Comprehensive Heart and Vascular Center

Circulation Symposium at #AHA25

By Joseph A. Hill, M.D., Ph.D.

Professor of Internal Medicine and Molecular Biology
Director of the Harry S. Moss Heart Center

Dr. Joseph A. Hill

Once again, we were pleased to host our annual Circulation symposium at the AHA Scientific Sessions. This year’s session, the tenth consecutive one orchestrated by our team, was titled “Circulation: Innovation in Cardiovascular Science and Medicine” – an informative and fun 75 minutes devoted to canvassing some of the best content published this year in Circulation.

Representing our Centennial Collection initiative of weekly short summaries of cardiovascular topics commemorating the 100th anniversary of the AHA, Peter Libby, M.D., summarized recent advances in our understanding of the biology of atherosclerosis, emphasizing the importance of pivoting from the arterial lumen to a focus on the atherosclerotic lesion itself. Taufiek Rajab, M.D., discussed the exciting area of partial heart transplantation, in which – as one example – implanted native heart valves can grow with the growth of the recipient heart, a potential breakthrough in cardiac transplantation in children.

“This year’s session, the tenth consecutive one orchestrated by our team, was … an informative and fun 75 minutes devoted to canvassing some of the best content published this year in Circulation.”

Joseph A. Hill, M.D., Ph.D.

Turning to the journal’s Original Research Articles, Jarett Barry, M.D., discussed his paper addressing coronary artery calcium (CAC) in individuals who exercise below, at, or well above guideline-recommended levels. In summary, CAC in individuals who exercise a tremendous amount is indeed clinically meaningful and not an artifact. Gregory Marcus, M.D., M.A.S., discussed his randomized control trial comparing retrograde access to the LV versus trans-septal access in VT ablation procedures, focusing on brain lesions detected on MRI. Josefine Windfeld-Mathiasen, M.D., presented her exciting work on the use of anabolic steroids in individuals in Denmark, uncovering a clear signal of cardiovascular harm. Jonathan Leor, M.D., discussed his paper reporting that infarcted LV tissue releases extracellular vesicles that unequivocally promote cancer progression. Finally, MaryJane Farr, M.D., M.Sc., discussed her paper dissecting the challenges of survivorship following cardiogenic shock.

In aggregate, this exciting symposium – as in previous years -- afforded a brief summary of some of the most outstanding science in our field published in Circulation.

UT Southwestern Medical Center graphic with text "Solving Complex Heart Cases"

Physician Update: AHA Special Edition

Read more articles from our most relevant research presented at the 2025 AHA Scientific Sessions.

Learn more here