesicles that unequivocally promote cancer progression. Finally, MaryJane Farr, M.D., M.Sc., discussed her paper dissecting the challenges of survivorship following cardiogenic shock.
In aggregate, this exciting symposium – as in previous years -- afforded a brief summary of some of the most outstanding science in our field published in Circulation.